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Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

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NCT ID: NCT03297385 Completed - Prostate Cancer Clinical Trials

Dynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen Ablation

DARANA
Start date: August 28, 2014
Phase: Phase 2
Study type: Interventional

Rationale: Understanding the mechanisms of enzalutamide as an androgen receptor inhibitor in early prostate cancer could lead to improved patient selection for treatment. Objective: To study the effects of enzalutamide on surgical margin status and AR / DNA interaction and gene expression. Intervention : Men with localized prostate cancer will undergo an additional set of targeted tumor biopsies and will be subsequently treated with 3 months of enzalutamide. The prostatectomy specimen will be additionally sampled, ex vivo.

NCT ID: NCT03233672 Completed - Prostate Cancer Clinical Trials

Hypo-fractionated Postoperative IMRT in Prostate Cancer

Start date: September 18, 2007
Phase: N/A
Study type: Interventional

To report the outcome of hypo-fractionated radiotherapy after radical prostatectomy (RP) for prostate cancer (PCa) using IMRT-SIB. 124 patients with PCa at high risk of relapse after RP or diagnosis of biochemical relapse were included. Patients received 62.5 Gy to the prostate bed (PB) and 45 Gy to pelvis nodes in 25 fractions. Androgen suppressive therapy was prescribed based on NCCN risk categories. Median follow-up was 30 months.

NCT ID: NCT03214055 Completed - Prostate Cancer Clinical Trials

Effect of Mannitol on Optic Nerve Sheath Diameter in Patients Undergoing Robotic Prostatectomy

Start date: July 12, 2017
Phase: N/A
Study type: Observational [Patient Registry]

We aim to evaluate the change in optic nerve sheath diameters as a surrogate of intracranial pressure before and after mannitol administration in patients who undergo robot assisted laparoscopic radical prostatectomy with pneumoperitoneum and Trendelenburg position.

NCT ID: NCT03211104 Completed - Prostate Cancer Clinical Trials

Comparison of Duration of Treatment Interruption With or Without Curcumin During the Off Treatment Periods in Patients With Prostate Cancer Undergoing Intermittent Androgen Deprivation Therapy

Start date: August 30, 2007
Phase: N/A
Study type: Interventional

This was a placebo-controlled, double-blind, randomized trial designed with the aim of establishing whether curcumin influenced the duration of treatment interruption and rate of prostatic specific antigen(PSA) progression, compared with placebo among men with prostate cancer receiving intermittent androgen deprivation therapy.

NCT ID: NCT03169933 Completed - Prostate Cancer Clinical Trials

Combined, Intensified and Modulated Adjuvant Therapy in Prostate Carcinoma

Start date: January 2, 2004
Phase: N/A
Study type: Interventional

Patients with high risk prostate cancer may benefit from radiotherapy after radical prostatectomy. The investigators postulated that adjuvant androgen deprivation therapy (ADT), radiation dose escalation, and selective pelvic irradiation may improve outcome. A phase II trial was designed to prove that combined-intensified-modulated-adjuvant (CIMA) treatment may improve 5-year biochemical relapse free survival (bRFS) from 75% to 90% in high risk patients. The delivered dose to tumor bed and pelvic nodes was 64.8-70.2 Gy and 45 Gy (57% of patients), respectively, and 69% received ADT.

NCT ID: NCT03162523 Completed - Prostate Cancer Clinical Trials

Experiences With HDR-brachytherapy in Norway

Start date: January 2004
Phase: N/A
Study type: Observational [Patient Registry]

There are 3 articles that will be written about the experience with HDR-brachytherapy (HDR-BT) in patients with high-risk prostate cancer in Norway as part of a doctorial thesis-project. The project will focus on survival, side-effects and dosimetry variables as the main points of interest.

NCT ID: NCT03105869 Completed - Prostate Cancer Clinical Trials

Repeatability of Positron Emission Tomography (TEP) With fluorométhyl-(18F)-diméthyl-2-hydroxyéthyl-ammonium

Start date: December 16, 2014
Phase: N/A
Study type: Interventional

Monocentric study. Objective : Determination of the repeatability of fluorocholine PET/CT in prostate cancer

NCT ID: NCT03084913 Completed - Prostate Cancer Clinical Trials

Olive Oil v Prostate Cancer Foundation Diet for Treatment of Prostate Cancer

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

This study compared a plant-based, olive oil diet to the diet recommended by the Prostate Cancer Foundation for weight loss and improvement in some laboratory biomarkers.

NCT ID: NCT03077126 Completed - Prostate Cancer Clinical Trials

Feasibility Study of Ultrasound Elastography Detecting Prostate Cancer

Start date: April 11, 2013
Phase: N/A
Study type: Interventional

The main purpose of this study is to determine the accuracy and feasibility (possibility) of Aixplorer® ShearWave Elastography (SWE™) Ultrasound System (made by SuperSonic Imagine, Inc.) for detecting prostate cancer in men undergoing radical prostatectomy.

NCT ID: NCT02974231 Completed - Prostate Cancer Clinical Trials

Intensity-modulated Radiation Therapy From 70Gy to 80Gy in Localized Prostate Cancer

Start date: December 2014
Phase: N/A
Study type: Observational

The objective is to report outcomes,including grade ≥2 overall late rectal and urinary toxicity and biochemical control rates in patients treated with IMRT (70 gy, 74 Gy and 80 Gy)