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Pain, Postoperative clinical trials

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NCT ID: NCT03989570 Completed - Postoperative Pain Clinical Trials

Transversus Abdominis Plane Block Versus Erector Spinae Plane Block

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

The TAP block, first described by Rafi in 2001, is comprised of deposition of a local anesthetic into the anatomical plane between the internal oblique and transverses abdominis muscles, where thess thoracoabdominal nerves (T6-L1) contribute to the main sensory supply of the skin, muscles, and parietal peritoneum of the anterior abdominal wall. These nerves branch and communicate extensively with each other in the TAP . Erector spinae plane (ESP) block is a recently described interfascial block in which the local anaesthectic is placed over or below the plane of the erector spinae muscle, near where the spinal nerves come out from the spine before they start to divide. Some publications have shown its effectiveness in treating thoracic and abdominal postoperative pain. Postoperative pain is the major obstacle for early postoperative ambulation and increases the risk of venous thromboembolism, respiratory complications and prolongs the hospital stay. Parietal pain is the chief component of postoperative pain after abdominal surgeries. Large doses of opioids are required to mitigate this pain, but they are poorly tolerated. Multimodal analgesia is effective in handling postoperative pain and in attenuating the side effects of large doses of a single analgesic .

NCT ID: NCT03988127 Completed - Pain, Postoperative Clinical Trials

Perfusion Index in Pain Assessment

Start date: July 20, 2019
Phase:
Study type: Observational

The perfusion index (PI) is the ratio of the pulsatile to the non-pulsatile blood flow in peripheral tissue. It represents a non-invasive measure of peripheral perfusion that can be continuously obtained from a pulse oximeter. This property explains the fact that it decreases with vasoconstriction and increases with vasodilatation. An increase in PI was proved to be an early indicator for the success of general and regional anaesthesia, which cause initial peripheral vasodilatation before the onset of anaesthetic effect. Whereas a failed increase in PI would suggest failure of anaesthesia. The PI has been reported to decrease when noxious stimulus was applied to anaesthetized volunteers. A recent study on critically ill non-intubated patients has demonstrated a good correlation between changes in PI and changes in Behavioral Pain Scale-non intubated values after a painful stimulus was applied. Despite the rising use of perfusion index in anaesthesia and intensive care, few studies have investigated its capability as a pain assessment tool, and to our knowledge, it has not been investigated in intubated critically ill patients yet.

NCT ID: NCT03982784 Completed - Pain Management Clinical Trials

TQLB for Postoperative Pain After Laparoscopic Partial Nephrectomy

Start date: June 10, 2019
Phase: N/A
Study type: Interventional

This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic partial nephrectomy.

NCT ID: NCT03981237 Completed - Post-operative Pain Clinical Trials

Postoperative Pain After Ultrasonically and Laser-activated Irrigation During Root Canal Treatment

Start date: March 25, 2019
Phase: N/A
Study type: Interventional

The aim of this prospective, randomized clinical study is to compare the frequency and intensity of post-operative pain after root canal treatment with ultrasonically-activated or laser-activated irrigation.

NCT ID: NCT03979469 Completed - Clinical trials for Effect of Anesthesia in Discharge Time From the Hospital

Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children

Start date: August 1, 2018
Phase: Phase 2
Study type: Interventional

The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and discharge times. Quality of postanesthetic care was estimated in a 24h follow up.

NCT ID: NCT03979105 Completed - Pain Clinical Trials

Cardiovascular Safety After Continuous Ketamine Infusion

Start date: July 1, 2017
Phase:
Study type: Observational

Observational study that evaluate the cardiovascular and neuropsychiatric side effects of ketamine analgesic infusions for acute pain

NCT ID: NCT03978923 Completed - Clinical trials for Preparation of the Implant Site With Piezosurgery vs Drill

Observational Study on the Preparation of the Implant Site With Piezosurgery vs Drill: Comparison Between the Two Methods in Terms of Post-operative Pain, Surgical Times and Operational Advantages

Start date: January 1, 2013
Phase:
Study type: Observational

Purpose: Recent advances showed that ultrasonic implant site osteotomy is related with a decreased trauma and a better post operative healing of the surgical site if compared to the traditional drilling techniques. The micrometric bone cutting control and the operative advantages related to the piezoelectric approach is also characterized by a learning curve for the clinician in surgical practice and an increased operative duration of the procedure. The aim of this investigation was to compare the operative time, the post operative pain and the patients frequency of intake of painkillers in the healing period. Methods: A total of 75 patients were treated at the Unit of Oral Surgery (Department of Medical Sciences, Surgery and Health, University of Trieste, Italy) in a split mouth model: 75 drill-inserted implants (G1) and 75 piezoelectric device- inserted implants (G2). The Visual Analogue Scale (VAS) was performed to evaluate the post-operative pain at 15 days from the surgery. The operative time and frequency of intake of painkillers was measured.

NCT ID: NCT03972397 Completed - Pain, Postoperative Clinical Trials

Intercostal Nerve Cryoablation for Postoperative Pain Management

Start date: July 15, 2019
Phase: Phase 4
Study type: Interventional

The purpose of the study is to assess the efficacy of intercostal nerve cryoablation on the magnitude and duration of postoperative pain control both in patients undergoing thoracoabdominal incisions for the descending or thoracoabdominal aortic aneurysm repair.

NCT ID: NCT03969316 Completed - Pain, Postoperative Clinical Trials

Transversus Abdominis Plane Block Versus Quadratus Lumborum Block in The Pediatric Population Undergoing Orchiopexy

Start date: May 10, 2019
Phase: N/A
Study type: Interventional

Transversus abdominis plane (TAP) and Quadratus lumborum (QL) blocks are used for the management of acute pain treatment, especially after the lower and upper abdominal surgeries. The TAP block which is one of the abdominal truncal blocks is performed with the blockage of the nerve group which innervates the anterior abdominal muscle wall layers. However, in QL block, the local anesthetic agent spreads through the abdominal wall and paravertebral space with the help of the perimuscular fascia to maintain the somatic analgesia. The investigators' aim in this study, to investigate the effect of the TAP and QL blocks on peroperative and postoperative analgesic consumption in children undergoing unilateral elective orchiopexy.

NCT ID: NCT03969277 Completed - Pain, Postoperative Clinical Trials

Graded Motor Imagery in Elbow Limitation

Start date: October 15, 2019
Phase: N/A
Study type: Interventional

This randomized-controlled trial aims to investigate the efficacy of Graded Motor Imagery (GMI) on function, pain, and range of motion (ROM) in patients with a posttraumatic stiff elbow.