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Aging clinical trials

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NCT ID: NCT05484739 Not yet recruiting - Aging Clinical Trials

Heat Waves and the Elderly - Cooling Modalities

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess how well cooling modalities work in reducing cardiovascular stress of the elderly to heat wave conditions

NCT ID: NCT05484661 Not yet recruiting - Aging Clinical Trials

Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults

BCAA
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Fatigue is a strong predictor of negative health outcomes in older adults. The research in this study will compared the effects of 8-weeks of branched chain amino acids (BCAAs: dietary supplements commonly taken to improve muscle growth and exercise performance) added to exercise on fatigue compared to exercise with a placebo (an inactive, harmless substance). BCAAs could have an impact on improving fatigue common in older adults, especially when exercising.

NCT ID: NCT05483465 Not yet recruiting - Aging Clinical Trials

The Effect of NAD Supplementation on Brain Vascular Health in Aging

Start date: September 2022
Phase: Phase 4
Study type: Interventional

Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to test whether NR can also improve brain health and memory.

NCT ID: NCT05482711 Not yet recruiting - Aging Clinical Trials

The Fuel and Rhythm (FAR) Phase 2 Study

Start date: September 2022
Phase: N/A
Study type: Interventional

Both fuel metabolism and circadian rhythms have emerged as important targets to improve cellular and mitochondrial health and ultimately affect function in older adults. Thus, the purpose of this study is to develop minimally invasive measures that will allow us to accurately assess and detect changes in fuel metabolism and circadian rhythms in older adults following time-restricted eating.

NCT ID: NCT05475236 Not yet recruiting - Aging Clinical Trials

Neural Underpinnings of Turning

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Older adults and stroke survivors often have difficulty performing complex walking tasks, due in part to changes in the brain. One task often overlooked is turning, which can lead to injury when performed poorly. The investigators will use non-invasive brain stimulation to assess brain activity and relate those observations to turning performance in older adults and stroke survivors.

NCT ID: NCT05471557 Not yet recruiting - Aging Clinical Trials

Pain and Motor Learning in Older Adults

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its retention in older adults. The investigators hypothesize that acute impairs retention of locomotor learning in young and older adults and that in older adults, these deficits are worsened and are related to the degree of normal age-related cognitive decline.

NCT ID: NCT05469516 Not yet recruiting - Aging Clinical Trials

Superficial MFU-V and Diluted Calcium Hydroxyapatite for the Improvement of Lower Face Skin Quality and Wrinkles

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Aging, genetics and environmental factors contribute to multiple changes on the surface of the skin. These present with pigmentation, volume loss, loss of elasticity and loss of collagen. Altogether, areas of the face becomes "crepey", with resulting rhytids and an obvious appearance of thin and fragile skin. These are typically dermal manifestations of elastin and collagen loss resulting in a collective term of loss of "skin quality". Current treatments to improve these changes involve the use of skincare, chemical peels, as well as more invasive repeated treatments such as microneedling and laser resurfacing. These commonly require repeated treatments and several days of downtime. More recently, treatment with a hybrid preparation of high and low-molecular weight complexes that are thermally cross-linked (Profhilo) has been suggested to stimulate collagen and elastin formation, thereby resulting in improvement in skin quality.

NCT ID: NCT05468905 Recruiting - Alzheimer Disease Clinical Trials

China Longitudinal Aging and Cognitive Impairment Study

CLACIS
Start date: January 10, 2021
Phase:
Study type: Observational

This is a multi-center longitudinal study that consists of five cohorts: cognitive normal aging (CN), Subjective cognitive impairment (SCI), mild cognitive impairment (MCI), Alzheimer's disease (AD) and vascular cognitive impairment (VCI). The goals of this study are as follow: 1.To establish longitudinal cohort study database containing comprehensive epidemiological data, neuropsychological test data, laboratory parameters, image data and biological samples. 2. To determine the risk factors of AD and other dementias. 3. To explore the conversion rates from CN to SCI, MCI or AD and the risk factors as well as biomarkers for the progression from CN to SCI, MCI or AD. 4. To explore and validate blood, CSF, urine, imaging and other biomarkers for the early detection and progression of AD.

NCT ID: NCT05462626 Not yet recruiting - Quality of Life Clinical Trials

A Telehealth Lifestyle Intervention for Community-Dwelling Older Adults

Start date: July 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if an occupational therapy lifestyle program for community-dwelling older adults delivered individually through a telehealth platform can produce comparable outcomes in health-related qualify of life and occupational performance as found in studies that used a longer duration and group intervention.

NCT ID: NCT05456971 Completed - Aging Clinical Trials

Evaluation of the Long Term Efficacy and Tolerability of ART FILLER® Volume and Lips

AF2
Start date: September 12, 2016
Phase: N/A
Study type: Interventional

The function of injectable fillers for the treatment of dermal contour deformities is to smooth dermal depressions formed by the loss of volume. These fillers (also known as soft tissue augmentation devices) can restore the age-related volume loss of the face, balance the disproportions or correct topographical anomalies. Art Filler® Volume and Art Filler Lips are two hyaluronic-based fillers. Both contain 0.3% lidocaine hydrochloride for its anaesthetic properties. The difference between the two devices lies in their viscosity, which must be adapted for the regions being treated and to restoring facial volumes. Midface for Art Filler® Volume and Lips for Art filler® Lips. On this background, a study is conducted to evaluate the long term efficacy and tolerability of Art Filler® Volume and Art Filler® Lips. It is a prospective, non-comparative, multicentre study with long term evaluation (18 months) of the tolerability and assessment of the efficacy of two devices containing hyaluronic acid intended for filling of lines and restoring volume to the face and lips.