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Pain clinical trials

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NCT ID: NCT03376308 Completed - Pain Clinical Trials

Evaluation of the Effect of Venous Diameter Measurement by Ultrasonography on Pain and Withdrawal Response

VDIAMETER
Start date: June 1, 2017
Phase: N/A
Study type: Observational

During general anesthesia, intravenous (IV) medications can disrupt the patient's comfort by causing a pain sensation or a withdrawal response in the heart. Propofol and rocuronium are among the most common causes of this condition. In recent years, the use of ultrasonography (USG) in anesthesia has become widespread with the rapid advancement of technology. The use of the patient's head is a non invasive method. This study is aimed to evaluate whether the size of the venous diameter assessed by ultrasonography in our study is an effect on pain and withdrawal response after drug injections.

NCT ID: NCT03376178 Completed - Pain Clinical Trials

Catheter Orifice Configuration (Six-hole Versus End-hole) on Post-operative Analgesia After Total Knee Arthroplasty.

Start date: May 2014
Phase: N/A
Study type: Interventional

Multiorifice catheters have been shown to provide superior analgesia and significantly reduce local anesthetic consumption compared with end-hole catheters in epidural studies. This prospective, blinded, randomized study tested the hypothesis that, in continuous femoral nerve block (CFNB) under ultrasound guidance, multiorifice catheter would reduce local anesthetic consumption at 24h compared with end-hole catheter.

NCT ID: NCT03374982 Completed - Pain Clinical Trials

Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children

Start date: February 19, 2018
Phase: N/A
Study type: Interventional

Title: Effect of the DentalVibe injection system on pain during local anesthesia injections in children. Purpose: The purpose of this study is to compare self-reported pain scale measurements using the Wong-Baker FACES pain rating scale from an experimental group (local anesthesia injection with DentalVibe system) and a control group (traditional local anesthesia injection with DentalVibe system turned off) in children. Eligibility: Children age 5-11 years old who require local anesthesia for bilateral dental treatment at University of Nebraska Medical Center (UNMC) pediatric dental clinic. Children must understand and speak English. Interventions and evaluations: Each patient will have two separate restorative appointments where the DentalVibe will be used during local anesthetic injections. One appointment the DentalVibe will be turned on and one appointment the DentalVibe will be turned off. After each injection the child will be shown the Wong Baker FACES Pain Rating Scale and asked to pick a face associated with their level of hurt during the injection. Follow-up: All children will be followed up with any necessary recommended dental treatment.

NCT ID: NCT03374592 Completed - Pain Clinical Trials

Volumetric Intensity Modulated Arc Therapy vs. Conventional Radiotherapy for Cancer Pain

Start date: July 7, 2014
Phase: N/A
Study type: Interventional

This study compares the use of conventional radiotherapy technique with volumetric intensity-modulated radiotherapy (VMAT) in the treatment of painful cancer metastases. Half of the patients will receive radiotherapy using a conventional technique, while the other half will receive their treatment using a the VMAT technique.

NCT ID: NCT03374059 Completed - Pain Clinical Trials

Exercise and Life Modification for Text-Neck

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Objectives: The purpose of the study was to investigate the effects of exercise and life modification on pain and disability in "text neck". Methods: Eighty-five participants were randomly divided into three groups: Exercise (n=29), Exercise+Life modification (n=28), and Control Group (n = 28). Pain intensity during rest, activity, and at night was evaluated with Visual Analogue Scale (VAS) and functional assessment was done by using Neck Disability Index at the beginning and at the end of 4 weeks.

