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Pain, Postoperative clinical trials

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NCT ID: NCT03456141 Completed - Clinical trials for Pain, Post-operative

Multimodal Analgesic Protocol to Moderate Acute Pain

Start date: March 1, 2018
Phase:
Study type: Observational

With a prospective, observational study assess post-surgery pain levels and patient's use of opioids and other analgesic drugs to moderate pain following third molar surgery.

NCT ID: NCT03453866 Completed - Pain, Postoperative Clinical Trials

Effect of Warmed Irrigation in Hip Arthroscopy Undergoing Hip Arthroscopy

Start date: February 9, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if pre-warming of arthroscopic fluid reduces immediate post-surgical pain in hip arthroscopy patients. The investigators hypothesize there will be a significant decrease in the Visual Analog Score (VAS) measured 30 minutes post-operatively in the warmed fluid group compared to the control group. Secondary outcome measures to be collected will include VAS scores 60 minutes after surgery and on post-operative day (POD) one. Additionally, the investigators will collect post-operative temperature measured 30 and 60 minutes post-operatively as well as morphine equivalent dosing in PACU and at the two-week follow up visit.

NCT ID: NCT03450161 Completed - Pain, Postoperative Clinical Trials

Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting

Start date: May 14, 2018
Phase: Phase 4
Study type: Interventional

Randomized, double-blinded, three arm study in adult patients undergoing first time coronary artery bypass grafting (CABG) surgery with median sternotomy. The investigators will examine the effects of three fentanyl dosing schemes (high-dose bolus, low-dose bolus, continuous dose) on the area of hyperalgesia and allodynia at 24 and 48h as well as on persisting pain at 3, 6, and 12 months. Additionally, the investigators will measure fentanyl concentrations throughout anesthesia.

NCT ID: NCT03448263 Completed - Post Operative Pain Clinical Trials

Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.

PEP
Start date: January 4, 2018
Phase: N/A
Study type: Interventional

The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using Balanced Force technique and two reciprocating system when cryotherapy is used. Methodology: All 216 patients had upper or lower molar, premolar or anterior teeth selected for conventional RCT for prosthetic reasons detected with only vital pulps. Of the sample of 216 teeth, were selected to the 3 instrumentation methods. For hand instrumentation, Balanced Force were used. All canals were clean and shaped with hand Flex-R files (fMoyco/Union Broach, York PA, USA). For mechanical shaping, all instruments were used with a micro motor (VDW, Munich Germany). WaveOne and Reciproc instruments. Final irrigation with cold (6oC) 17% EDTA served as a lubricant.

NCT ID: NCT03445390 Completed - Pain Clinical Trials

The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy

Start date: May 1, 2014
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the efficacy of IV acetaminophen when administered to neurosurgical patients at the beginning and end of their surgery. If the result is improved pain control with less opioid consumption postoperatively, then those patients may also experience less opioid related side effects such as nausea/vomiting, pruritus, and sedation. While numerous other studies have failed to show a benefit of IV acetaminophen after neurosurgical procedures, we are studying the administration of 1 g in two doses over the course of the operation.

NCT ID: NCT03444636 Completed - Pain, Postoperative Clinical Trials

Multimodal Analgesia in Children and Adolescents After the Ravitch Procedure and Thoracotomy

Start date: March 2, 2015
Phase: Phase 4
Study type: Interventional

The study was performed in patients aged 6-18 years after the Ravitch procedure and thoracotomy. The primary aim of the study was to evaluate the efficacy and safety of pain control provided by the multimodal approach that involves the continuous infusion ropivacaine with fentanyl vs. bupivacaine with fentanyl through thoracic epidural catheter. Secondary aims were to identify the determinants of acute post-operative pain at rest, during deep breathing and coughing.

NCT ID: NCT03443271 Completed - Postoperative Pain Clinical Trials

Effect of TAP Block on Stress Hormones

Start date: June 17, 2016
Phase: Phase 4
Study type: Interventional

Random allocation of patients in two groups; Tap block group (T group) and control group (C group). All patients will receive standard general anesthesia and postoperative pain management. The TAP group patient will receive ultrasound guided (US) TAP block with 20 cc of 0.25% of bupivacaine and control group will receive 20cc of normal saline. TAP block in both groups will be performed with US guidance and the study drug will be injected after complete visualization of the needle tip between the internal oblique and the transversus abdominis muscles. Venous blood samples (5 ml for each time) for metabolic and stress hormones, including, Serum cortisol and nor-epinephrine will be collected before anesthesia at the time of cannulation (T1),60 minutes after incision(T2), 6hrs (T3)and 12 h (T4) after the surgery. Postoperatively patient will be put on patient controlled intravenous infusion of nalbuphine

NCT ID: NCT03439566 Completed - Pain, Postoperative Clinical Trials

Does Preoperative Pain Levels by Venipuncture Predict Late Postoperative Pain Levels?

Start date: January 15, 2018
Phase:
Study type: Observational

This study wishes to investigate if pain by peripheral venous cannulation (PVC) preoperatively, will predict pain levels after 24 h postoperatively. Furthermore, to investigate moderate/severe pain at the postoperatively at the post-anaesthesia care unit (PACU) is associated with increased late (24h) pain. Additionally, if the PACU nurse is able to predict if the patient will be a high pain responder, by using a clinical judgement. Finally to evaluate the patient's pain-levels at home after discharge and investigate for associations between postoperative pain and post-discharge pain.

NCT ID: NCT03438578 Completed - Pain, Postoperative Clinical Trials

Efficacy Safety Score in Postoperative Management

Start date: March 5, 2018
Phase: N/A
Study type: Interventional

The primary aim of this project is to determine whether postoperative patients may benefit from the Efficacy Safety Score (ESS) as a tool for postoperative clinical decision support, with a special focus on the first 24 hours after discharge from the postoperative care unit.

NCT ID: NCT03437707 Completed - Clinical trials for Postoperative Pain Management

Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery

ibuprofen
Start date: February 13, 2018
Phase: N/A
Study type: Interventional

Primary aim of this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of IV ibuprofen and paracetamol on postoperative pain, and secondary aim is the effects on morphine consumption and side effects of morphine in patients who underwent lumbar disc surgery with a single level laminectomy or discectomy.