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Pain clinical trials

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NCT ID: NCT05322018 Recruiting - Pain Clinical Trials

Validation of Faces Thermometer Scale (FTS)

Start date: May 1, 2022
Phase:
Study type: Observational

The aim of this study is to evaluate validity and reliability of a novel digital pain measure tool, the Faces Thermometer Scale (FTS). Pain is commonly reported by children and adolescents undergoing dental treatment. Pain is also a strongly contributing factor in the development of Dental Fear and Anxiety (DFA). Professionals often underestimate the pain perceived by their patients. Self-report tools are seldom used to measure pain in a clinical setting, denying child patients the possibility to communicate their pain experiences. The aim of this study is to evaluate validity and reliability of a digital self-report pain measure tool, the Faces Thermometer Scale (FTS). Children and adolescents (N=150) aged 8 to 17 years visiting a dental clinic will be asked to score their pain using three different self-report pain tools; FTS, Faces Pain Scale-Revised (FPS-R) and Color Analog Scale (CAS). The validity and reliability of FPS-R and CAS is long established and will therefore be used to evaluate the psychometric properties of FTS.

NCT ID: NCT05320432 Completed - Pain Clinical Trials

Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion

TENS 2 0
Start date: January 20, 2023
Phase: N/A
Study type: Interventional

First-trimester abortion aspiration procedures are painful and sedation is typically provided. It is unsafe to drive after sedation due to the prolonged motor delay from some anesthetic agents. Without a known escort, most clinics do not allow patients to use public transportation, taxis, or rideshare services. Arranging a ride may be harder for those seeking abortion care than other surgical procedures given privacy concerns and the need to travel far distances. Additionally, some people have medical reasons that makes sedation in an outpatient abortion clinic unsafe. As abortion restrictions increase and more people need to travel far distances to access care, it is important to investigate non-pharmacologic pain control options. Transcutaneous electrical nerve stimulation (TENS) delivers a low-level electrical current through the skin. By activating the descending inhibitory systems in the central nervous system, these pulses of electrical current reduce sensitivity to pain. TENS has been shown to be effective in decreasing pain with menstrual cramps and during medication abortion, and it was found to be non-inferior to IV sedation for first-trimester procedural abortion. However, it remains unclear if TENS is better than ibuprofen and local anesthesia via paracervical block alone. The overarching goal of this research is to identify an inexpensive, non-pharmacologic, alternative pain control strategy for those with a medical or social contraindication to IV sedation. The specific aim of this project is to evaluate the efficacy of TENS to prevent pain during first-trimester procedural abortion. To achieve this objective, a blinded, randomized superiority trial comparing the use of TENS to sham for management of pain during first-trimester aspiration abortion is proposed. This research is significant because the validation of a non-pharmacologic pain management technique would decrease barriers to accessing abortion care.

NCT ID: NCT05318846 Completed - Pain Clinical Trials

A Study to Evaluate the Efficacy and Safety of HRS4800 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.

Start date: January 14, 2022
Phase: Phase 2
Study type: Interventional

The study is being conducted to evaluate the efficacy and safety of HRS4800 tablets for postoperative analgesia after impacted teeth removal surgery.

NCT ID: NCT05317312 Completed - Pain Clinical Trials

Study of MR-107A-02 in the Treatment of Post Surgical Dental Pain.

Start date: March 31, 2022
Phase: Phase 2
Study type: Interventional

MR-107A-02 is being studied to investigate its efficacy, safety and dose-response after dental surgery.

NCT ID: NCT05317026 Recruiting - Pain Clinical Trials

Increased Early Pain Relief by Adding Vertebroplasty to SBRT

Start date: April 3, 2023
Phase: N/A
Study type: Interventional

The goal of treating metastases is to preserve stability and neurological function while reducing pain. The actual standard of care is stereotaxic body radiation therapy (SBRT) alone in non-surgical patients. The added value of vertebroplasty to SBRT is not well documented in the literature, nor whether performing vertebroplasty before radiotherapy treatment leads to a reduction in the rate of fractures and post-SBRT pain.

NCT ID: NCT05315999 Recruiting - Pain Clinical Trials

Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care

ProTreat
Start date: May 3, 2022
Phase: Phase 2
Study type: Interventional

Palliative cancer patients with tumor pain often suffer from nausea and vomiting when starting pain therapy with opioids. The objective of the clinical pilot trial is to evaluate the efficacy and tolerability of palonosetron in the prophylactic treatment of opioid-induced nausea and vomiting.

NCT ID: NCT05313789 Not yet recruiting - Pain Clinical Trials

Analgesia Nociception Index for Pain Monitoring in Intensive Care Units

Start date: April 11, 2022
Phase:
Study type: Observational

The aim of this study is to examine the usability of ANI in patients who will be treated in intensive care unit.

NCT ID: NCT05312515 Completed - Pain Clinical Trials

The Effect of Hot Bag/Warm Application on Feet After Cesarean Delivery on Postpartum Comfort, Pain and Flatus

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The postpartum period is a process in which both physical (bleeding, infection, anemia) and emotional (delay in breastfeeding and mother-baby relationship) problems occur in women. Among the conditions that physically affect the woman who has had a cesarean section, a decrease in bowel movements is often seen and this decrease can last for 24 hours or longer. Initiation of bowel movements after surgery, time of first flatulence and defecation are important factors that determine postoperative patient comfort.

NCT ID: NCT05312502 Completed - Pain Clinical Trials

Effect of Using a Birth Ball on Birth Satisfaction and Pain in Pregnant Women During Labor

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

H0: There is no difference between birth satisfaction and pain levels of pregnant women who used and did not use a birth ball during labor. H1: There is a difference between birth satisfaction and pain levels of pregnant women who used and did not use a birth ball during the birth process.

NCT ID: NCT05311995 Completed - Pain Clinical Trials

Which Trocar Access Site Should We Use in Laparoscopic Appendectomy?

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Open appendectomy has been used in the treatment of appendicitis, which is among the most common emergency pathologies worldwide, since the end of the 19th century. In the 20th century, laparoscopic appendectomy came to the fore and the frequency of use increased gradually. Despite the frequency of laparoscopic appendectomy, there is no consensus on the best way to perform each procedural step. One of these steps is the trocar entry areas. In this study, investigator's aim is to compare the trocar entry areas, which are various reports in the literature, and to find the localization with the optimal usage area. 140 patients who underwent laparoscopic appendectomy between 2021-2022 were randomized into four groups and included in the study. Demographic data, peroperative findings, complications, length of stay and post-operative VAS values of the patients were evaluated.