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Pain, Postoperative clinical trials

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NCT ID: NCT05752305 Completed - Pain, Postoperative Clinical Trials

Use of Corticosteroids in Third Molar Surgery

Start date: January 15, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Surgical extraction of retained lower third molars is associated with the development of postoperative complications, including inflammation, trismus and postoperative pain, that lead to a decrease in patients' quality of life. Therefore, the use of drugs is essential to reduce the morbidity associated with surgery, with NSAIDs and corticosteroids being the most commonly used drugs.

NCT ID: NCT05751421 Enrolling by invitation - Pain, Postoperative Clinical Trials

Pain Relief After PrimaryTKA

Start date: February 28, 2023
Phase: Phase 3
Study type: Interventional

While a majority of people who undergo TKA have significant long-term improvement in functional ability, many patients may experience significant pain in the early postoperative period, which may adversely impact postoperative rehabilitation and recovery. Traditionally, opioid medications have been used to control postoperative pain. However, there are many risks with using opioid medications, including addiction and overdose, which kills over 48,000 people yearly. In an effort to overcome this, opioid-sparing multimodal analgesia (MMA) regimens have been developed, commonly using nonsteroid anti-inflammatory drugs (NSAIDs), acetaminophen, regional nerve blocks, and local anesthesia.

NCT ID: NCT05746143 Recruiting - Pain, Postoperative Clinical Trials

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.

NCT ID: NCT05744544 Completed - Pain Clinical Trials

Sensory Assessment and Regression Rate of Bilateral External Oblique Intercostal Block and m-TAPA Block

Start date: May 2, 2023
Phase:
Study type: Observational [Patient Registry]

External oblique and m-tapa blocks are routinely performed on patients undergoing laparoscopic cholecystectomy in our clinic. In this study, sensory block and regression rates will be investigated in patients who underwent block.

NCT ID: NCT05743231 Recruiting - Postoperative Pain Clinical Trials

Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery

Start date: November 29, 2022
Phase: N/A
Study type: Interventional

Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a severely painful postoperative period is experienced as the intercostal nerves are cut. Invasive cardiac surgery is necessary surgery that can take steps to improve the quality of life and functional status of patients without sternotomy. However, patients may experience intense pain in the immediate postoperative period, which can lead to inactivity, increased risk of complications, and greater consumption of opioids, resulting in adverse effects and prolonged hospital stays. Pain management is challenging due to a large number of dermatomes covered. Interpectoral plane block + serratus anterior plane block, defined in 2012, has been used in many studies before as part of multimodal analgesia in minimally invasive cardiac surgery. Erector spinae block was also described in 2018 with positive results, which has been used in both sternotomies (open heart surgery) and minimally invasive procedures. Minimally invasive cardiac surgery can be excruciating in the postoperative period, just like thoracotomy surgeries. What is aimed in this study is to compare two previously known regional anesthesia techniques in this study.

NCT ID: NCT05739747 Recruiting - Chronic Pain Clinical Trials

Validation of the Gendolcat Score for the Prognosis of Chronic Postoperative Pain in Cesarean Section

Start date: April 1, 2023
Phase:
Study type: Observational [Patient Registry]

Chronic post-surgical pain is a problem that has historically been underestimated. Over the last few years there has been a search for strategies to both predict and prevent its occurrence in patients undergoing surgery. The Gendolcat index is the only predictive model that uses only objective pre-surgical variables to assess the risk of suffering chronic post-surgical pain. However, it is only validated for the following surgeries: thoracotomy, hysterectomy and open inguinal hernia. Our aim is to test whether the Gendolcat model is also valid for cesarean section.

NCT ID: NCT05738902 Recruiting - Ovarian Cancer Clinical Trials

Adherence and Compliance to ERAS in Gynecological Surgery

ERASGYNBS002
Start date: May 30, 2023
Phase:
Study type: Observational

The aim of the study is to investigate the association between early non-compliance to ERAS in postoperative day 2 (POD2) with the rate of postoperative complications.

NCT ID: NCT05737394 Recruiting - Postoperative Pain Clinical Trials

Lap-guided vs Us-guided TAP Block in Pediatric Laparoscopy

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Transversus Abdominis Plane (TAP) block is commonly used to control pain in laparoscopic procedures. It is usually administered with ultrasound guide but it can be also administered with laparoscopic assistance under direct visualization. Aim of the present study is determining if the lap-assisted TAP is superior to the us-guided TAP Block in pain control in the immediate postoperative phase as well at 1 and 6 hours post surgery.

NCT ID: NCT05729893 Recruiting - Post Operative Pain Clinical Trials

Evaluation of Post Operative Pain After Using Two Different Types of Sealers

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

conventional endodontic treatment is done using two different types of sealers in the obturation to evaluate the post operative pain between the two sealers

NCT ID: NCT05729308 Not yet recruiting - Clinical trials for Postoperative Pain, Acute

Comparative Study Between Caudal Epidural Block and Bilateral Erector Spinae Plane Block in Lumbosacral Spine Surgeries.

Start date: February 2023
Phase: N/A
Study type: Interventional

It is widely believed that major lumbosacral spine surgeries are associated with severe postoperative pain that may delay the functional recovery of the patient. Caudal epidural injection (CE) has an important role in providing effective pain relief post lumbosacral spine surgeries by blocking sensory input at the level of the spinal cord. Erector Spinae Plane Block (ESPB) is a relatively new technique of trunk fascial block which was introduced in 2016. Reports showed that ESPB significantly relieved postoperative pain in patients with lumbosacral spine surgery, reducing the use of analgesics.The overall benefit of intravenous (IV) analgesia versus pre-emptive analgesia by caudal epidural or erector spinae block is still controversial. The aim of this study is to compare the pre-emptive analgesic effect of bilateral erector spinae plane block versus Caudal epidural analgesia versus the conventional intravenous analgesia in adult patients undergoing lumbosacral spine surgeries under general anesthesia.