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Insulin Resistance clinical trials

View clinical trials related to Insulin Resistance.

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NCT ID: NCT00664495 Completed - Obesity Clinical Trials

Reduction of Abdominal Obesity and Insulin Resistance in Women

Start date: April 1999
Phase: N/A
Study type: Interventional

The purpose of the study was to assess the effects of equivalent diet- or exercise-induced weight loss and related insulin resistance in abdominally obese women.

NCT ID: NCT00664222 Completed - Clinical trials for Chronic Stable Heart Failure

Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF)

Start date: January 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.

NCT ID: NCT00663377 Completed - Heart Failure Clinical Trials

Effects of Losartan on Insulin Resistance in Patients With Heart Failure

Start date: April 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of losartan, an ARB, on glucose metabolism and inflammatory cytokines in CHF patients treated with ACE inhibitors.

NCT ID: NCT00663000 Completed - Diabetes Clinical Trials

Glucose Tolerance in Acromegaly: The Influence of GH-excess on Glucose Metabolism and Insulin Resistance

Start date: April 2008
Phase: N/A
Study type: Observational

Observational, Cross-sectional, longitudinal, multi-center, diagnostic study Cross-sectional part of the study: To evaluate the influence of acromegaly on glucose tolerance Longitudinal part of the study: To evaluate the changes of impaired glucose tolerance during standard treatment of acromegaly. Adult patients with established acromegaly Cross-sectional part of the study: 150 patients Longitudinal part of the study: 58 patients

NCT ID: NCT00657124 Completed - Liver Disease Clinical Trials

Effect of Preoperative Supplementation in Insulin Resistance

Start date: April 2007
Phase: Phase 4
Study type: Interventional

To elucidate the effect of preoperative supplementation of carbohydrate and branched-chain amino acids on postoperative insulin resistance in patients undergoing hepatic resection, we set a randomized trial.

NCT ID: NCT00656851 Completed - HIV Infections Clinical Trials

Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome

WU197
Start date: September 2005
Phase: N/A
Study type: Interventional

We hypothesize that the hearts of HIV+ people with The Metabolic Syndrome use and oxidize fats and sugars inappropriately, and that this may impair the heart's ability to pump blood. We hypothesize that exercise training or pioglitazone (Actos) will improve fat and sugar metabolism in the hearts of HIV+ people with The Metabolic Syndrome. This study will advance our understanding of cardiovascular disease in HIV+ people, and will test the efficacy of exercise training and pioglitazone for improving insulin resistance, heart metabolism and heart function in this at risk population.

NCT ID: NCT00656032 Completed - Clinical trials for End Stage Renal Disease

Vitamin D, Insulin Resistance and Inflammation in ESRD

Start date: April 2008
Phase: Phase 2
Study type: Interventional

The broad goal of this study is to understand the mechanisms by which Vitamin D receptor activation leads to changes in insulin signaling in advanced uremia. We hypothesize that 1,25-Dihydroxyvitamin D3 deficiency due to advanced chronic kidney disease leads to insulin resistance and that administration of a vitamin D3 analog will restore insulin sensitivity in End Stage Renal Disease patients.

NCT ID: NCT00655018 Completed - Inflammation Clinical Trials

Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

VITENAFLD
Start date: January 2003
Phase: Phase 2/Phase 3
Study type: Interventional

No proven treatment exists for nonalcoholic fatty liver disease (NAFLD) in children and adolescents. We aim to determine the efficacy of lifestyle intervention with or without antioxidant therapy in pediatric NAFLD.

NCT ID: NCT00654056 Completed - Clinical trials for Type 2 Diabetes Mellitus

Severe Insulin Resistance in Patients With Type 2 Diabetes

Start date: March 2008
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate some of the mechanisms behind severe insulin resistance and to determine the dose response to insulin in patients with type 2 diabetes mellitus.

NCT ID: NCT00652379 Completed - Insulin Resistance Clinical Trials

Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients

Start date: June 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate if co-treatment of acromegalic patients, who beforehand are considered well-controlled on SA monotherapy, with pegvisomant and SA will improve insulin sensitivity and glucose tolerance, and if these effects of co-treatment can be obtained at a neutral cost as compared to SA mono therapy. Second to investigate body composition, substrate metabolism, symptoms, intrahepatic and intramyocellular fat.