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HIV Infections clinical trials

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NCT ID: NCT00065819 Completed - HIV Infections Clinical Trials

HIV Symptom Management Program for African American Mothers

Start date: September 1996
Phase: Phase 3
Study type: Interventional

African American mothers infected with HIV face unique challenges in management of their disease. The goal of this study was to determine the effectiveness of an HIV self-care and symptom management program designed to help low-income African American mothers with HIV.

NCT ID: NCT00065104 Completed - HIV Infections Clinical Trials

Dehydroepiandrosterone Effects on HIV-1 Replication

Start date: October 2000
Phase: Phase 2
Study type: Interventional

This study's purpose is to learn how dehydroepiandrosterone (DHEA) affects the HIV virus, the immune system, hormone levels, body composition and quality of life.

NCT ID: NCT00064740 Completed - Clinical trials for Human Immunodeficiency Virus

Relaxation Response With Acupuncture for HIV Patients

Start date: July 2003
Phase: Phase 2
Study type: Interventional

Advances in treatment has turned HIV/AIDS into a chronic illness. Relaxation response is a state in which individuals evoke a bodily calm, effecting physiological changes that are shown to be associated with improved immune functioning. Acupuncture and relaxation are thought to both induce calm and deep relaxation in mind and body. This trial will study the combined effects of acupuncture and relaxation response in HIV patients.

NCT ID: NCT00064623 Completed - Pain Clinical Trials

Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy

Start date: August 2003
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if an investigational drug, NGX-4010 (high-concentration capsaicin patch), is effective in treating painful HIV-associated neuropathy.

NCT ID: NCT00063804 Completed - HIV Infections Clinical Trials

Safety of AMD070 When Administered Alone or Boosted With Low-Dose Ritonavir in HIV Uninfected Men

Start date: n/a
Phase: Phase 1
Study type: Interventional

Most currently approved anti-HIV drugs work by stopping the replication of HIV after it has entered cells. AMD070 (also known as AMD11070) is designed to block HIV from entering cells and may be effective in treating patients who have developed resistance to or are unable to take other anti-HIV drugs. This study will evaluate the safety of different doses of AMD070 along with AMD070 boosted with ritonavir (RTV) in HIV uninfected men.

NCT ID: NCT00063778 Completed - HIV Infections Clinical Trials

Safety of an HIV Vaccine (AVX101) in HIV Uninfected Volunteers in the United States and South Africa

Start date: July 2003
Phase: Phase 1
Study type: Interventional

The purpose of this study is to see if different doses of an experimental HIV vaccine are safe and to study how the immune system responds to the vaccine. The vaccine will be tested in healthy, HIV uninfected volunteers. AVX101 contains only one of the many substances that HIV needs to make more copies of itself; therefore, the vaccine cannot cause HIV or AIDS.

NCT ID: NCT00061321 Completed - HIV Infections Clinical Trials

Daily Nevirapine to Prevent Mother to Infant Transmission of HIV

SWEN
Start date: August 2002
Phase: Phase 3
Study type: Interventional

Infants who are breast-fed by HIV infected mothers have an increased risk of becoming infected with HIV. Standard therapy for the prevention of HIV infections in infants included zidovudine (ZDV) prior to the onset of labor, a single dose of nevirapine (NVP) for women during labor, and a single dose of NVP for newborns given 72 hours after birth. This study will determine if giving low dose daily NVP to breastfed infants of HIV infected mothers, in addition to standard therapy, will be more effective than standard therapy alone at preventing HIV infections in these infants.

NCT ID: NCT00061256 Completed - HIV Infections Clinical Trials

The Effect of Alendronate, Calcium, and Vitamin D on Bone Mineral Density in HIV Infected Patients

Start date: n/a
Phase: Phase 2
Study type: Interventional

Alendronate is a drug that is used to treat osteoporosis. The purpose of this study is to examine whether alendronate in combination with calcium and vitamin D is safe and effective for treating bone loss in people with HIV.

NCT ID: NCT00059462 Completed - HIV Infections Clinical Trials

Safety and Efficacy of BAY 50-4798 in Patients With HIV Infection

Start date: December 2002
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety of the experimental drug Bay 50-4798 in HIV positive patients receiving HAART and to test the drug's effect on the CD4+ T-cell count.

NCT ID: NCT00059384 Completed - HIV Infections Clinical Trials

Alternative Dosing Strategy for Anti-HIV Drugs

Start date: January 2003
Phase: Phase 4
Study type: Interventional

Anti-HIV drugs are usually given to patients at fixed, standardized doses. This study will investigate alternative ways of dosing anti-HIV drugs to improve viral control. Study hypothesis: The optimal dosage regimen required to obtain the maximum benefit from antiretroviral therapy is achieved with strategies that control for pharmacokinetic and pharmacodynamic variability among patients.