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Pain, Postoperative clinical trials

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NCT ID: NCT02477098 Completed - Postoperative Pain Clinical Trials

Preoperative Versus Postoperative Ultrasound-guided Rectus Sheath Block for Sleep Quality and Cytokines of Patients

Start date: October 2015
Phase: Phase 4
Study type: Interventional

Rectus sheath block (RSB) is used for postoperative pain relief in patients undergoing abdominal surgery with a midline incision. It has proved to be effective in preoperative block, but it has not been previously compared with postoperative block. The aim of the present study is to evaluate postoperative pain, sleep quality and changes in the cytokine levels of patients undergoing gynaecological surgery with RSB performed preoperatively versus postoperatively.

NCT ID: NCT02476370 Recruiting - Anxiety Clinical Trials

Effects of Preoperative Relaxation and Intensified Surgery Education in Patients Undergoing Herniotomy

MBM_Hernio
Start date: June 2015
Phase: N/A
Study type: Interventional

This study aims to test the effects of a Preoperative Relaxation intervention and an Intensified Surgery Patient Education on pre- and postoperative wellbeing and health in Patients Undergoing Herniotomy.

NCT ID: NCT02475031 Completed - Postoperative Pain Clinical Trials

Single-shot TAP Block vs Continuous TAP Block

TAP
Start date: July 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether continuous transversus abdominis plane (TAP) block is superior to single shot TAP for postoperative pain after laparoscopic donor nephrectomy

NCT ID: NCT02472314 Completed - Clinical trials for Fracture of Shoulder and Upper Arm

Exparel for Postoperative Pain Management in Shoulder Surgery

Start date: June 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the effect of liposomal Bupivacaine infiltration into the shoulder to continues nerve block with Bupivacaine on postoperative pain control and functional outcomes.

NCT ID: NCT02468934 Completed - Pain Clinical Trials

Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty (TKA) Using the SPRINT System

Start date: October 22, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if electrical stimulation (small levels of electricity) can safely and effectively reduce pain following total knee replacement (or total knee arthroplasty (TKA)). This study involves a device called the SPRINT System. The SPRINT System delivers mild electrical stimulation to nerves in the leg that received the knee replacement. The SPRINT System includes a small wire (called a "lead") that is placed through the skin in the upper leg. It also includes a device worn on the body that delivers stimulation (called the SPRINT Stimulator).

NCT ID: NCT02466542 Completed - Postoperative Pain Clinical Trials

Analgesic Effect of Intraoperative Esmolol in Mastectomies

Esmobreast
Start date: June 2015
Phase: Phase 4
Study type: Interventional

This study aims to compare the quality of perioperative analgesia of esmolol in patients undergoing mastectomy.

NCT ID: NCT02466022 Completed - Clinical trials for Post-operative Pain for Total Knee Arthroplasty

Dexmedetomidine for Sedation in Total Knee Replacements

Start date: June 2015
Phase: Phase 3
Study type: Interventional

Dexmedetomidine has demonstrated benefits both in sedation, and post-operative pain control, with less respiratory depression than other common sedatives. Traditionally, dexmedetomidine has been used with a large loading dose and infusion, which has been known to cause dose-dependent negative side-effects (Abdallah et al., 2013). Single dose dexmedetomidine produces less negative side-effects, but still effective sedation and reduced post-operative pain (Jung et al., 2013). There is evidence for its benefits with general anesthesia but only a few studies exist investigating its benefits when administered for sedation purposes with spinal anesthesia, and no studies primarily examine post-operative opioid consumption. The investigators hypothesize that single dose dexmedetomidine for procedural sedation will reduce opioid consumption after total knee arthroplasty (TKA).

NCT ID: NCT02462174 Completed - Postoperative Pain Clinical Trials

Topical Ketamine Versus Caudal Ketamine for Postoperative Analgesia in Children Undergoing Inguinal Herniotomy

TKversusCK
Start date: May 2015
Phase: Phase 2/Phase 3
Study type: Interventional

To find alternatives to caudal analgesia that could be more safe and effective and to demonstrate the analgesic efficacy of topical ketamine.

NCT ID: NCT02461056 Completed - Breast Cancer Clinical Trials

Synergistic Effect of Ibuprofen and Hydromorphone for Postoperative Pain

Start date: June 2014
Phase: N/A
Study type: Interventional

Intravenous form of ibuprofen is recently approved by FDA and reports are rare on the co-administration with opioids. The investigators searched whether intravenous ibuprofen-hydromorphone combination is synergistic, additive, or infra-additive on postoperative pain using combination index (CI), dose reduction index (DRI) and isobologram.

NCT ID: NCT02460627 Not yet recruiting - Postoperative Pain Clinical Trials

Topical Lidocaine After Arthroscopy on Knee

Start date: May 2015
Phase: Phase 1
Study type: Interventional

More than half of the patients suffer from intensive pain 1-2 days after arthroscopy in the knee. Walking function and physical activities are affected by this intensive pain although local anaesthetic is given in the joint and soft tissue. The patients are often discharged on the same day as the arthroscopy takes place depending on their ability to walk with or without assistive technology. It is a well-known fact that the patient is given a dose of morphine, analgesics or an ice pack on a painful knee to reduce pain intensity. The aim of the project is to study whether pain intensity and analgesics can be additionally reduced by giving local anaesthetic by means of an adhesive tape placed on the skin instead of giving morphine, analgesics or ice pack on a painful knee. The researchers plan to include a cohort of 180 patients: 60 patients having a meniscus sutured, 60 patients having meniscus tissue removed surgically, 60 patients having mucous fold removed surgically. This study is planned to be a pilot study in order to complete a future large medical science study.