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Cancer clinical trials

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NCT ID: NCT05010239 Completed - Cancer Clinical Trials

The Immediate Effect of Mindfulness-Based Supportive Therapy on Palliating Suffering in Palliative Care Cancer Patients

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The was a parallel group, single-blinded, randomized controlled trial comparing the effectiveness of 30-minute mindfulness-based supportive therapy versus supportive listening in reducing suffering among patients with cancer. This study was conducted in the University Malaya Medical Centre, from 1st august 2020 to 31 December 2020.

NCT ID: NCT05008497 Not yet recruiting - Cancer Clinical Trials

Cancer and Literacy in Health

CaLiS
Start date: September 2021
Phase:
Study type: Observational

Validation in French of a psychometric tool for measuring health literacy in the field of cancer

NCT ID: NCT05002842 Completed - Cancer Clinical Trials

Implementation of Mind-Body Practices in an Online Community of Caring (CaringBridge)

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

CaringBridge (CB) is an online health community for people undergoing challenging health journeys. This platform provides an opportunity for individuals and their caregivers to rally support for a loved-one during a health journey. CaringBridge offers the opportunity for expressive writing through journal entries, wellbeing resources, participant health journey stories, and practical scheduling and communication tools to support community, healing, and wellbeing. Loving Kindness Meditation (LKM) is a systemized mind-body approach developed to increase loving acceptance and has been shown to increase resilience in the face of adversity. The aim of this study is to better understand how mind-body practices, like LKM, impact adult CB users

NCT ID: NCT05001009 Enrolling by invitation - Cancer Clinical Trials

Goals of Care Conversations Study

LSTDI
Start date: September 13, 2022
Phase: N/A
Study type: Interventional

The long term goal is to improve quality of care in Veterans with serious illnesses by aligning medical care with Veterans' goals and values. The objective of this study is to use a sequentially randomized trial to determine what implementation strategies are effective to increase early, outpatient goals of care conversations. The study will use interviews with and surveys of medical providers, patients, and caregivers, along with medical record data. This work is significant because it tests ways Veterans can express their goals and preferences for life sustaining treatments and have them honored.

NCT ID: NCT05000372 Recruiting - Cancer Clinical Trials

68Ga-grazytracer PET/CT of Tumor Responses to Immunotherapy

Start date: September 22, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the safety and clinical predictive value of 68Ga-grazytracer in subjects with non-small cell lung cancer, melanoma or lymphoma receiving immunotherapy.

NCT ID: NCT04999176 Recruiting - Cancer Clinical Trials

Venous Thromboembolism Prophylaxis After Gynecological Pelvic Cancer Surgery With Rivaroxaban vs Enoxaparin

VALERIA
Start date: October 22, 2020
Phase: Phase 3
Study type: Interventional

The Valeria trial will provide high-quality evidence regarding the efficacy and safety of oral rivaroxaban in thromboprophylaxis after gynecological pelvic cancer surgery in comparison with standard parenteral enoxaparin.

NCT ID: NCT04995848 Recruiting - Cancer Clinical Trials

Telepalliation - Digital Platform for Patients in Palliation and Their Relatives

Start date: May 26, 2021
Phase: N/A
Study type: Interventional

This project has focus on patients in palliation testing a digital platform TelePal.dk.

NCT ID: NCT04994730 Recruiting - Cancer Clinical Trials

Exenteration: Quality of Life Study and Rehabilitation Rate According to the Reconstruction Technique (ETRE)

ETRE
Start date: May 25, 2021
Phase:
Study type: Observational

Prospective monocentric quality of life study. Including all patients who have been exentered at the Institut Curie Paris, from January 2004 to December 2019, proposing to compare the reported quality of life of patients according to the reconstruction technique they have undergone. The sponsor will evaluate the quality of life of our patients by means of two validated questionnaires, in French, in the context of ENT surgery: the FACT-G and FACT-MBIS questionnaires.

NCT ID: NCT04994093 Recruiting - Cancer Clinical Trials

Creating an Innovative AI-based Technology TCRact for Designing and Optimizing T-cell Receptors (TCR) for Use in Cancer Immunotherapies

Start date: October 6, 2021
Phase:
Study type: Observational

The PROJECT OBJECTIVE is to create an innovative AI-based (Artificial Intelligence) IN SILICO TECHNOLOGY for the design and optimization of T-cell receptors (TCRs) capable of recognizing specific tumor antigens presented on Human Leukocyte Antigen (HLA). The technology will be based on bioinformatics (including molecular modelling) and artificial intelligence (including predictive, generative and optimization models). PROJECT TASKS are dedicated to the implementation of individual technological components (including the database necessary for their preparation) and to performing IN VITRO evaluation rounds to optimize the technology. Integration, within an IN SILICO TECHNOLOGY, of processes which currently require huge amounts of in vitro laboratory experiments that are necessary for bringing new TCR-based cancer immunotherapies into clinical trials: - finding appropriate TCRs targeting cancer neoantigen presented on a HLA molecule (pHLA) - testing for potential TCR toxicity (targeting self antigens presented on healthy tissues) - optimization of pHLA:TCR binding affinity and toxicity.

NCT ID: NCT04988490 Recruiting - Cancer Clinical Trials

Quantification of Cannabinoids and Comparison to Post-Surgical Pain Medication Requirements and Surgical Outcomes

Start date: September 22, 2021
Phase:
Study type: Observational

To determine how daily cannabis use affects surgical outcomes.