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Pain, Postoperative clinical trials

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NCT ID: NCT05543668 Completed - Pain, Postoperative Clinical Trials

Association of Preoperative Pain With Moderate to Severe Acute Pain After Laparoscopic Cholecystectomy.

Start date: September 16, 2022
Phase:
Study type: Observational

Despite advancement in perioperative pain management, more than half of the patients still report moderate-severe pain after surgery. Among several risk factors, pre-existing pain has consistently been shown to predict postoperative severe pain.If one can predict the patients who will experience more post-operative pain, then a more aggressive pain management strategy can be adopted perioperatively. This would improve patient satisfaction and prevent poor outcomes such as chronic pain after surgery. Therefore, our primary aim is to find out whether presence of pre-existing preoperative pain would predict moderate-severe acute pain after laparoscopic cholecystectomy. Moreover, we plan to use Patient Reported Outcomes Measurement Information System (PROMIS) scale to assess preoperative pain intensity and pain-related behaviors. Primary &Secondary Objectives: Primary objectives To investigate the association between preexisting preoperative pain (more than 3 months duration) and postoperative moderate-severe acute pain after laparoscopic cholecystectomy. Secondary objectives .1. To investigate the association between preoperative PROMIS(patient reported outcome measurement and information system) domain (PROMIS pain intensity score, PROMIS pain interference score, PROMIS pain behavioural score) and postoperative moderate-severe acute pain after LC. 2. To examine baseline demographic, clinical, psycho-behavioural features and intraoperative factors in relation to dynamic moderate to severe pain after LC. 3. To identify perioperative predictors for acute postsurgical pain. 4. To find out the incidence of shoulder tip pain after LC.

NCT ID: NCT05540691 Completed - Postoperative Pain Clinical Trials

Effect of Noise Blocking During General Anesthesia on Postoperative Pain

Start date: October 8, 2022
Phase: N/A
Study type: Interventional

To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery. The aim of this study was to determine whether noise blocking can reduce postoperative pain, analgesic use, and its possible effects on intraoperative electrocorticogram.

NCT ID: NCT05536362 Completed - Colon Cancer Clinical Trials

Propofol With Clonidine and Ketamine Throughout Colon Cancer Surgery

Start date: February 1, 2021
Phase: Phase 1
Study type: Interventional

The Study Showed that combining clonidine and ketamine together can increase the likelihood of achieving a sufficient level of anaesthesia while minimizing post-operative discomfort and inflammation.

NCT ID: NCT05535036 Completed - Postoperative Pain Clinical Trials

Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia

Start date: February 10, 2020
Phase: N/A
Study type: Interventional

The management of postpartum pain is essential to ensure early rehabilitation for parturients. Intravenous dexamethasone has a potent analgesic action when used in the context of general anesthesia. Nevertheless, it remains poorly studied in combination with spinal anesthesia (SA). The aim of this study was to assess the analgesic effect of intravenous dexamethasone after caesarean section under SA. Methods: We conducted a prospective, randomized, double-blinded study including 84 ASA II-III parturient at term who were proposed for caesarean section under SA. Parturient were randomized into two groups: Dexamethasone group (DG) who received 8mg of intravenous dexamethasone (2ml) immediately after SA and placebo group (PG) who received 2ml of isotonic saline. The analgesic protocol was standardized and we opted for Tramadol as rescue analgesic. The main outcome is the use of Tramadol in the first 24 hours postpartum..

NCT ID: NCT05533684 Completed - Pain, Postoperative Clinical Trials

A Single Preoperative Dose of Gabapentin to Decreases Postoperative Pain in Ambulatory Anal Surgeries

Start date: September 1, 2022
Phase: Early Phase 1
Study type: Interventional

Single dose 600 mg gabapentin will be given preoperatively in anal surgeries

NCT ID: NCT05526976 Completed - Clinical trials for Pain, Chronic Post-Surgical

PERIoperative Holistic RIsk Factor SCreening in the Prevention of Persistent Pain

PERISCOPEcare
Start date: December 22, 2022
Phase:
Study type: Observational

Assessment and management for improved wellbeing after elective surgery (PERISCOP³E-Care) Diagnostic assessment tool evaluation and cut-off determination for participation in a transmural perioperative care program

NCT ID: NCT05523102 Completed - Pain, Postoperative Clinical Trials

Paracetamol Compared With Ketorolac for Post-operative Analgetic

Start date: March 31, 2022
Phase: Phase 4
Study type: Interventional

Post-operative analgetic modalities vary between center to center, especially in Indonesia. Considerations include potency/effectivity of the analgetics to achieve adequate pain control as soon as possible, reducing the total opioid dose intake and overall reducing potential opioid adverse effects. NSAID have been known to have more adverse effects than acetaminophen (paracetamol) but offers a higher potency for analgetic effects. Here the investigators compare whether paracetamol is adequate as a post-operative analgetics and confers fewer overall adverse effects when compared with ketorolac (NSAID)

NCT ID: NCT05520580 Completed - Post Operative Pain Clinical Trials

Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of the mother's active pushing during cesarean delivery.

NCT ID: NCT05516901 Completed - Post Operative Pain Clinical Trials

Ultrasound Guided Erector Spinae Plane Block on Post-operative Pain and Diaphragmatic Dysfunction in Epigastric Hernia

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to assess the efficacy of ultrasound guided erector Spinae plane block on postoperative pain score and diaphragmatic dysfunction in obese patients undergoing Epigastric hernia repair.

NCT ID: NCT05514197 Completed - Postoperative Pain Clinical Trials

The Impact of Intravenous Vitamin C Combined With Nerve Blocks on Postoperative Pain and Recovery After Total Knee Arthroplasty

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The aim of this prospective randomized-control study was to evaluate the impact of a single high-dose intravenous vitamin C added to ultrasound-guided blocks at induction on postoperative pain, sngception and early functional rehabilitation of the knee joint in patients under-going total knee arthroplasty.