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Cancer clinical trials

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NCT ID: NCT06224894 Not yet recruiting - Cancer Clinical Trials

The Effect of Music Therapy on Nausea, Vomiting and Anxiety Levels in Children

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This study will be conducted with a randomized controlled study model to examine the effect of music therapy on nausea, vomiting and anxiety levels in children diagnosed with oncological cancer receiving cisplatin. The research is planned to be carried out at Dokuz Eylül University Nevvar-Salih İşgören Children's Hospital Pediatric Hematology-Oncology Clinic between December 2023 and December 2024. There is no application for music therapy in the operation of this hospital and clinic.

NCT ID: NCT06213298 Not yet recruiting - Depression Clinical Trials

Effect of Kava on Anxiety and Stress in Cancer Survivors

Start date: June 1, 2024
Phase: Early Phase 1
Study type: Interventional

This is a pilot, two-arm, randomized, blinded, placebo-controlled cross-over clinical trial to study the safety and effect of 14 days of kava on anxiety and physiologic stress in survivors of cancer and its treatment. Participants will be randomized to take either kava first or placebo first. Kava 75 mg or placebo will be taken three time daily (TID) for 14 days (Period 1), followed by a washout period of 14-28 days. Thereafter, the participant will take either placebo or kava TID for 14 days (Period 2), whichever he/she did not take in Period 1.

NCT ID: NCT06209996 Not yet recruiting - Cancer Clinical Trials

A Weight Management Intervention for Overweight Chinese Cancer Survivors

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

This study aims to conduct a feasibility trial to examine the feasibility and acceptability of conducting a randomized controlled trial that evaluates the effect of the weight management intervention on anthropometric measures (body weight and BMI), dietary quality, physical activity levels, physical and psychosocial functioning, self- efficacy for weight loss and quality of life.

NCT ID: NCT06206941 Not yet recruiting - Cancer Clinical Trials

IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

IMPACT-C
Start date: May 30, 2024
Phase:
Study type: Observational

The purpose of this research is to assess how patients with cancer being treated with Immune Checkpoint Inhibitors (ICI) manage symptoms related to cancer and/or its treatment. Patients use a variety of ways to manage symptoms including traditional and alternative treatments including cannabis, acupuncture, etc. This research will have an important impact on our knowledge of cancer symptom management, and ultimately improve patient care and safety. Participants will complete online surveys and 7 days of ecological momentary assessments at 0, 1, 2, 4, 6, 9 and 12 month to compare the cannabis users and non cannabis users symptoms.

NCT ID: NCT06184256 Not yet recruiting - Cancer Clinical Trials

BfedBwell Optimization Pilot

Start date: July 2024
Phase: N/A
Study type: Interventional

Using the Multiphase Optimization Strategy (MOST) framework, an engineering-based approach to efficiently and systematically develop, optimize, and evaluate behavioral interventions, this study will test three components: (1) 1:1 counseling with a registered dietitian, (2) behavioral skills development, and (3) group support for delivery alongside a core nutrition curriculum within a clinical exercise oncology program.

NCT ID: NCT06183151 Not yet recruiting - Cancer Clinical Trials

Capillary-Venous Paired Collection

CaVe
Start date: February 2024
Phase:
Study type: Observational

This study is recruiting participants to donate 2 capillary blood samples to be tested on the investigational system. At the same time, remnant routine blood samples used for Complete Blood Count (CBC) testing from the same participants will be tested on the investigation system. The participants' routine CBC results analyzed on the gold standard laboratory analyzer (comparator) will be collected and compared against the results obtained from the testing of capillary blood samples and remnant blood samples on the investigational system. The participants' involvement in the study is only for the duration of collecting the blood samples. No follow-up is anticipated. The results from the investigational system is for research use only and will not inform or change the participants' treatment or care.

NCT ID: NCT06181344 Not yet recruiting - Cancer Clinical Trials

Implementation and Evaluation of a Fear of Cancer Recurrence Screening, Referral and Management Program

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the process and outcomes of an implementation program designed to implement fear of cancer screening, referral and management into routine cancer care clinics, using a stepped-wedge cluster randomized controlled trial.

NCT ID: NCT06181331 Not yet recruiting - Cancer Clinical Trials

The Effect of a Stepped-care Metacognition-based Intervention on Managing Fear of Cancer Recurrence

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

A sequential multiple-assignment randomized controlled trial (SMART) will be used to assess the effect of an adaptive stepped-care intervention on FCR in cancer survivors with subclinical levels of fear of cancer recurrence.

NCT ID: NCT06156800 Not yet recruiting - Cancer Clinical Trials

Is Radiation-before-pathology a Feasible Approach in the Palliative Oncology Setting? A Pragmatic Clinical Trial

RT-NOW
Start date: May 1, 2024
Phase:
Study type: Observational

When a doctor suspects cancer, often a biopsy is taken for testing to confirm if cancer is present. Usually, doctors would wait for the results of a biopsy before delivering radiation, but this may lead to a patient having to wait for a treatment that he or she urgently needs. With long wait times for biopsies in Canada, this may lead to symptoms and risks of complications from cancer in the meantime. Therefore, this study is being done to answer the following question: Is it safe and feasible to deliver radiation before obtaining a biopsy in a carefully selected group of patients who urgently need radiation treatment.

NCT ID: NCT06152926 Not yet recruiting - Cancer Clinical Trials

Physical Activity and Exercise in Cancer Immunotherapy Treatment

Start date: December 4, 2023
Phase:
Study type: Observational

People who are diagnosed with a cancer commonly experience symptoms that affect day-to-day life, including muscle weakness, pain, tiredness and fatigue. These consequences can make it hard for people to tolerate their medical treatments. It is well known that regular physical activity or planned exercise can help with these symptoms and significantly improve physical and mental health during cancer treatment. Recent animal studies suggest that exercise training can also reduce the number of cancer cells. For example, exercise training in mice produces more immune cells in the tumour. These immune cells in the tumour contribute to the destruction and reduction of the size of the tumour and are a vital component of effective immunotherapy (cancer treatment that helps your immune system fight cancer). In humans, exercise training and the effect on the immune response in tumours are less understood and is a new area being explored. However, we are aware that most people diagnosed with a cancer are not physically active, and especially not during the treatment period. The aim of this study is to understand the experiences and perceptions of physical activity and exercise in those with cancer receiving immunotherapy treatment (such as immune check point inhibitors (ICI). This will help us to create new practices or change practices to help those with cancer to partake in physical activity and exercise when on treatment. Participants consenting to take part in the study will be individually interviewed through a semi-structured interview.