NCT ID: NCT03368326 Completed - Brain Injuries Clinical Trials

Use of Critical-Care Pain Observation Tool and Bispectral Index for Detection of Pain in Brain Injured Patients

Start date: June 9, 2015
Phase: N/A
Study type: Observational

Brain injured patients are at high risk of pain due to the illness itself and a variety of nociceptive procedures in intensive care unit. Since the disorder of consciousness, speech, and movement, it is usually difficult for them to self-report the presence of pain reliably. The Critical-Care Pain observation Tool (CPOT) has been recommended for clinical use in the critically ill patients when self-report pain is unavailable. Besides, it seems that the bispectral index (BIS), a quantified electroencephalogram instrument, can be used for pain assessment along with the CPOT tool in some nonverbal critical ill patients (e.g., intubated and deep sedation). However, the validity and reliability of CPOT and BIS for pain assessment in brain injured patients are still uncertain so far. So the aim of this research is to investigate the value of CPOT and BIS for pain evaluation in this specific patient group.

NCT ID: NCT03357029 Completed - Neuropathic Pain Clinical Trials

Neuromodulation in Patients With Painful Chronic Pancreatitis

Start date: January 11, 2018
Phase: N/A
Study type: Interventional

The purpose of this trial is to explore if a novel vagal neuromodulation approach provides analgesic benefit through central mechanisms in patients with chronic pancreatitis

NCT ID: NCT03356145 Completed - Pain Clinical Trials

12 Versus 20 mL PCB for D&E Cervical Prep

Start date: January 1, 2017
Phase: Phase 4
Study type: Interventional

More research is needed to investigate methods of pain control for cervical preparation for abortion procedures. Women report pain with paracervical block injection as well as with osmotic dilator placement. This study seeks to compare a 12 mL, 2-site 1% plain lidocaine paracervical block for pain control during cervical preparation (osmotic dilator insertion) for Dilation and Evacuation (D&E) to a 20 mL 1% lidocaine 2-site paracervical block.

NCT ID: NCT03353233 Completed - Pain Clinical Trials

Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.

Start date: May 3, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to learn if using an Interspace between the Popliteal Artery and Capsule of the Knee (iPACK) injection technique (also called a "nerve block") that numbs the nerves going to the back part of the knee to aid in physical therapy after surgery. The iPACK technique uses a numbing solution (local anesthetics) that is injected behind the knee to reduce pain and to help straighten the knee. This block may affect movement in the leg and make the legs weak, but thing is rare. A few institutions use the iPACK block for patients having total knee replacements, with the hope of providing good pain relief combined with improved mobility after surgery.

NCT ID: NCT03351075 Completed - Pain Clinical Trials

Effectiveness of a Modern Educational Intervention in Breast Cancer Patients

EduCan
Start date: November 27, 2017
Phase: N/A
Study type: Interventional

In addition to fatigue, pain is the most frequent and persistent symptom following breast cancer and breast cancer treatment. Despite the effectiveness of different physical therapy modalities, such as manual techniques, passive mobilizations and exercises, many patients still experience pain and subsequent difficulties in daily functioning at short and long term. Past decades, the awareness on the important role of educational interventions in the management of pain in general has increased. Educational interventions aim at explaining and improving the knowledge, control and attitude of the patient regarding his/her pain complaint. However, these educational interventions are often restricted to more biomedical pain management instructions and general advice on physical activity and analgesics (= traditional biomedical education). Only recently, increased knowledge on pain mechanisms led to a more modern educational approach. This modern approach is suited to explain more complex issues associated with pain and takes into account many more factors related to pain. To our knowledge, only one controlled trial investigated the effectiveness of a modern educational intervention in the early stage of breast cancer treatment. The results were very promising for shoulder function. However, only short-term effects were examined, no randomization was performed and no pain-related and socio-economic outcomes were evaluated. Therefore, the aim of the proposed project is to investigate the effectiveness of a similar modern educational program, in addition to standard physical therapy care, in the early treatment phase of breast cancer in comparison with traditional biomedical education. A randomized controlled trial will be performed with a long-term follow up period. The primary outcome parameter is pain-related disability. Secondary outcomes are different dimensions of pain, physical and mental functioning, return to work and health-care related costs.