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Pain, Postoperative clinical trials

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NCT ID: NCT02726126 Completed - Postoperative Pain Clinical Trials

Transdermal Fentanyl and Melatonin Patches for Postoperative Pain Relief

Start date: March 2013
Phase: N/A
Study type: Observational

Seventy five patients, aged 18-50 years, ASA I and II undergoing elective single level lumber laminectomy under general anesthesia were included in this randomized controlled double-blind study. Patients were randomly divided into 3 groups 25 each, C group patients received transdermal placebo patch, TDF group (50μg/h) and TDM group (7 mg). Assessment of postoperative pain, sedation, hemodynamic variables such as HR and MAP, postoperative monitoring of arterial SpO2 and side effects (e.g. nausea, vomiting, pruritis, respiratory depression and hemodynamic instability) were done 30 minutes, 1, 2, 6 and 12 hours postoperatively. Postoperative Patient`s and Surgeons` satisfaction, Intraoperative bleeding and plasma cortisol (µg / dl) postoperatively were also assessed.

NCT ID: NCT02724761 Not yet recruiting - Postoperative Pain Clinical Trials

Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion

Start date: September 2016
Phase: N/A
Study type: Interventional

Our double-blinded, randomized control trial will assess the effect of nebulized racemic epinephrine inpatients undergoing anterior cervical discectomy and fusion (ACDF) procedures. The investigators have had success in managing post-operative dysphagia in patients undergoing ACDF with the administration of this drug. Half of the participants will review nebulized epinephrine. The other half will receive placebo.

NCT ID: NCT02724293 Completed - Clinical trials for Postoperative Pain Following Radical Cystectomy

Efficacy and Safety of Peri-operative Pregabalin After Radical Cystectomy

Start date: September 2014
Phase: Phase 2/Phase 3
Study type: Interventional

This study compares analgesic efficacy, and safety of three different doses of peri-operative pregabaline to placebo following radical cystectomy.

NCT ID: NCT02723487 Completed - Postoperative Pain Clinical Trials

Ultrasound Guided Transversus Abdominis Plane Block in Pediatric Surgery

Start date: April 2016
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess differences in postoperative pain experienced by pediatric patients having transversus abdominis plane block block with bupivacaine (0.125% and 0.25%) compared with control group will receive conventional iv analgesia after Laparoscopic surgery.

NCT ID: NCT02720692 Completed - Clinical trials for Pain, Post-operative

Evaluation of N1539 Following Major Surgery

Start date: March 2016
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the safety and tolerability of N1539 in a variety of post-surgical conditions.

NCT ID: NCT02720406 Completed - Postoperative Pain Clinical Trials

Topical Ketamine Analgesia in Children Undergoing Tonsillectomy: a Clinical and Serum Level Assays Study.

Start date: April 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to evaluate the analgesia efficacy of local ketamine given by two different doses in pediatric patients undergoing tonsillectomy operations

NCT ID: NCT02718976 Completed - Pain, Postoperative Clinical Trials

Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block

Start date: March 2016
Phase: Phase 2
Study type: Interventional

The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs. the Shamrock technique guided by ultrasound in healthy volunteers. The investigators will assess block procedure-related parameters, anatomical spread of local anesthetic, and motor and sensory effects.

NCT ID: NCT02716129 Completed - Postoperative Pain Clinical Trials

The Effect of Adding Nalbuphine to Intrathecal Morphine on Analgesic Efficacy and Side Effects After Cesarean Section

Start date: July 2016
Phase: Phase 2
Study type: Interventional

The primary endpoint of this study is to investigate the effect of adding nalbuphine to intrathecal morphine on quality of postoperative analgesia and Morphine related side effects post- cesarean delivery.

NCT ID: NCT02715999 Completed - Postoperative Pain Clinical Trials

Transversus Abdominis Plane Versus Quadratus Lumborum Block for Pediatrics

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this research study is to find the best way to decrease pain in children whom have had low abdominal surgery. Investigators will perform two technique of trunk block; Transversus abdominis plane or Quadratus lumborum block .The method used is often chosen by which one the doctor has more experience using. The Investigator plans to find out if one of the methods is more effective and/or safer than the other method. The results of this study will help learn how to best control pain in children having surgery low abdominal surgery.

NCT ID: NCT02712749 Completed - Anxiety Clinical Trials

Use of Binaural Beat Premedication in Elderly Submitted to Major Orthopedic Surgery

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The Investigators verify the effectiveness of "Binaural Beats" as premedication instrument in elderly patients submitted to orthopedic surgery to reduce anxiety , post operative pain and morphine consumption