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Pain clinical trials

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NCT ID: NCT03800901 Completed - Hypertension Clinical Trials

Quality IQ Patient Simulation Physician Practice Measurement and Engagement

Q-IQ
Start date: January 11, 2019
Phase: N/A
Study type: Interventional

This study will test the quality of physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and feedback. The study will also measure the impact of gaming-inspired competition and motivation, including a weekly leaderboard, to improve evidence-based care decisions. In addition, the study the test the impact of CME and MOC credits on participant engagement in the process.

NCT ID: NCT03797924 Completed - Pain Clinical Trials

Intercostobrachial Nerve Block (ICBN) for Tourniquet Pain: Is it Necessary?

ICBN
Start date: April 25, 2019
Phase: Early Phase 1
Study type: Interventional

In this study the investigators would like to show that when patients undergo upper limb surgery under supraclavicular brachial plexus block, additional blocking of the Intercostobrachial Nerve Block (ICBN) does not affect the incidence or course of tourniquet pain.

NCT ID: NCT03790098 Completed - Pain Clinical Trials

Flow-Restorative Yoga to Decrease Pain and Inflammation

Start date: November 19, 2018
Phase: N/A
Study type: Interventional

The Restorative Flow Yoga Study is a pilot project looking at whether restorative flow yoga will reduce inflammation and pain in women 60 and older who experience chronic pain.

NCT ID: NCT03787030 Completed - Pain Clinical Trials

Application of Vitamin E on Anal Fissure

Start date: December 21, 2018
Phase: Phase 3
Study type: Interventional

Patients were randomized into 2 groups: - Vitamin E: Vitamin E ointment will be applied during 8 weeks - Nitroglycerin: Nitroglycerin ointment will be applied during 8 weeks Healing rate of chronic anal fissure in patients receiving Nitroglycerin ointment and subjects patients receiving Vitamin E ointment were evaluated .

NCT ID: NCT03786055 Completed - Pain Clinical Trials

Somatic Yoga and Meditation for Cancer Survivors With Pain From Neuropathy

Y4CIPN
Start date: June 4, 2018
Phase: N/A
Study type: Interventional

Chemotherapy-induced peripheral neuropathy syndrome (CIPN) causes significant pain in hands and feet and is an adverse effect of treatment. Few non-pharmacological interventions have been tested and individuals experience CIPN symptoms years after treatment. This is the first study to explore a somatic yoga and meditation (SYM) intervention on functional outcomes and quality of life in cancer survivors.

NCT ID: NCT03785756 Completed - Pain Clinical Trials

Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars

Start date: April 29, 2019
Phase: Phase 3
Study type: Interventional

This is a single centre, randomised, double-blind, double-dummy, parallel group, multiple-dose, active and placebo-controlled efficacy study to evaluate the efficacy and safety of 2×300mg ibuprofen Prolonged Release (PR) tablets in subjects with postoperative dental pain.

NCT ID: NCT03785613 Completed - Pain Clinical Trials

Clinical Pilot Study in Healthy Men to Characterize the Uptake of Buprenorphine Into and Its Elimination From the Body After Topical Application of Two New Forms of a Skin Patch in Comparison to a Reference Patch

Start date: November 7, 2005
Phase: Phase 1
Study type: Interventional

This study is intended to produce information on the pharmacokinetic characteristics (uptake into and elimination from the body) of two new patch formulations of the analgesic buprenorphine as compared to the reference patch Transtec (Registered Trademark) 35 micrograms per hour (μg/h) in order to assess the suitability of the test formulations for a later confirmatory bioequivalence study. In addition to a reduced buprenorphine load, the new patch formulations may potentially provide improved wearing properties. A placebo patch formulation of the respective test or reference patch will be applied simultaneously to explore the skin tolerability and skin adhesiveness of the patch formulations. Furthermore, the safety and tolerability of the treatments will be assessed.

NCT ID: NCT03785353 Completed - Pain Clinical Trials

The Effects of Pain Neuroscience Education in a Spanish-Speaking Population

Start date: March 26, 2019
Phase: N/A
Study type: Interventional

Pain Neuroscience Education (PNE) has been shown to be effective to alter beliefs and decrease pain among individuals with musculoskeletal pain. Additionally, PNE has been shown to alter beliefs among middle school children. This study plans to assess the effects of PNE within a group of Spanish-speaking individuals.

NCT ID: NCT03784352 Completed - Pain Clinical Trials

Virtual Reality Pediatric Orthopaedic Outpatient Procedures

VPRO
Start date: February 5, 2019
Phase: N/A
Study type: Interventional

The main objective of the study is to evaluate the use of Virtual Reality (VR) in managing pain and anxiety levels during common pediatric orthopaedic outpatient procedures which include: cast application, cast removal, hardware removal (ie. pins and screws), and botox injections.

NCT ID: NCT03783702 Completed - Pain Clinical Trials

Pain Control Following Sinus Surgery

Start date: April 4, 2019
Phase: Phase 4
Study type: Interventional

Given the ongoing national opioid epidemic, an increased interest has developed in optimizing opioid prescribing practices of physicians, including otolaryngologists. Endoscopic sinus surgery (ESS) is one of the most commonly performed surgeries by otolaryngologists with over 250,000 ESS's performed annually in the U.S. Multiple studies have shown that, compared to the amount patients actually consume, otolaryngologists prescribe a high quantity of opioids to patients recovering from ESS). It has been shown that these excess opioid medications contribute to prolonged use or abuse by the patient, family members, or friends. The purpose of this study is to better understand the pain management requirements of patients who undergo ESS for recurrent acute rhinosinusitis (RARS) or chronic rhinosinusitis (CRS). This prospective, randomized, multi-institutional controlled trial will aim to determine the degree to which pain following ESS can be adequately controlled by non-opioid medications. It will also determine whether post-ESS narcotic use can be avoided entirely, or at least significantly limited. Patients will be randomized into two groups, each of which will receive a stepwise analgesic regimen consisting of acetaminophen and oxycodone or acetaminophen and ibuprofen. Pain will be assessed daily using visual analog scales (VAS) and the Brief Pain Inventory (BPI). The results of this study will help to develop a standardized approach to pain management in the post-ESS setting and help to elucidate the role of non-opioid pain medications. The ultimate goal would be to positively affect opioid prescribing patterns among surgeons who perform ESS in order to significantly reduce the quantity of opioids prescribed to patients while continuing to adequately manage patients' pain.