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Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

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NCT ID: NCT03169933 Completed - Prostate Cancer Clinical Trials

Combined, Intensified and Modulated Adjuvant Therapy in Prostate Carcinoma

Start date: January 2, 2004
Phase: Phase 2
Study type: Interventional

Patients with high risk prostate cancer may benefit from radiotherapy after radical prostatectomy. The investigators postulated that adjuvant androgen deprivation therapy (ADT), radiation dose escalation, and selective pelvic irradiation may improve outcome. A phase II trial was designed to prove that combined-intensified-modulated-adjuvant (CIMA) treatment may improve 5-year biochemical relapse free survival (bRFS) from 75% to 90% in high risk patients. The delivered dose to tumor bed and pelvic nodes was 64.8-70.2 Gy and 45 Gy (57% of patients), respectively, and 69% received ADT.

NCT ID: NCT03162523 Completed - Prostate Cancer Clinical Trials

Experiences With HDR-brachytherapy in Norway

Start date: January 2004
Phase: N/A
Study type: Observational [Patient Registry]

There are 3 articles that will be written about the experience with HDR-brachytherapy (HDR-BT) in patients with high-risk prostate cancer in Norway as part of a doctorial thesis-project. The project will focus on survival, side-effects and dosimetry variables as the main points of interest.

NCT ID: NCT03105869 Completed - Prostate Cancer Clinical Trials

Repeatability of Positron Emission Tomography (TEP) With fluorométhyl-(18F)-diméthyl-2-hydroxyéthyl-ammonium

Start date: December 16, 2014
Phase: N/A
Study type: Interventional

Monocentric study. Objective : Determination of the repeatability of fluorocholine PET/CT in prostate cancer

NCT ID: NCT03084913 Completed - Prostate Cancer Clinical Trials

Olive Oil v Prostate Cancer Foundation Diet for Treatment of Prostate Cancer

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

This study compared a plant-based, olive oil diet to the diet recommended by the Prostate Cancer Foundation for weight loss and improvement in some laboratory biomarkers.

NCT ID: NCT03077126 Completed - Prostate Cancer Clinical Trials

Feasibility Study of Ultrasound Elastography Detecting Prostate Cancer

Start date: April 11, 2013
Phase: N/A
Study type: Interventional

The main purpose of this study is to determine the accuracy and feasibility (possibility) of Aixplorer® ShearWave Elastography (SWE™) Ultrasound System (made by SuperSonic Imagine, Inc.) for detecting prostate cancer in men undergoing radical prostatectomy.

NCT ID: NCT02974231 Completed - Prostate Cancer Clinical Trials

Intensity-modulated Radiation Therapy From 70Gy to 80Gy in Localized Prostate Cancer

Start date: December 2014
Phase: N/A
Study type: Observational

The objective is to report outcomes,including grade ≥2 overall late rectal and urinary toxicity and biochemical control rates in patients treated with IMRT (70 gy, 74 Gy and 80 Gy)

NCT ID: NCT02954289 Completed - Prostate Cancer Clinical Trials

Cooking Class Intervention Project for Men With Prostate Cancer and Their Partners

Start date: February 2014
Phase: N/A
Study type: Interventional

Prostate cancer is one of the most commonly diagnosed cancers in Canada, with 24,000 new cases estimated for 2015. Prostate cancer patients often live with uncomfortable side effects of treatment, such as a decrease in bone health, weight gain, and challenges to their interpersonal relationships. Nutrition can improve outcomes for PCa survivors; however, dietary interventions for prostate cancer patients are limited. Therefore, this is a feasibility study that tests the impact of an innovative intervention to promote healthy nutrition and weight control for prostate cancer survivors and their partners. The objectives are to assess the feasibility of the intervention, specifically: - Accrual, retention and adherence, and participant satisfaction - Candidate measures for primary outcomes in future studies The intent is to evaluate how well the classes work and identify ways to make them more successful. At the end of the study, the investigators will know if this approach shows merit to be tested further through a randomized controlled trial.

NCT ID: NCT02928432 Completed - Prostate Cancer Clinical Trials

SWITCH: Study of the Prednisone to Dexamethasone Change in mCRPC Patients Treated With Abiraterone

Start date: June 2013
Phase: Phase 2
Study type: Interventional

Abiraterone acetate (AA) has shown a favourable impact in overall survival, administered with prednisone to decrease the adverse event related to CYP171A suppression. Our hypothesis is that the change of prednisone to dexamethasone in CRPC patients that progress biochemically to AA + prednisone can improve the number and the length of the responses, and also improve tolerance to treatment, decreasing the adverse events associated to a moderate dosage of steroids used chronically.

NCT ID: NCT02882178 Completed - Prostate Cancer Clinical Trials

Formal Consensus Method to Evaluate the Conformity of Prescription of a Recently Approved Chemotherapy Treatment in an Observatory Study

Start date: November 2013
Phase: N/A
Study type: Observational

Cabazitaxel is a second line chemotherapy drug recently approved for the treatment of metastatic castration-resistant prostate cancer. To investigate whether the precautions for the use of cabazitaxel (contraindications, hepatic function, premedication for hypersensitivity, prophylactic treatments, dose and dose adjustment, as well as conditions of administration) are respected in routine practice, an observational cohort study will be implemented in 32 oncology centres of South-West region of France (CABOBS study). The primary objective of this cohort is to evaluate the conformity of cabazitaxel prescriptions with the Summary of Product haracteristics (SPC) in clinical practice (indications and monitoring methods) and according to the conditions of use. Panel of experts were convened to assess the conformity of prescription of cabazitaxel with a Delphi consensus method. The Delphi method is most suited to areas where a limited number of evidences are available to enable a recommendation or guidelines to be drawn. Moreover, all the evaluated items came from an official document provided by the EMA, the SPC of cabazitaxel. Thus, it is expected from the experts to select the most relevant items. In the frame of the CABOBS study, this method will allow to select items of the SPC list according to their importance, and to define the primary objective of conformity to cabazitaxel conditions of use.

NCT ID: NCT02858128 Completed - Prostate Cancer Clinical Trials

WB-DW-MRI vs CHOLINE-PET/CT for Selecting Treatments in Recurrent Prostate Cancer

Start date: October 2014
Phase: N/A
Study type: Observational

The purpose of this study is to determine the effectiveness of whole-body diffusion-weighted magnetic resonance imaging (WB-DW- MRI) in detecting metastases by comparing the results with those from choline-positron emission tomography-computed tomography (choline-PET/CT) in patients with metastatic/oligometastatic prostate cancer. Patients with this disease profile who could benefit from treatment with stereotactic body radiation therapy (SBRT) were selected and their responses to these techniques were rated.