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Hypertension clinical trials

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NCT ID: NCT03264443 Recruiting - Hypertension Clinical Trials

Hypertension Approaches in the Elderly: a Lifestyle Study

HAEL
Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Two-center randomized, parallel, controlled trial which will compare a pragmatic combined training program with a health education program in 184 older adults with hypertension. This study will last 12 weeks with assessments conducted at baseline, previously to the group allocation, and after interventions. There is a set of secondary outcomes which show clinical importance to the elderly population and are possibly influenced by the tested intervention.

NCT ID: NCT03261245 Recruiting - Clinical trials for Women Who Gave Birth at Dijon and Besançon CHUs Between 2005 and 2009

Relationship Between Multi-exposure to Noise and Air Pollution and the Onset of Hypertension Disorders During Pregnancy

HTA-BQuA
Start date: March 2016
Phase: N/A
Study type: Observational

This retrospective study aimed to analyse the relationship between multi-exposure to noise and air pollution the onset of hypertension disorders during pregnancy It will be conducted in 2650 mothers who gave birth at Dijon or Besançon CHU between 2005 and 2009 split into two groups: - 530 cases (women who experienced hypertension disorders during pregnancy - 2120 controls (women who did not experience a hypertension disorder during pregnancy)

NCT ID: NCT03257488 Recruiting - Clinical trials for Sleep Apnea, Obstructive

Screening of Obstructive Sleep Apnea Syndrome in Patients With Resistant Systemic Arterial Hypertension: Pilot Study

Start date: April 2015
Phase: N/A
Study type: Interventional

This study evaluates the utility and reliability of Somnocheck micro Weinmann for obstructive sleep apnea syndrome (OSAS) screening in patients affected by resistant systemic arterial hypertension. Results are compared with a modified portable sleep apnea testing (type III portable monitoring: Somnocheck 2 Weinmann).

NCT ID: NCT03255746 Recruiting - Hypertension Clinical Trials

HELP-HY: Health Education and sLeep Program in HYpertension

Start date: April 19, 2018
Phase: N/A
Study type: Interventional

Hypertension is the major risk factor for cardiovascular and cerebrovascular diseases worldwide. The escalating prevalence of inadequate sleep now parallels that of hypertension. Observational and experimental evidence favoring a causal relation between insufficient sleep and hypertension are particularly compelling - sleeping 6 hours or less per night is associated with a 20-32% higher probability of incident hypertension. Since sleep curtailment is largely voluntary, sleep deficiency may be corrected and the detrimental health consequences potentially reversed. In this study the investigators aim to investigate the effects of 8 weeks of sleep enhancement/extension vs health education in prehypertensive and stage 1 hypertensive subjects who report habitual short sleep (≤6.5 hours/night).

NCT ID: NCT03254914 Recruiting - Hypertension Clinical Trials

Fimasartan Optimal Reduction Targeting Elevated Blood Pressure: the FORTE Study

Start date: August 9, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this study is to evaluate the effect of home blood pressure monitoring on controlling blood pressure and correlation between home blood pressure and clinic blood pressure in hypertensive patients receiving two or more concomitant antihypertensive agents including fimasartan

NCT ID: NCT03254446 Recruiting - Hypertension Clinical Trials

Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension

Start date: March 12, 2018
Phase: Phase 3
Study type: Interventional

The phase III trial is designed with an aim of determining the efficacy of Investigational Product TRC150094 in concurrently reducing non-traditional risk factors for CV risk i.e., HbA1c, MAP and non-HDL cholesterol. This study will be a randomized, double blind, parallel group, placebo controlled, multi-centre, multinational study in 1250 subjects. All the study subjects will receive once daily dose of TRC150094 45 mg or placebo tablets in addition to their standard of care, for 24 weeks followed by roll over to a safety extension phase of 26 weeks.

NCT ID: NCT03253172 Recruiting - Hypertension Clinical Trials

Potassium Supplementation in CKD

K+ in CKD
Start date: July 1, 2017
Phase: N/A
Study type: Interventional

The current high-sodium, low-potassium diet contributes to the high prevalence of high blood pressure (hypertension). Indeed, the anti-hypertensive effects of potassium supplementation are well-established. Hypertension is even more prevalent and resistant in patients with chronic kidney disease (CKD) and contributes to further decline in kidney function. Four recent epidemiological studies (published 2014 - 2016) showed that higher dietary potassium intake was associated with better renal outcomes. All studies recommended an intervention study with potassium supplementation in patients with CKD, but this has not been performed. The aim of this study is to study the renoprotective effect of potassium supplementation in patients with CKD (stage 3b or 4, i.e. estimated glomerular filtration rate [eGFR] 15 - 45 ml/min/1.73 m2).

NCT ID: NCT03249285 Recruiting - Hypertension Clinical Trials

Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)

PGX-HT
Start date: March 2016
Phase: Phase 3
Study type: Interventional

This is a pharmacogenomic prospective , four-arms, parallel groups, active comparator controlled study in essential hypertensive patients never treated before. Each patient will be genotyped for SNPs (single nucleotide polymorphism) in preliminary genetic profiles and will be treated according to their genetic profile with Peri (Perindopril) 4 mg or HCTZ ( hydrochlorothiazide) 12.5 mg.

NCT ID: NCT03242135 Recruiting - Clinical trials for Predicting Liver Cell Failure & Portal Hypertension in LC

Role of RDW as Anon Invasive Index for Predicting Liver Cell Failure and Portal Hypertension in Cirrhotic Patient

RDW
Start date: September 21, 2016
Phase: N/A
Study type: Observational

role of RDW as anon invasive method for predicting liver cell failure & portal hypertension in cirrhotic patient

NCT ID: NCT03236350 Recruiting - Hypertension Clinical Trials

Remote Ischaemic Conditioning on Blood Pressure Control in Chronic Kidney Disease Patients

ERIC-BP-CKD
Start date: November 28, 2017
Phase: N/A
Study type: Interventional

Chronic kidney disease (CKD) is one of the leading causes of death and disability in Singapore and worldwide. Hypertension is commonly inadequately controlled in patients with CKD and this is associated with CKD progression and cardiovascular complications. Daily episodes of Remote ischaemic conditioning (termed chronic RIC or CRIC) using transient limb ischaemia/reperfusion applied for 1 to 12 months have been shown to lower systemic blood pressure (SBP), prevent stroke and reduce post-myocardial infarction left ventricular (LV) remodelling in experimental and clinical studies. In the ERIC-BP-CKD feasibility and efficacy study, we hypothesise that CRIC administered for 28 days will lower systemic blood pressure and improve blood pressure control in patients with CKD and hypertension.