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Post-operative Pain clinical trials

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NCT ID: NCT03513237 Not yet recruiting - Post Operative Pain Clinical Trials

Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain

Start date: May 15, 2018
Phase: N/A
Study type: Interventional

Caesarean section is a common method of delivery in obstetrics. With the recent increase in the rate of this procedure, it is wise to understand and implement the optimal surgical technique. Therefore, different operational methods have been defined to reduce the risk of peri/post-operative morbidity. The digital dilatation of cervix during elective caesarean section has still been a concern when evaluating this issue. This procedure is supposed to help the drainage of blood and lochia postpartum, thus reducing infection or the risk of postpartum haemorrhage (PPH). However, on the contrary, this mechanical manipulation may also result in contamination by a vaginal micro-organism and increase the risk of infections or cervical trauma. Additionally, the effect of routine cervical dilatation on patients' perception of pain has not been studied sufficiently yet. As a result, the current literature lacks evidence of cervical dilatation on postoperative pain and is even not all in agreement regarding the potential benefits on overall maternal morbidity.

NCT ID: NCT03484650 Not yet recruiting - Post Operative Pain Clinical Trials

Systemic Lidocaine Infusion for Pain Control in Ventral Hernia

Start date: June 1, 2018
Phase: Phase 3
Study type: Interventional

Ventral hernia repair leads to more than expected pain. This is thought to be secondary to nerve pain at the lateral transfixion sutures. Systemic lidocaine given pre-op has in other situations decreased neurogenic pain. This study will examine its effects on pain experienced after ventral hernia repair.

NCT ID: NCT03476772 Not yet recruiting - Post Operative Pain Clinical Trials

Nalbuphine Plus Caudal Bupivacaine in Hypospadius Repair

Start date: March 2018
Phase:
Study type: Observational

Caudal aneasthesia for pediatric surgery was first reported in 1933. Since then, studies have described the indications for pediatric caudal block, the level of analgesia, doses, advantages and disadvantages of this technique. In children, caudal anesthesia is most effectively used as adjunct to general aneasthesia and has an opioid-sparing effect, permitting faster and smoother emergence from aneasthesia. A single shot caudal anesthesia provides relatively brief analgesia for 4 to 8 hours depending on the agent used. Prolongation of anesthesia can be achieved by adding various adjuvants, such as opioids and nonopioids such as clonidine, ketamine, midazolam, and neostigmine,with varying degrees of success.

NCT ID: NCT03448263 Completed - Post Operative Pain Clinical Trials

Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.

PEP
Start date: January 4, 2018
Phase: N/A
Study type: Interventional

The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using Balanced Force technique and two reciprocating system when cryotherapy is used. Methodology: All 216 patients had upper or lower molar, premolar or anterior teeth selected for conventional RCT for prosthetic reasons detected with only vital pulps. Of the sample of 216 teeth, were selected to the 3 instrumentation methods. For hand instrumentation, Balanced Force were used. All canals were clean and shaped with hand Flex-R files (fMoyco/Union Broach, York PA, USA). For mechanical shaping, all instruments were used with a micro motor (VDW, Munich Germany). WaveOne and Reciproc instruments. Final irrigation with cold (6oC) 17% EDTA served as a lubricant.

NCT ID: NCT03391284 Enrolling by invitation - Post-operative Pain Clinical Trials

Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery

Start date: February 2016
Phase: N/A
Study type: Interventional

Hypothesis: Postoperative pain will be equivalent in patients receiving preemptive oral acetaminophen as compared to patients receiving preemptive intravenous acetaminophen following minimally invasive benign gynecologic surgery. Primary outcome: • Difference in postoperative pain comparing preemptive use of PO versus IV acetaminophen o Mean Visual analog Scale (VAS) scores will be compared between the intervention group (PO acetaminophen) and the control group (IV acetaminophen). Secondary outcomes: - Difference in postoperative analgesic use between groups o Narcotics, NSAIDs - Difference in postoperative N/V between groups o Patient rated measure - none, mild, moderate, severe - Cost comparison between drugs

NCT ID: NCT03359798 Not yet recruiting - Cesarean Section Clinical Trials

RCT of Counseling Intervention on Post-op Opiate Use

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial to investigate the effect of a simple counseling intervention on post-operative narcotic requirements, with the hypothesis that women receiving this intervention will use fewer narcotics for pain management following cesarean section.

NCT ID: NCT03347266 Recruiting - Post-Operative Pain Clinical Trials

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.

Start date: November 2017
Phase: Phase 2
Study type: Interventional

The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.

NCT ID: NCT03304444 Recruiting - Post Operative Pain Clinical Trials

A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery

Start date: August 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the comparison between liposomal bupivacaine versus bupivacaine HCl in Transversus Abdominis Plane blocks for gynecologic surgery on the length of stay in the hospital, total narcotic use, and overall complications rates.

NCT ID: NCT03277391 Recruiting - Post-operative Pain Clinical Trials

Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery

Serrathos
Start date: April 14, 2017
Phase: N/A
Study type: Interventional

The objective of the study is to compare the efficacy of the Serratus Anterior Plane block (SPB) realised in its deep plane, with a multi-holed catheter in place for twenty four hours, to a standard intravenous analgesia for small videoassisted thoracic surgery interventions. The objective is also to evaluate the resorption rate of local anesthetic at this level, and make a population pharmacokinetic analysis.

NCT ID: NCT03254056 Recruiting - Post-operative Pain Clinical Trials

Fascial Closure Techniques Post-Operative Pain Laparoscopy

Start date: October 3, 2017
Phase: N/A
Study type: Interventional

This study compares post-operative incisional pain on post-operative days 1 and 7 who will undergo gynecologic laparoscopic operations. Half of participants will undergo conventional fascial closure, while the other will undergo fascial closure by Berci Fascial Closure (Karl Storz, Belgium).