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Stroke clinical trials

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NCT ID: NCT02773888 Suspended - Stroke Clinical Trials

An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring Device

Start date: December 2015
Phase: N/A
Study type: Interventional

Invasive intracranial pressure (ICP) monitoring is highly effective, but involves risks. HS-1000 measures ICP non-invasively by assessing the acoustic properties of the patient's head. HS-1000 device, a proprietary non-invasive ICP monitor, is expected to safely and accurately monitor ICP with minimal discomfort to patients, and provide information about normal or elevated ICP levels to the physicians.

NCT ID: NCT02772809 Terminated - Stroke Clinical Trials

Usability Testing of Affordable Haptic Robots for Stroke Therapy

Theradrive
Start date: March 2014
Phase: N/A
Study type: Interventional

Stroke survivors with hemiplegia will be evaluated by rehabilitation professionals and asked to perform a battery of assessments to test the viability and usability of a force-feedback robot that adapts to each individual subject's performance. Subsequently, they will be asked to complete post-assessment questionnaires that provide feedback to the researchers on their observations and thoughts about the therapy devices.

NCT ID: NCT02772510 Recruiting - Stroke Clinical Trials

Upper Extremity Rehabilitation Using Game Rehabilitation System With Functional Electrical Stimulation for Stroke Patients

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of the present study was to investigate the effects of game-based virtual reality rehabilitation combined with functional electrical stimulation on distal upper extremity function, and compare the findings to those of functional electrical stimulation in stroke survivors.

NCT ID: NCT02772484 Completed - Stroke Clinical Trials

An Evaluation of Non-invasive ICP Monitoring in Patients Undergoing Routine Care

Start date: April 2016
Phase: N/A
Study type: Interventional

The HS-1000 device, an investigational intracranial monitoring device, has the potential to safely and quickly diagnose and assess stroke (and potentially other neurologic conditions) with minimal discomfort to patients. HS-1000 has the capability to establish cerebral hemodynamic measurements in suspected stroke within minutes, assist with appropriate management of stroke, and also provide an objective diagnostic tool for clinicians to monitor recovery.

NCT ID: NCT02772445 Completed - Stroke Clinical Trials

Stroke Caregiver Empowerment

STROKE-CARE
Start date: April 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to refine STROKE-CARE for caregivers and explore changes in caregiver and care-recipient outcomes

NCT ID: NCT02770300 Terminated - Stroke Clinical Trials

Effect of Personalized Robotic Therapy

Start date: May 2016
Phase: N/A
Study type: Interventional

The primary goal of this project is to test the safeness and clinical effectiveness of a novel exoskeleton for the upper limb (Arm Light Exoskeleton Rehab Station, ALEx RS) developed at Wearable Robotics srl, for the force assistance of stroke patients during robotic-rehabilitation. The secondary study aim is to design and test an automatic personalized robot-based upper limb motor rehabilitation protocol targeting the specific kinematic performance of each patient. Finally, the study also aims to define the "neuro-biomechanical state" of the patient and its evolution during the therapy by studying cortical signals and muscular synergies. This information will be used to improve the personalization of the robotic treatment by targeting not only the motor performance but also the cerebral and muscular activity of the patient. The study is longitudinally designed in order to test the safeness and clinical effectiveness of ALEx RS over time, and to monitor the clinical effectiveness of the automatic personalized robotic therapy from the beginning until the end of the treatment. Moreover, in order to estimate the long-term clinical effectiveness of the treatment, the assessment methods proposed in the clinical trial will be repeated one month after the end of the treatment.

NCT ID: NCT02769871 Terminated - Stroke Clinical Trials

NICE: NeuroImaging in Cessation Education

Start date: January 2017
Phase: N/A
Study type: Interventional

The investigators aim to examine the effect on smoking cessation rate by showing stroke patients who are active smokers images of their strokes.

NCT ID: NCT02769338 Completed - Stroke Clinical Trials

Protocol-guided Rapid Evaluation of Veterans Experiencing New Transient Neurological Symptoms

PREVENT
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

This program will seek to implement a quality improvement program to improve the care of Veterans with TIA or minor stroke at 6 Veteran Health Administration Hospitals. The investigators will evaluate the implementation and effectiveness of the quality improvement program.

NCT ID: NCT02768922 Completed - Stroke Clinical Trials

Aphasia Telerehabilitation

AT
Start date: May 3, 2016
Phase: N/A
Study type: Interventional

This study aims at contributing with scientific evidence to the field of aphasia telerehabilitation. In Norway today, there is an unmet need for language training in post stroke aphasia and not all patients are offered language training. Early start of aphasia rehabilitation and satisfying intensity do not seem to be standard clinical practice. Language training by telemedicine could improve this situation, and this study seeks to answer the question whether aphasia rehabilitation delivered by videoconference can improve language function in aphasia post stroke.

NCT ID: NCT02768571 Completed - Stroke Clinical Trials

Effects of Cerebrolysin Combined With Rehabilitation on Motor Recovery in Stroke

Start date: March 14, 2016
Phase: Phase 4
Study type: Interventional

This study, E-COMPASSII is a phase IV clinical trial designed as a multicenter, randomized, double-blind, placebo-controlled, parallel-group study. This study will enroll 80 subacute stroke patients with severe motor involvement. Primary objective is to demonstrate the efficacy of porcine brain peptide to improve motor recovery measured by the improvement ratio of Fugl-Meyer assessment ((score of FMA after 3 weeks - score of FMA at baseline) / score of FMA at baseline) in patients with subacute stroke. Secondary objectives are to evaluate the safety profile of cerebrolysin and to test the hypothesis that subacute stroke patients with severe motor involvement randomized to administration of Cerebrolysin combined with rehabilitation for 3 weeks show better outcome on global function (Korean version Modified Barthel Index, K-MBI), severity of stroke (National Institute of Health Stroke Scale, NIHSS), cognitive function (Korean Version of Mini-Mental State Exam, K-MMSE; Korean version Montreal Cognitive Assessment, K-MoCA), upper limb function (Action Research Arm Test, ARAT; Box and block test, B&B) and neuroplasticity measure (resting-state functional MRI(rsfMRI), diffusion tensor image(DTI), and motor evoked potential(MEP)) at 3 months after stroke.