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Pain clinical trials

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NCT ID: NCT06153589 Not yet recruiting - Pain Clinical Trials

Effectiveness of Musicotherapy in Reducing Pain Induced by Leg Ulcer Care

Start date: January 8, 2024
Phase: N/A
Study type: Interventional

Venous leg ulcer is the final stage of chronic venous disease and only develops due to advanced chronic venous insufficiency. The problems caused by venous disease are initially minor and often neglected, but can impact the quality of life of patients. The prevalence of leg ulcers is estimated at 1% of the general population and 3% to 5% of subjects over 65 years old. Its prevalence increases with age in both men and women. Managing chronic ulcers requires a certain number of care procedures, including debridement. The act of treatment by mechanical debridement is little relieved by the analgesics given beforehand, and can be painful, with risks of bleeding. Musicotherapy, particularly the U-shaped method, has shown its effectiveness in the treatment of pain and anxiety in several areas (geriatrics, intensive care, rheumatology, oncology, etc.). The standardized musicotherapy method of the U-shaped sequence was developed and initially evaluated by clinical studies coordinated by the INSERM unit U1061 (Pr. Jacques Touchon; Dr. Stéphane Guétin). Following the publication of numerous controlled, randomized studies presenting results on the effectiveness in the treatment of pain and anxiety, a digital application was developed in order to standardize the method. The Music Care health application is now a Class 1 Medical Device, with CE marking obtained. This "U-shaped sequence" is standardized and has been clinically validated, which makes Music Care a unique tool available for pain relief. No studies have been found in the literature regarding the use of music therapy during debridement care.

NCT ID: NCT06153277 Not yet recruiting - Pain Clinical Trials

Does Edema Affect the Adjustment of TENS Amplitude

Start date: December 15, 2023
Study type: Observational

The goal of this pre-post clinical trial is to compare the amplitude settings of three different frequency TENS modes (Conventional TENS, LF TENS, HF TENS) in patients who had undergone total knee arthroplasty, both with the preoperative state and with the contralateral knee. The main question it aims to answer is: Can the electrical resistance of edematous tissue be affected and change the TENS amplitude setting? Participants will be evaluated before and after surgery. For each TENS modulation the amplitude at which tingling is felt, the current is clearly felt, and is maximum tolerated and/or muscle contraction occurred, will be documented. TENS amplitudes for all three TENS modes will be compared, both with the preoperative state and with the contralateral knee.

NCT ID: NCT06150963 Completed - Pain Clinical Trials

Virtual Reality for the Management of Pain and Anxiety for Outpatient Interventional Radiology Procedures

Start date: June 10, 2021
Phase: N/A
Study type: Interventional

This study explores the use of virtual reality (VR) to reduce pain and anxiety during thyroid biopsies and PICC line insertions under local anesthesia. One group experienced the procedure with VR, while the other group did not. Participants completed questionnaires before and after the surgery to measure pain and anxiety levels. The main goal is to observe if VR can significantly decrease pain and anxiety during these procedures.

NCT ID: NCT06150911 Recruiting - Pain Clinical Trials

Pain, Anxiety, and Impacts on Oral Health-related Quality of Life for Patients With Orthodontic Treatment

Start date: August 1, 2023
Study type: Observational

The goal of this observational study is to learn about pain, anxiety, and impacts on oral health-related quality of life(OHRQoL) for patients before, during and after orthodontic treatment. The recruited participants with good health are from Kaohsiung medical university and local dental clinics . The main questions it aims to answer are: 1. The differences of pain, anxiety, and impacts on oral health-related quality of life(OHRQoL) for patients before, during and after orthodontic treatment. 2. The correlation of pain, anxiety and oral health-related quality of life in our participant 3. The differences of seven domain in OHIP-14 scale in our participants The participants are asked to complete a self-administered in different time point.

NCT ID: NCT06150677 Recruiting - Pain Clinical Trials

Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function

Start date: December 1, 2023
Phase: Phase 3
Study type: Interventional

The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent static apneas training session at high lung volume in healthy subjects; also, as secondary objectives, to analyze the cardiovascular and respiratory response produced during the intervention.

NCT ID: NCT06150586 Not yet recruiting - Pain Clinical Trials

Pain Assessment During Less-Invasive-Surfactant-Administration

Start date: November 2023
Study type: Observational

Primary aims of the study are to evaluate the feasibility of Skin conductance (SC) measurements and its correlation to Neonatal Pain and Distress Scale (N-PASS) - scores during the Less-Invasive-Surfactant-Administration (LISA)-procedure in preterm infants. Secondary aims are to evaluate the effect of LISA on the general stress-level in preterm infants with respiratory distress syndrome. The assessment of pain and stress with SC measurement in addition to the subjective assessment with N-PASS may provide more conclusive data on the sensation of pain or stress during the LISA procedure and therefore the necessity of analgosedation. Therefore, this study might help to identify those infants in need for analgosedation, which would allow an individualized approach in the future.

NCT ID: NCT06149429 Recruiting - Depression Clinical Trials

Virtual Reality at End-of-life

Start date: November 7, 2023
Phase: N/A
Study type: Interventional

The purpose of this research is to determine the effect that repeated, personalized virtual reality experiences have on symptom severity, comparing self-reported symptom severity both pre and post each session, and overtime across sessions. We will also determine if this intervention results in a high rating of presence in VR, and if presence is related to the magnitude of the change in symptoms.

NCT ID: NCT06146569 Enrolling by invitation - Pain Clinical Trials

Effects of Transcutaneous Vagus Nerve Stimulation (taVNS) in Individuals With Primary Dysmenorrhea

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

This study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on pain, functional and emotional symptoms, and physical performance in individuals with primary dysmenorrhea (PD).

NCT ID: NCT06144801 Completed - Pain Clinical Trials

The Effect of Coolsense Method on Pain and Comfort in Hemodialysis Patients

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

This study aimed to investigate the impact of the CoolSense method on arteriovenous fistula cannulation pain and the comfort levels of hemodialysis patients.

NCT ID: NCT06141720 Not yet recruiting - Pain Clinical Trials

Feasibility of a Mindfulness Intervention for Endometriosis Surgery

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Endometriosis is a common cause of pelvic pain in women which has been historically under-studied and under-diagnosed. The goal of this research is to pilot-test the feasibility and acceptability of a manualized, single-session brief mindfulness-based intervention (BMBI) among participants with endometriosis-related chronic pelvic pain (ECPP) who undergo surgical treatment, and gather preliminary data necessary for future studies assessing BMBI's impact on outcomes in surgically-treated ECPP. This pilot study will enroll 10-20 adult participants with ECPP to receive either a BMBI adjunctive to treatment as usual (TAU; n=5-10) or education with TAU (n=5-10) prior to their ECPP surgery. The central hypothesis is the BMBI is feasible to deliver pre-operatively, acceptable to patients, and may help improve acute post-surgical outcomes through more adaptive stress coping and pain processing, enabled by mindfulness training.