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Pain, Postoperative clinical trials

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NCT ID: NCT02001948 Completed - Postoperative Pain Clinical Trials

Intrathecal Morphine for Inguinal Hernia Repair.

Start date: July 2009
Phase: Phase 4
Study type: Interventional

The aim of this study was to compare the effects of two different doses of intrathecal morphine (0.1 mg and 0.4 mg) combined with 7.5 mg of heavy bupivacaine on postoperative block regression times, postoperative analgesia and the severity of side effects, for inguinal hernia repairs.

NCT ID: NCT02001259 Completed - Postoperative Pain Clinical Trials

Efficacy of Epidural Steroid for Controlling Pain After Primary TKA

Start date: January 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine efficacy of epidural steroid for postoperative pain control after TKA

NCT ID: NCT01995045 Completed - Retinal Detachment Clinical Trials

Postoperative Pain Control Following Vitreoretinal Surgery

Start date: July 2012
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate if patients receiving a steroid (triamcinolone acetonide) combined with local anesthesia and antibiotic following retina surgery have better postoperative pain control those receiving local anesthesia and antibiotic alone.

NCT ID: NCT01991288 Completed - Post Operative Pain Clinical Trials

Analgesic Efficacy of Saphenous Nerve Block in Total Knee Replacement

Start date: November 2012
Phase: Phase 4
Study type: Interventional

We hypothesize that preoperative saphenous nerve block (SNB) in combination with periarticular local infiltration provides better post operative pain relief (POPR) profile as compared to local infiltration alone

NCT ID: NCT01989117 Completed - Clinical trials for Osteoarthritis of the Knee

Effectiveness of Osteopathy in the Preoperative Treatment of Postoperative Pain in Patients Undergoing Total Knee Replacement

Start date: November 2013
Phase: N/A
Study type: Observational

Osteopathy is an alternative healthcare that seems effective in relieving the pain of patients. The main purpose of this study is to evaluate the efficacy of preoperative osteopathic care in patients undergoing total knee arthroplasty (TKA) for osteoarthritis. The secondary objectives are to assess pain during the first postoperative month on a VAS and knee function and quality of life at 6 months and 1 year. Our hypothesis is that osteopathy will decrease postoperative pain and increase knee function.

NCT ID: NCT01988194 Completed - Depression Clinical Trials

Pragmatic Research eXamining Inpatient Symptoms

PRAXIS
Start date: November 2013
Phase: N/A
Study type: Interventional

Many hospitalized patients experience pain during their hospital stay, and less than half report adequate pain relief. Common treatments for pain include opioid medications, which have associated side effects and complications. Research has shown that acupuncture is effective for surgical, postoperative and cancer-related pain, nausea, and vomiting. More research is needed on the effectiveness of adding acupuncture to routine care for hospitalized patients. The objective of this study is to examine the effectiveness of acupuncture delivered in a "real-world" setting according to the principles of traditional Chinese medicine among hospitalized patients to manage pain and other symptoms. 250 hospitalized participants will be randomized in a 1 to 1 ratio to receive either 1) usual care or 2) usual care with acupuncture offered (125 in each group). The primary outcome measure will be change in daily pain intensity. Data on other symptoms, such as nausea, vomiting, anxiety, and depression, as well as functionality and quality of life will be collected in person, on a web-based survey, or via telephone follow-up. The aims of the study are to examine the effectiveness of acupuncture to manage pain and other symptoms among hospitalized patients; to evaluate the impact of acupuncture on patient satisfaction among hospitalized patients; and to estimate costs and cost-effectiveness of acupuncture among a subset of hospitalized patients. The investigators hypothesize that compared to hospitalized patients receiving usual care alone, hospitalized patients receiving acupuncture will have: 1. decreased pain severity 2. higher patient satisfaction

NCT ID: NCT01984463 Terminated - Postoperative Pain Clinical Trials

Impact of Epidural Morphine on Shoulder Pain Following Thoracotomy.

Start date: February 2014
Phase: N/A
Study type: Interventional

This study is designed to assess the impact of epidural morphine on: - The incidence and severity of shoulder pain following a thoracotomy. - The need for additional analgesics, such as opioids for the relief of shoulder pain. - Its safety profile compared to epidural fentanyl following a thoracotomy. The basic hypothesis of this study is that an infusion of epidural bupivacaine and morphine initiated after the induction of anesthesia and continued until 72 hours postoperatively will reduce the incidence and severity of shoulder pain following a thoracotomy when compared to an epidural infusion of bupivacaine and fentanyl.

NCT ID: NCT01983111 Completed - Pain Clinical Trials

Compare the Efficacy and Safety of Norspan to Tramadol/Acetaminophen With Prolonged Postoperative Pain (PASSION)

Start date: October 2013
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of buprenorphine transdermal system to tramadol/acetaminophen.

NCT ID: NCT01983020 Completed - Postoperative Pain Clinical Trials

Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery

Start date: April 2011
Phase: Phase 3
Study type: Interventional

This study has been designed as a controlled clinical trial to evaluate the efficacy of brief lidocaine infusion, brief ketamine infusion and a lidocaine/ketamine combined infusion when added to conventional opioid therapy following major spine surgery, as well as to evaluate the effects of the lidocaine/ketamine pain protocol on the feasibility of performing routine intraoperative neurophysiology during spine surgery in adults and determine whether this infusion protocol is compatible with intraoperative neurophysiology on spine surgery patients. If one or more of the approaches is confirmed as efficacious and safe, it could have a significant impact on the routine management of postoperative pain in this context.

NCT ID: NCT01981369 Completed - Postoperative Pain Clinical Trials

Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular Block

Start date: January 2014
Phase: N/A
Study type: Interventional

The study will evaluate the effect of Dexmedetomidine sedation on the duration of infraclavicular block in patients scheduled for surgery of elbow, forearm and/or hand. All patients will receive infraclavicular block before the surgery and then they will be randomized to receive either Dexmedetomidine or Propofol sedation. Duration of the sensory block will be evaluated in recovery room, 24 and 48 hours after the surgery. Hypothesis: Primary: Dexmedetomidine sedation increases the duration of sensory infraclavicular block in patients scheduled for upper limb surgery. Secondary: Dexmedetomidine sedation - Gives an adequate level of sedation during the surgical procedure - Reduces the requirements of postoperative opioids - Improves the quality of sleep on the night of the surgery - Increases patients satisfaction regarding the anesthesia technique - Dexmedetomidine sedation is safe and easy to use - Dexmedetomidine sedation provides less respiratory depression during the procedure.