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Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

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NCT ID: NCT03735680 Not yet recruiting - Breast Cancer Clinical Trials

A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer

Start date: February 28, 2019
Phase: Phase 2
Study type: Interventional

This study is to evaluate diagnostic performance, safety and timing of post-dose imaging of ONM-100, an intraoperative fluorescence imaging agent for the detection of cancer in patients with solid tumors undergoing routine surgery.

NCT ID: NCT03734653 Not yet recruiting - Prostate Cancer Clinical Trials

Testosterone Therapy in Castration Resistant Prostate Cancer

Start date: December 2018
Phase: Early Phase 1
Study type: Interventional

This is an open-labeled, single-arm, interventional pilot study. It is being done to determine the feasibility of the administration of transdermal testosterone alternating with enzalutamide, as well as the safety and efficacy.

NCT ID: NCT03734575 Not yet recruiting - Prostate Cancer Clinical Trials

ClariCore System Used in Transperineal Prostate Biopsy

Start date: November 2018
Phase:
Study type: Observational

The overall objective of this study is to acquire ultrasound images, spectral data and prostate tissue biopsy cores using the ClariCore System via a transperineal approach.

NCT ID: NCT03726320 Not yet recruiting - Prostate Cancer Clinical Trials

Trial of Community Health Worker-led Decision Coaching to Promote Shared Decision Making for Prostate Cancer Screening Among Black Male Patients and Their Providers

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Black men are disproportionately affected by prostate cancer, the most common non-cutaneous malignancy among men in the U.S. This randomized trial will evaluate the efficacy of a Community Health Worker-led decision coaching program to facilitate Shared Decision Making (SDM) and Prostate Specific Antigen (PSA) screening among Black men with regards to decision quality, the decision making process, patient-provider communication and PSA utilization for Black men in the primary care setting.

NCT ID: NCT03716739 Not yet recruiting - Prostate Cancer Clinical Trials

Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency

Start date: January 1, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this phase II trial is to determine the efficacy and safety of testosterone replacement therapy (TRT) in improving the symptoms of androgen deficiency and health-related quality of life in men with prostate cancer who have undergone radical prostatectomy.

NCT ID: NCT03712371 Not yet recruiting - Prostate Cancer Clinical Trials

Study of Chitosan for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

Start date: December 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This study will examine the utility of chitosan for reduction of blood or tissue levels of AGEs in patients with prostate cancer who are clinically stable on androgen-deprivation therapy.

NCT ID: NCT03709485 Not yet recruiting - Prostate Cancer Clinical Trials

Evaluation of Gut Microbiome in Patients With Prostate Cancer

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

The research will focus on the possible connection between prostate cancer, and various species of bacteria in the large intestine. In consecutive patients, referred to prostate biopsies, rectal swabs will be taken before the biopsies and before antibiotic treatment. The gut flora will be examined and characterized by a microbiome analysis tool. Negative patients will serve as internal control. The investigators will look for association between prostate cancer of various grades and the presence of specific enteropathogens in the rectal flora of the participants.

NCT ID: NCT03706365 Not yet recruiting - Prostate Cancer Clinical Trials

A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer

Start date: October 17, 2018
Phase: Phase 2
Study type: Interventional

This study is being done to see how safe and effective abemaciclib is when given together with abiraterone acetate plus prednisone in participants with metastatic castration resistant prostate cancer.

NCT ID: NCT03701581 Not yet recruiting - Prostate Cancer Clinical Trials

4-aminopyridine Treatment for Nerve Injury

Start date: February 1, 2019
Phase: Phase 4
Study type: Interventional

To evaluate the role of 4-aminopyridine (4-AP) on the course of recovery after peripheral nerve traction and/or crush injury. This study aims to test the hypothesis that 4-aminopyridine speeds the often slow and unpredictable recovery after peripheral nerve traction and/or crush injuries.

NCT ID: NCT03700099 Not yet recruiting - Prostate Cancer Clinical Trials

Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Treatment With Docetaxel Followed by Enzalutamide

Start date: December 2018
Phase: Phase 2
Study type: Interventional

This is a prospective biomarker study of patients with metastatic castration-resistant prostate cancer (mCRPC) undergoing sequential treatment with docetaxel and enzalutamide. The participants will undergo serial pre- and post-therapy blood collection for biomarker analysis as part of the primary objective of the study. The primary goal of this study is to evaluate the association of the AR-V7 status and androgen receptor (AR) gene alterations with PSA response to docetaxel and enzalutamide.