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Stroke, Ischemic clinical trials

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NCT ID: NCT04986774 Completed - Ischemic Stroke Clinical Trials

Rescue Intracranial Stenting in Acute Ischemic Stroke

RISIS
Start date: August 1, 2019
Phase: N/A
Study type: Interventional

In acute ischemic stroke caused by intracranial large vessel occlusion, rescue intracranial stenting has been recently a treatment option to achieve recanalization in patients with the failure of mechanical thrombectomy. Nevertheless, there are few studies supporting this beneficial treatment in two cerebral circulations. We aimed to analyse whether the use of rescue intracranial stenting would improve prognosis of patients at 3 months.

NCT ID: NCT04952064 Completed - Stroke, Ischemic Clinical Trials

An Exploratory Study of Ganglioside GM1 in Acute Ischemic Stroke

Start date: July 28, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study was to evaluate the efficacy and safety of higher doses of monosialoganglioside GM1 injection in the treatment of patients with acute ischemic stroke.

NCT ID: NCT04951232 Completed - Stroke, Ischemic Clinical Trials

Clinical Study of Cinepazide Maleate Injection in the Treatment of Acute Ischemic Stroke

Start date: July 4, 2016
Phase: N/A
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled, parallel controlled, post marketing confirmatory clinical trial in Chinese patients with acute ischemic stroke. Objective to evaluate the efficacy and safety of cinepazide maleate injection compared with placebo in the treatment of patients with acute ischemic stroke.

NCT ID: NCT04889586 Completed - Stroke Clinical Trials

Hand MOtor Rehabilitation Using a EMG-biofeedback: a Cross-sectional Study

MORE
Start date: July 25, 2017
Phase: N/A
Study type: Interventional

Recovery of upper limb and hand gestures is fundamental for autonomy restoration after stroke. Innovative technologies are a valid support for the delivery of rehabilitation treatments. Embedding surface electromyographic (sEMG) into wearable devices, allows the customisation of rehabilitation exercises, based on the clinical profile of each patient.

NCT ID: NCT04835740 Completed - Clinical trials for Cerebrovascular Accident

Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke

Start date: October 5, 2020
Phase: N/A
Study type: Interventional

Hemiplegia is one of the most common sequelae of stroke. Stroke is the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen. The purpose of this study is to Determine the effect of Aerobic exercise training on Balance, Walking capacity and quality of life in sub-acute stroke.

NCT ID: NCT04825405 Completed - Stroke, Ischemic Clinical Trials

The Use of the Tip Stim Glove Device to Achieve Coordinated Movement of the Human Hand

Start date: July 10, 2019
Phase: N/A
Study type: Interventional

The study was to evaluate the use of the Tip Stim device to achieve coordinated movement and grip force in stroke patients under conditions of active and passive stabilization of the trunk.

NCT ID: NCT04770363 Completed - Stroke, Acute Clinical Trials

Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.

NCT ID: NCT04704635 Completed - Aging Clinical Trials

Trajectories of Post-stroke Multidimensional Health

NeuroAdapt
Start date: May 12, 2021
Phase:
Study type: Observational

Stroke is thought to cause disability immediately after stroke followed by a 3-to-6-month recovery period, after which disability levels are supposed to stabilize unless recurrent events occur. However, studies showed that post-stroke recovery is heterogeneous. While some stroke survivors quickly recover, others may show an accelerated accumulation of disability over time. The current prospective observational study will investigate trajectories of multidimensional functioning and self-rated health in the year after stroke. Particularly, the study aims to explore the relationship between trajectories of disability and self-rated health. Moreover, the study will focus on potential predictors of changes in disability and self-rated health, i.e., views on aging and psychological resilience. Patients will be recruited during their stay at the stroke unit and participate in a face-to-face interview and four follow-up telephone interviews in the post-stroke year.

NCT ID: NCT04693715 Completed - Stroke, Ischemic Clinical Trials

Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy

RESCUE
Start date: July 7, 2021
Phase: Phase 2
Study type: Interventional

A Phase II, randomized, blinded, placebo-controlled, parallel group study with patients experiencing a large vessel occlusion acute ischemic stroke who are selected for endovascular revascularization. Participants will be given a 48 h infusion of either 0.5 mL/kg/h RNS60 (up to a maximum of 60 mL/h), 1 mL/kg/h RNS60 (up to a maximum of 120 mL/h), or 1 mL/kg/h (up to a maximum of 120 mL/h) placebo (normal saline) starting within 30 minutes of consent after confirmation of candidacy for endovascular thrombectomy.

NCT ID: NCT04672148 Completed - Stroke, Ischemic Clinical Trials

Prognostic Factors and Mortality in Older Stroke Patients With Mechanical Thrombectomy

Start date: December 1, 2020
Phase:
Study type: Observational

The study focus on the elderly patient (older than 80 years of age) who had acute ischemic stroke and received mechanical thrombectomy. The investigators analyze different factors in the stage of before, between, after procedure and trying to figure out if there is any difference between the 30-day-mortality group versus non-30-day-mortality group.