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Pain, Postoperative clinical trials

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NCT ID: NCT03440086 Not yet recruiting - Postoperative Pain Clinical Trials

Temporary Application of Abdominal Jackson-Pratt Drain to Reduce Pain After Laparoscopic Surgery in Gynecology

DRAIN-1
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Recent evidence has shown that the onset and intensity of post-operative pain are significantly related to the amount of residual pneumoperitoneum at the end of the surgical procedure. In addition, the use of low pressures of carbon dioxide (CO2) for induction of the pnemoperitoneum has been associated with a reduction in post-operative pain, probably due to a lower abdominal distension and a consequent reduced compression of the pelvic, abdominal and sub-diaphragmatic pain nerve fibers. The reduction of the residual pnemoperitoneum at the end of the surgical procedure could therefore play a key role in the reduction of post-operative pain, with consequent greater comfort for the patient and reduction of the use of analgesics. In view of the available evidence, the aim of the present study is to evaluate whether the application of Jackson-Pratt drain, for one hour from the end of the surgical procedure, can significantly reduce post-operative pain and the need of analgesics in patients undergoing laparoscopic gynecological surgery.

NCT ID: NCT03439787 Not yet recruiting - Pain, Postoperative Clinical Trials

Popliteal Plexus Block for Total Knee Arthroplasty

Start date: March 1, 2018
Phase: Phase 4
Study type: Interventional

This study aims to assess the analgesic effect of the popliteal plexus block as a supplement to a femoral triangle block in patients undergoing total knee arthroplasty

NCT ID: NCT03439566 Recruiting - Pain, Postoperative Clinical Trials

Does Preoperative Pain Levels by Venipuncture Predict Late Postoperative Pain Levels?

Start date: January 15, 2018
Phase: N/A
Study type: Observational

This study wishes to investigate if pain by peripheral venous cannulation (PVC) preoperatively, will predict pain levels after 24 h postoperatively. Furthermore, to investigate moderate/severe pain at the postoperatively at the post-anaesthesia care unit (PACU) is associated with increased late (24h) pain. Additionally, if the PACU nurse is able to predict if the patient will be a high pain responder, by using a clinical judgement. Finally to evaluate the patient's pain-levels at home after discharge and investigate for associations between postoperative pain and post-discharge pain.

NCT ID: NCT03438578 Not yet recruiting - Pain, Postoperative Clinical Trials

Efficacy Safety Score in Postoperative Management

Start date: March 2018
Phase: N/A
Study type: Interventional

The primary aim of this project is to determine whether postoperative patients may benefit from the Efficacy Safety Score (ESS) as a tool for postoperative clinical decision support, with a special focus on the first 24 hours after discharge from the postoperative care unit.

NCT ID: NCT03437707 Completed - Clinical trials for Postoperative Pain Management

Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery

ibuprofen
Start date: January 13, 2018
Phase: N/A
Study type: Interventional

It was aimed to evaluate the effects of IV paracetamol and ibuprofen on postoperative pain, morphine consumption and side effects of morphine in patients underwent lumbar disc surgery associated with moderate to severe postoperative pain.

NCT ID: NCT03437096 Recruiting - Pain Clinical Trials

Postoperative Pain and Venipuncture Pain

venipuncture
Start date: January 15, 2018
Phase: N/A
Study type: Interventional

Association between venipuncture pain and postoperative pain

NCT ID: NCT03435692 Completed - Clinical trials for Post Operative Pain Control

Post Operative Pain Control After Pediatric Hip Surgery

Start date: July 15, 2011
Phase: N/A
Study type: Interventional

Hip surgery in children is painful and the optimal modality for managing post-operative pain has not been established. This prospective randomized controlled trail compares lumbar plexus catheter (LPC), lumbar epidural catheter (LEC) and continuous patient-controlled analgesia with intravenous morphine (PCA).

NCT ID: NCT03434951 Recruiting - Pain, Postoperative Clinical Trials

Intrathecal Morphine and Local Infiltration Analgesia in Total Knee Arthroplasty

Start date: November 6, 2017
Phase: Phase 4
Study type: Interventional

Double-blinded randomized control study investigating intrathecal morphine as an additive to spinal anesthesia in patients undergoing elective total knee arthroplasty. The investigators aim to include a total of 120 patients, randomized to two equal groups. Participants in the intervention group are administered intrathecal 0,2mg morphine and 12,5mg bupivacaine for spinal anaesthesia. Participants in the placebo group are administered 12.5mg bupivacaine and saline to match the volume of intervention goup. Primary end points are opioid consumption and possible adverse effects.

NCT ID: NCT03434847 Recruiting - Pain, Postoperative Clinical Trials

Providing Patients Realistic Expectations of Postoperative Pain

PPREOPP
Start date: October 21, 2017
Phase: N/A
Study type: Interventional

Prospective, randomized, single-blind study, whether perioperative educational improves pain-related postoperative outcomes,

NCT ID: NCT03434275 Not yet recruiting - Pain, Postoperative Clinical Trials

Evaluation of Preoperative N1539 in Total Knee Arthroplasty

Start date: February 2018
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the effect of preoperative administration of N1539 on opioid consumption in subjects undergoing open unilateral total knee arthroplasty compared to placebo.