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Stroke clinical trials

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NCT ID: NCT01535274 Completed - Stroke Clinical Trials

Ventilation Strategies, Anesthetic Techniques and Cerebral Oxygenation in the Beach Chair Position

Start date: September 2012
Phase: N/A
Study type: Interventional

The seated or "beach chair" position during surgery and general anesthesia decreases brain oxygen levels and can result in stroke. As such, poor neurological outcome following beach chair positioning is a growing concern. In the proposed study the investigators test the hypothesis that changes in ventilation strategy and anesthetic technique can affect cerebral oxygenation in anesthetized patients in the beach chair position.

NCT ID: NCT01529723 Withdrawn - Stroke Clinical Trials

Validity of a New Stroke Dysphagia Screening Tool

Start date: February 2012
Phase: N/A
Study type: Observational

Dysphagia or swallowing difficulty is common after stroke occurring in 25-78% of stroke survivors depending on the anatomic location of the stroke and the diagnostic test used. There are no universally accepted methods for doing a screen test at the bedside in the immediate setting after stroke. This study will assess the reliability of a bedside screen in terms of reproducibility of results between 2 independent screeners and in comparison to a fiberoptic study done by a speech language pathologist.

NCT ID: NCT01528462 Completed - Stroke Clinical Trials

Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke

SMARTIES
Start date: October 2011
Phase:
Study type: Observational

The aim of the investigators was to determine whether the immediate management of any detected sleep disorders can improve outcomes in patients who have had a transient ischemic attack (TIA) or minor stroke. This group of patients is at high risk for having a recurrent stroke or TIA, and the investigators would like to investigate new ways of preventing potentially avoidable events. The treatment of sleep disorders immediately after a stroke or TIA may prove to be a novel method of avoiding future strokes and improving outcomes.

NCT ID: NCT01527240 Completed - Stroke Clinical Trials

Neuroprotection Impact of Cyclosporin A in Cerebral Infarction

CsAStroke
Start date: October 2009
Phase: Phase 2
Study type: Interventional

The main objective of this study is to determine whether a single injection of CsA after intravenous thrombolysis can significantly decreased the volume of cerebral infarction at day 30 ± 15 assessed with Flair MRI. Secondary objectives are to determine whether a single injection of CsA after intravenous thrombolysis is safe and effective regarding to death and disability.

NCT ID: NCT01525979 Completed - Clinical trials for Cerebrovascular Accident

Comparative Efficacy Research of Uni- vs Bi-lateral Arm Training Poststroke

Start date: January 2011
Phase: N/A
Study type: Interventional

This proposed project aims to - compare the effects of dose-matched unilateral vs bilateral vs unilateral combined with bilateral upper limb rehabilitation based on task-related practice - compare the effects of unilateral vs bilateral training based on robot-assisted devices - study the predictors of treatment outcomes and clinimetric properties of the biomechanical measures

NCT ID: NCT01525290 Completed - Stroke Clinical Trials

Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke

WAKE-UP
Start date: September 2012
Phase: Phase 3
Study type: Interventional

WAKE-UP is an investigator initiated European multicenter randomized controlled clinical trial of MRI based thrombolysis in acute stroke patients with unknown time of symptom onset, e.g. due to recognition of stroke symptoms on awakening. Objective of WAKE-UP is to prove efficacy and safety of MRI-based intravenous thrombolysis with Alteplase in patients waking up with stroke symptoms or patients with otherwise unknown symptom onset.

NCT ID: NCT01523925 Withdrawn - Clinical trials for Cerebrovascular Accident

Combined Behavioral Approaches With Functional Electrical Therapy in Stroke Rehabilitation

Start date: January 2012
Phase: N/A
Study type: Interventional

This project attempts to perform a randomized controlled trial to verify the efficacy and motor control mechanism of the proposed combined functional electrical therapy with distributed constraint-induced therapy or with robot-assisted Bilateral training.

NCT ID: NCT01521351 Recruiting - Stroke Clinical Trials

Natural History of Carotid Atherosclerosis

Start date: January 2012
Phase:
Study type: Observational

A prospective study of 700 patients with coronary artery disease will undergo non invasive evaluation of their carotid arteries by ultrasound and microwave radiometry. The patients will be followed up for 3 years and their outcome regarding the cardiovascular events (death, cardiac events, cerebrovascular events) will be recorded

NCT ID: NCT01521234 Completed - Stroke Clinical Trials

Using Wireless-technology for Feedback of Daily Walking Activity Post-stroke

Start date: October 2012
Phase: N/A
Study type: Interventional

Regaining independent walking is the top priority for individuals recovering from stroke. Thus, physical rehabilitation post-stroke should focus on improving walking function and endurance. However, the amount of walking completed by individuals with stroke attending rehabilitation is far below that required for independent community ambulation. There has been increased interest in accelerometer-based monitoring of walking post-stroke. Walking monitoring could be integrated within the goal-setting process for those with ambulation goals in rehabilitation. The purpose of this study is to determine the effect of accelerometer-based feedback of daily walking activity during rehabilitation on the frequency and duration of walking post-stroke.

NCT ID: NCT01520636 Terminated - Rehabilitation Clinical Trials

Active MOBility Early After Stroke : What Should be the Best Physiotherapy Early After Stroke ?

AMOBES
Start date: July 2012
Phase: N/A
Study type: Interventional

This study is designed to observe the respective effects of 2 types of physiotherapy early after a cerebral stroke. The hypothesis is that an intensive physiotherapy early delivered (Day 2 to D15) after a stroke could induce faster motor control recovery than a conservative physiotherapy aiming at preventing complications.