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Cardiovascular Disease clinical trials

View clinical trials related to Cardiovascular Disease.

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NCT ID: NCT04258345 Withdrawn - Clinical trials for Cardiovascular Disease

Artificially Sweetened Beverage Feeding Study

Start date: July 2021
Phase: N/A
Study type: Interventional

The aims of the study are to conduct a pre- and post- two week feeding study of artificial sweetened beverage consumption in middle-aged women. The study will also compare metabolic profiles before and after artificially sweetened beverage consumption.

NCT ID: NCT02871310 Withdrawn - Clinical trials for Cardiovascular Disease

Vasoactive Effects of IQP-AS-118 in Healthy Individuals

Start date: March 2018
Phase: N/A
Study type: Interventional

The main objective of this study is to evaluate the benefit of IQP-AS-118 on the vasoactive effects in healthy subjects.

NCT ID: NCT02866448 Withdrawn - Clinical trials for Cardiovascular Disease

Impact of isoQUercetin and Aspirin on Platelet Function

QUAP
Start date: August 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of acute isoquercetin supplementation, aspirin, and isoquercetin/aspirin combination on platelet aggregation, blood pressure and vasculat stiffness (eg digital volume pulse), as well as investigating the plasma accumulation and urine excretion profiles of quercetin.

NCT ID: NCT02838355 Withdrawn - Clinical trials for Cardiovascular Disease

Employing End Tidal Capnography in Continuous Flow Ventricular Assist Device Patients

Start date: October 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to explore how the End Tidal Carbon Dioxide monitoring via nasal cannula (ETCO2-NC) device may allow for earlier detection of respiratory complications. This device will detect the amount of carbon dioxide exhaled with each breath and may better predict high levels of this than traditional monitoring. This may reduce the number and severity of respiratory issues. A convenience sample of 60 participants either scheduled for continuous flow left ventricular assist device (CF-LVAD) implant or who have been readmitted to an ICU with a CF-LVAD will be recruited and randomized to usual care or usual care plus ETCO2-NC throughout their stay in the ICU.

NCT ID: NCT02517671 Withdrawn - Clinical trials for Cardiovascular Disease

Impact of Enhanced External Counterpulsation (EECP) on VO2 MAX

Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of 35 EECP sessions on cardiopulmonary training performance in healthy volunteers. Data from this study will be used to generate sample size and power calculations for feasibility of future EECP studies. The results of this study could provide evidence that can help active duty and Department of Defense beneficiaries optimize physical conditioning, endurance and overall health.

NCT ID: NCT02507323 Withdrawn - Clinical trials for Cardiovascular Disease

Ticagrelor vs. Prasugrel Effects on Infarct Size

TIPRIS
Start date: February 2016
Phase: Phase 2
Study type: Interventional

This study has been designed as a randomized, double-blind trial to provide definitive evidence on the effects of ticagrelor and prasugrel on myocardial salvage in patients with anterior ST Segment Elevation Myocardial Infarction (STEMI) undergoing primary Percutaneous Coronary Intervention (PCI). This study will also measure the effects of ticagrelor vs. prasugrel on secondary endpoints listed above. This study design aims to test the hypothesis that ticagrelor will reduce myocardial infarct size as a proportion of the ischemic area at risk when compared to prasugrel.

NCT ID: NCT02473705 Withdrawn - Clinical trials for Cardiovascular Disease

Pathways to Improving Functional Capacity in Older Patients With Chronic Kidney Disease and Cardiovascular Disease

CKD&CAD
Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of this research study is to study the effect of fish oil and bicarbonate (baking soda) on exercise. In this study fish oil, bicarbonate or both will be compared to placebo to see if study participants increase exercise capacity.

NCT ID: NCT02421549 Withdrawn - Heart Failure Clinical Trials

Remote Interrogation in Rural Emergency Departments

REM RED
Start date: December 2014
Phase: Phase 4
Study type: Interventional

A retrospective, multi-center, proof-of-concept study to evaluate the use of remote monitoring in rural emergency departments to decrease time to treatment decision for pacemaker and defibrillator patients using the St Jude Medical [email protected] transmitter. The purpose of the study is to determine if utilization of remote monitoring technology in a rural emergency department may improve patient care. Up to 10 rural ED sites will enroll a total of 200 patients. One hundred patients will be in the remote monitoring group comprised of patients with SJM devices compatible with the unpaired transmitter and 100 patients will be in the usual medical care group comprised of patients with SJM devices that are not compatible with the unpaired transmitter or that have a competitor's device.

NCT ID: NCT02379403 Withdrawn - Clinical trials for Cardiovascular Disease

Effects of Tart Cherry and Aroniaberry Supplementation on Endothelial Function and Cardiovascular Measures in Healthy Older Adults: Interactions With Genotype and Proteome

Start date: February 19, 2015
Phase: N/A
Study type: Observational

Background: - Heart disease is the leading cause of death and disabilities in the United States. Diets high in fruits and vegetables may reduce the risk of heart disease. Fruits, including red tart cherries and purple aroniaberries, may be especially beneficial. Researchers want to know how tart cherry and aroniaberry extracts affect heart health. Objective: - To study the benefits of tart cherry and aroniaberry extract on vascular function and other measures. These include inflammation, oxidation, and cholesterol. Eligibility: - Men and post-menopausal women ages 55 70 in good health and with normal or slightly high blood pressure or cholesterol. Design: - Participants will be screened with a physical exam, medical history, and blood tests. - Participants will have 6 visits. They will have blood taken at every visit. - Visit 1: - Blood vessel tests. Participants will lie down. Heart rhythm will be monitored. A device will be placed on the upper arm, and pictures of blood vessels will be taken. - A blood pressure cuff will be tightened around the lower arm for 5 minutes. - Cardio-Ankle-Vascular Index (CAVI). Blood pressure cuffs will be placed on both arms and legs. They will be tightened with air at the same time for a few minutes. - Participants will be assigned to one of three groups. For 3 weeks each, in random order, they will take: aroniaberry capsules, tart cherry capsules, placebo capsules, and no capsules. - Participants will answer questions online about their eating and exercise. - Participants will be keep a record of what they eat for a few periods. They will come for a study visit every 3 weeks through week 15.

NCT ID: NCT02186353 Withdrawn - Diabetes Clinical Trials

Processing Responses of Grains (PRO-Grains) Study

Start date: September 2014
Phase: N/A
Study type: Interventional

The primary objective of this pilot study will be to examine the effects of consuming whole grains, differing in the degree of processing, on insulin sensitivity and other cardiometabolic risk factors. The overall aim will be to assess feasibility of the test diets and to generate preliminary data.