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Pain, Postoperative clinical trials

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NCT ID: NCT02712151 Not yet recruiting - Pain, Postoperative Clinical Trials

Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy

Start date: March 1, 2024
Phase: Phase 3
Study type: Interventional

Laparoscopic cholecystectomy is associated with considerable postoperative pain and surgeon-administered local anesthetic infiltration is the standard practice for achieving post-operative analgesia. However, recent studies have shown that pediatric patients continue to experience significant pain during the first 24 hours. The investigators plan to conduct a prospective, double-blinded, randomized study where patients will be designated into either a test group receiving an ultrasound-guided transversus abdominis plane (TAP) and rectus sheath (RS) blocks with ropivacaine and peri-portal sterile saline or the control group that will receive ultrasound-guided TAP block with sterile saline and peri-portal infiltration of ropivacaine. The anesthesia team and surgical team will both be blinded as well as the research personal in the postoperative period. Patients age 5-17 and American Society of Anesthesiology status I and II undergoing laparoscopic cholecystectomy will be included. The study hypothesis is that ultrasound-guided peripheral nerve blocks, specifically single shot transversus abdominis plane and rectus sheath blocks, are superior to local wound infiltration during laparoscopic cholecystectomy for decreasing postoperative pain and pain related behavior and facilitating functional recovery.

NCT ID: NCT02711592 Terminated - Pain, Postoperative Clinical Trials

Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study

Start date: October 5, 2016
Phase: N/A
Study type: Interventional

The objective of this study is to see how pain management and its outcomes are effected when pharmacogenomic testing is used to determine patient specific pain medication and dosing. Our goal is to determine if through the use of analgesic genetic testing, TKA post-operative patients will see a decrease in narcotic consumption, postsurgical opioid- related adverse reactions, and length of stay, overall NRS pain scores and while maintaining or improving their satisfaction scores.

NCT ID: NCT02711501 Completed - Post-operative Pain Clinical Trials

Comparison of Post-operative Complications of Bone Augmentation at Anterior of Maxilla After Periosteal Releasing Incision With Two Techniques Diode Laser and Scalpel

Start date: March 2016
Phase: N/A
Study type: Interventional

The aim of this study was to investigate if using lasers instead of scalpel for flap advancement in bone augmentation procedures would reduce post-operative swelling and pain.

NCT ID: NCT02707874 Recruiting - Pain, Postoperative Clinical Trials

PIB Versus CI Through a Popliteal Sciatic Nerve Catheter for Analgesia Following Major Ankle Surgery

Start date: October 2014
Phase: Phase 4
Study type: Interventional

This is a clinical study to investigate and compare a new programmed intermittent bolus (PIB) delivery method for continuous popliteal sciatic nerve block for pain relief in patients undergoing major ankle surgery compared with the current practice of continuous local anesthetic infusion (CI).

NCT ID: NCT02704715 Recruiting - Postoperative Pain Clinical Trials

Postoperative Pain in Orbital Disease and Ocular Tumor

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the postoperative pain after general anesthesia of orbital diseases and ocular tumor patients.

NCT ID: NCT02704663 Active, not recruiting - Postoperative Pain Clinical Trials

Transumbilical Versus Lateral Transabdominal Removal of Benign Adnexal Masses Via Laparoscopy

Start date: November 2014
Phase: N/A
Study type: Interventional

In cases of benign adnexal mass laparoscopic surgery, women were randomized to two groups: transumbilical vs. transabdominal removal. Need for pain medication, postoperative pain and patients´ satisfaction were assessed between the groups, as well as surgeons´ opinions and costs.

NCT ID: NCT02703259 Completed - Pain, Postoperative Clinical Trials

Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management

Start date: June 2016
Phase: Phase 4
Study type: Interventional

The purpose of the investigators' study is to assess the efficacy of a single dose of preoperative gabapentin within an enhanced recovery after surgery protocol in acute postoperative pain reduction for women undergoing a minimally invasive hysterectomy. Participants who consent to participate will be randomized to either a control group without gabapentin or to a study arm and receive gabapentin 600 mg prior to their planned surgery. The investigators will collect data on postoperative narcotic use, subjective pain as rated by a numeric pain scale, in addition to any adverse effects of single dose gabapentin use.

NCT ID: NCT02701114 Completed - Post-Operative Pain Clinical Trials

Proximal Versus Distal Adductor Canal Blocks for Total Knee Arthroplasty

Start date: February 2016
Phase: N/A
Study type: Interventional

This study is designed to evaluate pain control of continuous adductor canal blocks placed proximally versus distally within the canal. The investigators hypothesize that there will be similar pain control between both groups.

NCT ID: NCT02698995 Completed - Postoperative Pain Clinical Trials

Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia

Start date: November 2015
Phase: Phase 3
Study type: Interventional

Dexamethasone has an evidence-based indication in postoperative emesis prophylaxy and as a antiinflammatory steroid. Although the perineural administration is off-label, several studies recognised its analgetic action as an adjuvant for peripheral nerves blockade, permitting to reduce the concentration of the local anesthetics and extending the sensory and motor block.Questions remain concerning the mechanism of action, optimal dose, the lack/degree of toxicity and the comparison with intravenous administration.The aim of this prospective randomized controlled study is to investigate the efficacy of analgesia with 4 mg or 2 mg Dexamethasone added to a combination of ropivacaine 0,5% and lidocaine 1% in vertical infraclavicular blockade (VIB) anesthesia for upper limb surgery.

NCT ID: NCT02697955 Completed - Arthritis Clinical Trials

The Effect of Subsartorial Saphenous Block on Postoperative Pain Following Major Ankle and Hind Foot Surgery

Start date: June 21, 2016
Phase: Phase 4
Study type: Interventional

The study investigates the effect of a ultrasound-guided subsartorial saphenous block on postoperative pain following major ankle and hind foot surgery.