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Pain clinical trials

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NCT ID: NCT05338983 Not yet recruiting - Pain Clinical Trials

Effect of Different Approaches of Delivering Local Dental Anesthesia on Pain Perception in Children.

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare the efficacy of three different approaches of local anesthesia (LA) administration (Warm[37°C] LA, Buffered LA, and BUZZY device) on pain perception to young children ( 6-12 years old) using sound -eye -motor and Wong-Baker FPR scales.

NCT ID: NCT05337709 Recruiting - Pain Clinical Trials

Pharmacist Provided Intervention (Education and Medication Review) in Osteoarthritis

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to initiate pharmacist intervention (educational and medication review) among osteoarthritis patients visiting community pharmacies.

NCT ID: NCT05335668 Recruiting - Pain Clinical Trials

Brain Circuitry Changes in Central Poststroke Pain: a Clinical and Neuroimaging Study

Start date: July 18, 2022
Phase: N/A
Study type: Interventional

Central poststroke pain (CPP) is estimated to affect up to 10% of stroke patients and is one of the most difficult-to-treat conditions with a detrimental effect on patient's quality of life. So far, no drug has proven efficient to alleviate CPP and neuromodulation approaches including Deep Brain Stimulation (DBS) and motor-cortex stimulation have yielded mixed results with only a few patients experiencing long-term pain relief. To date, little is known about the pathophysiology of CPP. There is at present little evidence for a clear association between the specific location of lesions, clinical manifestation and phenomenology of pain as well as treatment response of CPP patients. Furthermore, the time delay between stroke occurrence and CPP occurrence is highly variable and the fact, that it is not immediate in the great majority of patients suggests that other factors contribute to the development of CPP. These factors have not been identified yet.

NCT ID: NCT05332119 Completed - Pain Clinical Trials

Virtual Reality During the Removal of Chest Drains in Critically-ill Patients

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Appropriate pain and anxiety management of critically-ill patients during bedside procedures remains a big challenge. Clinical Practice Guidelines recommend preemptive analgesia or non-pharmacological interventions, such as relaxation techniques or distraction, to prevent and treat pain during nursing procedures. One of the most painful procedures in the Intensive Care Unit (ICU) is the removal of chest drains in post-cardiac surgical patients. Virtual reality (VR) is a computer-generated simulation of a 360º immersive world in which the patient can receive visual and auditory stimuli that distract them from the real environment. Current research has demonstrated that VR reduced pain and anxiety in intravenous catheter insertions or wound care. The primary objective of the study is to evaluate the effectiveness of VR on pain and anxiety during the removal of chest drains, in post-cardiac surgical patients. The hypothesis is that VR reduces both pain and anxiety, in critically-ill patients, during the removal of chest drains in post-cardiac surgical patients.

NCT ID: NCT05329467 Recruiting - Pain Clinical Trials

Validation of Pain Assessment Scale Faces Thermometer Scale (FTS)

Start date: September 17, 2021
Phase: N/A
Study type: Interventional

The aim of the study was to psychometrically evaluate the electronic self assessment Faces Pain Scale (FPS). Validation is performed in relation to golden standard of pain scale assessments Faces Pain Scale Reversed (FPS-R) and Coloured analogue Scale (CAS). 600 children with a range of illnesses on various paediatric healthcare settings in Sweden, Island, Denmark and USA will be included. Pain assessment will take place postoperatively, in relation to procedures or in a setting where acute pain is identified.

NCT ID: NCT05327777 Completed - Pain Clinical Trials

Toward Zero Prescribed Opioids for Outpatient General Surgery

Start date: November 1, 2019
Phase: Phase 4
Study type: Interventional

Investigators have created an opioid reduction "package" which includes patient education, non-narcotic pain control instructions, and limited (or no) opioid pain prescriptions provided at discharge in an attempt to reduce the number of opioid consumption after outpatient general surgery.

NCT ID: NCT05326737 Recruiting - Pain Clinical Trials

Evaluation of Pain Trajectories After Surgery and Their Potential Relationship With Chronicity at 3 Months

ETADOL
Start date: February 23, 2021
Phase:
Study type: Observational

The effective management of acute postoperative pain remains a daily challenge despite the organizational efforts made and the techniques put in place. Thirty percent of patients who undergo surgery suffer from chronic post-surgical pain, of which 5 to 10% are of severe intensity. Many preoperative, intraoperative, and postoperative factors, related to the patient, the surgical procedure, or the anesthetic technique, have been incriminated as risk factors for chronic post-surgical pain. The severity of acute postoperative pain is recognized as one of the risk factors for the occurrence of chronic post-surgical pain on which we can hope to interact during the peri-operative period. In this cohort study, we wish to define the typologies of postoperative pain trajectories observed from Day 0 to Day 7 and to estimate the proportion of patients with an abnormal resolution of pain in a model of organization such as that of our institution, in classic hospitalization and in ambulatory care.

NCT ID: NCT05326711 Completed - Pain Clinical Trials

Effects of Telerehabilitation-Based Motor Imagery Training on Pain in People With Multiple Sclerosis

Start date: April 11, 2022
Phase: N/A
Study type: Interventional

In this studly, the effects of an 8-week telerehabilitation-based motor imagery training on pain and related factors in persons with multiple sclerosis will be investigated.

NCT ID: NCT05323383 Recruiting - Pain Clinical Trials

The Effects and Mechanisms of Brief Mindfulness Meditation and Hypnosis for Pain

Start date: March 24, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effects and mechanisms of 1 x 20-min training in mindfulness meditation and self-hypnosis relative to an inert control. Participants will be randomly assigned to condition. The dual primary outcomes will be pre- to post-training changes in current pain intensity and pain unpleasantness. The active treatments are hypothesized to produce greater reductions in pain outcomes than the control. It is also hypothesized that change in mindfulness will be a mediator specific to mindfulness meditation, while change in affect and decentering will be mediators of the hypnosis condition. Moderators of response will also be explored.

NCT ID: NCT05323071 Completed - Pain Clinical Trials

Comparison of the Efficacy of Oral Sucrose Administration at Two Different Times of a Painful Procedure in Neonates.

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to compare the use of 24% sucrose in pain control in neonates from 32 weeks of gestation onwards according to the time of administration of sucrose in venous and arterial puncture for blood collection.