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Pain, Postoperative clinical trials

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NCT ID: NCT02276911 Terminated - Clinical trials for Cervical Spondylosis

Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery

Start date: March 1, 2015
Phase: Phase 2
Study type: Interventional

A prospective, randomized, placebo controlled, double-blinded study at a single institution.

NCT ID: NCT02274974 Completed - Pain, Postoperative Clinical Trials

Post-Caesarean Section Incisional Infiltration With Lidocaine Versus Lidocaine and Epinephrine

Start date: August 2014
Phase: Phase 4
Study type: Interventional

Study to compare between efficacy of post-caesarean section infiltration with lidocaine and epinephrine versus lidocaine only to reduce post-incisional pain.

NCT ID: NCT02274870 Completed - Post-operative Pain Clinical Trials

Liposomal Bupivacaine for Post Operative Pain After Knee Replacement Surgery

Start date: November 2014
Phase: Phase 4
Study type: Interventional

Continuous femoral nerve blocks (CFNB) provide effective pain control to patients undergoing total knee replacement (TKR). However the resulting motor blockade can lead to decreased quadriceps muscle strength and delayed functional recovery.The purpose of this study is to compare the effect of Liposome Bupivacaine infiltration into the knee to CFNB on pain control and functional recovery

NCT ID: NCT02273999 Completed - Pain Clinical Trials

Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans

Start date: September 2012
Phase: N/A
Study type: Interventional

This randomized clinical trial was designed to assess the clinical efficacy of Pulsed electromagnetic field PEMF delivered with a wearable device in terms of postoperative pain and quality of healing after mandibular third molar extraction. The sample included 120 patients undergoing unilateral mandibular third molar extraction. The devices were positioned over the area corresponding to the extraction site and wearers were asked to keep them in place for 7 days. All patients were asked to record pain (on a visual analog scale [VAS]), hours of wearing the device (groups T and P), and any use of analgesics. At 7 days, healing complications (dehiscence, tumefaction, pus, local lymphadenopathy, pain on palpation, postoperative bleeding, alveolitis) were recorded blindly.

NCT ID: NCT02272660 Completed - Pain, Postoperative Clinical Trials

Parecoxib for Pain Management After Total Knee Arthroplasty and Total Hip Arthroplasty

Start date: October 2014
Phase: Phase 4
Study type: Interventional

Evaluated the effect of perioperative parecoxib administration on postoperative pain, analgesic use, function recovery, inflammatory response and bleeding risk.

NCT ID: NCT02270437 Completed - Pain, Postoperative Clinical Trials

Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee Arthroplasty

Start date: June 2014
Phase: Phase 4
Study type: Interventional

We investigated the safety and efficacy of the bilateral periarticular cocktail injection at a reduced dosage in patients undergoing simultaneous bilateral total knee arthroplasty.

NCT ID: NCT02263963 Completed - Postoperative Pain Clinical Trials

The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.

Start date: July 2013
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the effectiveness of EXPAREL in a transversus abdominis plane block by assessing the demand of postoperative narcotic, length of hospital stay and incidence of postoperative complications.

NCT ID: NCT02263222 Withdrawn - Post-operation Pain Clinical Trials

A Feasibility Dose-escalating Study of MDT-10013 for Acute Postoperative Pain Following Total Knee Arthroplasty

Start date: February 2016
Phase: Phase 2
Study type: Interventional

This is an open-label dose-escalating study to evaluate the tolerability and systemic exposure of MDT-10013 in men and women at least 18 years of age who are undergoing primary unilateral TKA.

NCT ID: NCT02255955 Not yet recruiting - Postoperative Pain Clinical Trials

Postoperative Analgesia in Laminectomy

(PAL)
Start date: October 2014
Phase: Phase 4
Study type: Interventional

Compare the analgesic effects of naproxen sodium codeine, paracetamol codeine and placebo on postoperative pain and tramadol (Contramal) consumption during the first 24 hour after a lumbar disk surgery.

NCT ID: NCT02255591 Completed - Pain, Postoperative Clinical Trials

Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus

Start date: February 2015
Phase: Phase 4
Study type: Interventional

The main objective of the trial is to complete a double-blinded randomized controlled trial of a lumbar plexus block with the Shamrock technique versus the Lumbar Ultrasound Trident technique by estimating the time of performance of lumbar plexus blocks in healthy volunteers. Secondary objectives include a) estimates of number and depth of needle injections, distance of injection site from the midline, minimal electric nerve stimulation to trigger muscular response and the type of response, and volunteer discomfort during block injection, b) measurements of plasma lidocaine and mean arterial blood pressure, c) examinations of sensory block of the dermatomes T8-S3 and motor block of the femoral nerve, the obturator nerve, the hip abductor muscles, and the hamstring muscles, d) success rate of lumbar plexus block, e) perineural and epidural distribution of local anesthetics added contrast visualized on magnetic resonance imaging (MRI) scanning, and f) cost-effectiveness for the Shamrock technique versus the Lumbar Ultrasound Trident Technique for lumbar plexus block in healthy volunteers. The hypothesis is that the Shamrock technique is faster to perform than the Lumbar Ultrasound technique, and that the success rate of the Shamrock technique is equal to or higher than the Lumbar Ultrasound Trident technique.