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Pain, Postoperative clinical trials

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NCT ID: NCT05513196 Completed - Postoperative Pain Clinical Trials

Bilateral Erector Spinal Plan Block in Postoperative Analgesia After Total Abdominal Hysterectomy

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The importance of effective postoperative pain management is well known. Overall, for total abdominal hysterectomy operations are related with severe postoperative pain. The undesired effects of pain can be prevented with multimodal analgesia for the patient. Many regional anesthesia techniques can be preferred for total abdominal hysterectomy. The aim of this study is to investigate postoperative analgesia effect of erector spina plane block for total abdominal hysterectomy.

NCT ID: NCT05510947 Completed - Post Operative Pain Clinical Trials

Acute Postoperative Pain and Catastrophizing in Patients Undergoing Unicompartmental Knee Arthroplasty

KATUKA
Start date: September 1, 2022
Phase:
Study type: Observational

Advantages of unicompartmental knee arthroplasty (UKA) compared to total knee arthroplasty (TKA) include shorter hospital stays, faster recovery, fewer infections and readmission, and lower costs. It is well documented in TKA-surgery that high pain responders (HPR), evaluated using the Pain Catastrophizing Scale (PCS), have higher postoperative pain responses compared to low pain responders (LPR). These HPR-patients constitute a vulnerable high risk patient group and potentially benefit from targeted treatment. Currently, the distribution of HPR- and LPR-patients and their association with acute pain following UKA is not well investigated. The knowledge that this research project generates is essential to determine how studies with analgesia interventions should be designed. In the future this will contribute in targeting treatment for high risk patient groups to reduce pain and improve postoperative mobilization, and ultimately decrease length of hospital stay in patients undergoing UKA. By targeting treatment, a potential overtreatment is also avoided. The aim of this study is to investigate the prevalence of high- and low-pain responders, defined by a PCS score > 20 and ≤ 20 respectively, as well as the acute postoperative course of pain for these groups after unicompartmental knee arthroplasty.

NCT ID: NCT05508451 Completed - Clinical trials for Postoperative Pain, Acute

Comparison of the Effects of Tenoxicam and Paracetamol on Postoperative Pain

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

Postoperative pain is generally caused by inflammation and oedema related to tissue trauma. Surgical tissue trauma is caused by many factors such as cotery-related burns, surgical incisions, dissections, and instrumental procedures like cutting, stretching, or compression. The pain stimulus is triggered by mediators released by the traumatic tissue and transmitted to the spinal cord and then to the upper centres of the brain. Tenoxicam is an analgesic, anti-inflammatory, and antipyretic drug with a long duration of action, included in the oxicam subgroup of NSAIDs. Tenoxicam has been studied and found effective for many rheumatic diseases such as rheumatoid arthritis, ankylosing spondylitis, gout, extra-articular disorders, bursitis, tendonitis, and osteoarthritis. The primary aim of this study was to compare the effects of tenoxicam, paracetamol, and tenoxicam-paracetamol combination analgesic applications on the postoperative VAS score of double-jaw surgery patients. The secondary aim was to investigate the effects of these interventions on the number of both opioid and rescue analgesic drug consumption postoperatively.

NCT ID: NCT05501977 Completed - Clinical trials for Chronic Pain Syndrome

Retrospective Analysis of Factors Affecting Chronic Postoperative Pain After Thoracotomy

Start date: August 18, 2021
Phase:
Study type: Observational

The aim of this retrospective study is to determine the factors affecting the development of chronic pain in patients with thoracotomy in the Thoracic Surgery Operating Rooms of İbn-i Sina Hospital. By identifying these factors, it is aimed to apply the necessary treatments to prevent the development of chronic pain and to improve patient outcomes.

NCT ID: NCT05498870 Completed - Post Operative Pain Clinical Trials

iPACK for Post-op Pain Following ACL Reconstruction

Start date: July 27, 2022
Phase: Phase 4
Study type: Interventional

This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft. The patients will be randomized to adductor canal block alone, or adductor canal block + iPACK block. The primary goal will be to determine the differences in postoperative pain during the first 72 hours when comparing the two groups. Secondary outcomes will include opioid utilization during the first 72 hours postoperatively and range of motion including terminal knee extension at postoperative follow-up visits.

NCT ID: NCT05494931 Completed - Clinical trials for Reduced Corneal Sensation

Effect of Superficial Keratotomy on Reducing Postoperative Pain Fallowing Conjuctival Flap

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

During conjunctival flap surgery the corneal epithelium is removed and a conjunctival flap is placed on the cornea and after a few weeks the conjunctiva covers the surface of the eye. Complications of this operation are flap retraction, conjunctival inclusion cysts, bleeding, infection and pain. Pain is one of the main complications of conjunctival flap surgery. Two sources are conceivable for pain: 1) conjunctival pain 2) corneal pain, the second of which is the main part of the pain. Numerous methods for controlling corneal pain have been reported in various articles. Eye patches are often recommended for the treatment of corneal abrasions despite the lack of evidence. Recommended analgesics to control corneal scratch pain include nonsteroidal anti-inflammatory drugs (NSAIDs), local anesthetics, and topical cycloplegias. In this article, we are going to review and evaluate a new method called corneal neuorotomy, i.e., corneal nerve endings that inserted radially can be cut to reduce postoperative pain.

NCT ID: NCT05494385 Completed - Postoperative Pain Clinical Trials

Effect of Perioperative Gabapentin on Postoperative Opioid Requirements

Start date: July 27, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if preoperative gabapentin is noninferior to preoperative and postoperative gabapentin for pain control in patients undergoing surgery for pelvic organ prolapse.

NCT ID: NCT05491239 Completed - Lung Cancer Clinical Trials

Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Adequate pain control after video-assisted thoracoscopic surgery (VATS) for lung resection is important to improve postoperative mobilisation, recovery, and to prevent pulmonary complications. So far, no consensus exists on optimal postoperative pain management after VATS anatomic lung resection. Thoracic epidural analgesia (TEA) is the reference standard for postoperative pain management following VATS. Although the analgesic effect of TEA is clear, it is associated with patient immobilisation, bladder dysfunction and hypotension which may result in delayed recovery and longer hospitalisation. These disadvantages of TEA initiated the development of unilateral regional techniques for pain management. The most frequently used techniques are continuous paravertebral block (PVB) and single-shot intercostal nerve block (ICNB). The investigators hypothesize that using either PVB or ICNB is non-inferior to TEA regarding postoperative pain and superior regarding quality of recovery (QoR). Signifying faster postoperative mobilisation, reduced morbidity and shorter hospitalisation, these techniques may therefore reduce health care costs and improve patient satisfaction.

NCT ID: NCT05482919 Completed - Pain Clinical Trials

The Adolescent Surgery Experience: A Mixed Methods Analysis

Start date: June 14, 2022
Phase:
Study type: Observational

New chronic pain and opioid use are reported as prevalent among adolescents undergoing major surgery; many unanswered questions remain regarding recovery and the anticipated pain trajectory across procedures and the interaction between pain treatment, acute inflammation and new chronic pain. Broadly, the proposed study will characterize the adolescent's postoperative recovery experience, and establish the anticipated pain trajectory across a range of procedures.

NCT ID: NCT05480111 Completed - Pain, Postoperative Clinical Trials

The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy

Start date: September 7, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare quality of recovery as well as peri-operative systemic opiates use and pain scores in patients undergoing laparoscopic or robotic hysterectomy when local anesthetic versus Quadratus Lumborum nerve block (QL-2) is added to the standard pain management.