LSFG-SKIN, Laser Speckle Flowgraphy

Stroke Clinical Trial

Official title:

LSFG-SKIN, Laser Speckle Flowgraphy

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT03660618
• Other study ID #: 201702725
• Status: Terminated
• Phase: N/A
• Start date: May 23, 2017
• Est. completion date: March 2, 2019

Study information

• Verified date: May 2023
• Source: University of Iowa
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.

Description:

Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 1
• Est. completion date: March 2, 2019
• Est. primary completion date: March 2, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

Controls ?Healthy normal control subjects ages 18-90 Cardiology Subjects

• Ages 18-90
• History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease Dermatology Subjects
• Ages 18-90
• History of inflammatory and cancerous lesions Endocrine Subjects
• Ages 18-90
• History of diabetes, thyroid disease Neurology Subjects
• Ages 18-90
• History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis Psychiatry Subjects
• Ages 18-90
• History of bipolar, schizophrenia, anxiety, depression Surgery Subjects
• Ages 18-90
• History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures. Ophthalmology Subjects
• Ages 18-90
• History of ocular disorders caused by hypo perfusion or inflammatory disorders Exclusion Criteria: Controls
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma Cardiology Subjects
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

3. Dermatology Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma Endocrine Subjects
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma Neurology Subjects
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma Psychiatry Subjects
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma Surgery Subjects
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma Ophthalmology Subjects
• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

Related Conditions & MeSH terms

• Autonomic Neuropathy
• Burns
• Chemotherapy Effect
• Headache
• Heart Failure
• Hemorrhage
• Hypertension
• Intracranial Hemorrhages
• Ischemia
• Migraine
• Multiple Sclerosis
• Pain
• Radiation Injuries
• Scleritis
• Stroke
• TIA
• Uveitis
• Vascular Ischemia

Intervention

Device:
• laser speckle flowgraphy
blood flow state of the skin as real time two dimensional image

Locations

Country	Name	City	State
United States	University of Iowa Department of Ophthalmology	Iowa City	Iowa

Sponsors (1)

Lead Sponsor	Collaborator
Randy Kardon

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Imaging Blood Flow	Imaging blood flow in the tissue is of major importance in the clinical environment	One visit