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Heart Failure clinical trials

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NCT ID: NCT02877914 Recruiting - Heart Failure Clinical Trials

China PEACE 5r-HF Study

Start date: September 2016
Phase: N/A
Study type: Observational

This study will use a two-stage random sampling design to create a nationally representative sample of patients with heart failure (HF) in China. The investigators sought to describe the clinical profiles, to assess treatment patterns and in-hospital outcomes for HF, and to identify targets for care quality improvement.

NCT ID: NCT02876042 Recruiting - Heart Failure Clinical Trials

BAROSTIM THERAPY™ In Heart Failure With Preserved Ejection Fraction

HFpEF
Start date: March 23, 2017
Phase:
Study type: Observational [Patient Registry]

The purpose of this registry (NCT02876042) is to evaluate the effect of BAROSTIM THERAPY with the BAROSTIM NEO system in the commercial setting in subjects recently implanted under the CE-Marked indication for resistant hypertension that also have evidence of heart failure with preserved ejection fraction (HFpEF).

NCT ID: NCT02875639 Recruiting - Clinical trials for Ischemic Heart Failure

A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome)

Start date: June 2016
Phase: Phase 2
Study type: Interventional

The main purpose of this research is to reveal the curative effect mechanism of Yiqihuoxue prescription which treat the disease of qi deficiency and blood stasis. And at the same time this study also try to confirm yiqi huoxue fang qi deficiency blood stasis treatment of coronary heart disease (CHD) heart failure the curative effect and security.

NCT ID: NCT02871466 Recruiting - Clinical trials for Congestive Heart Failure

Stem Cells Therapy in Advanced Heart Failure

Start date: January 2010
Phase: Phase 4
Study type: Interventional

stem cells therapy may be a choice therapy for advanced heart failure patients refractory to medical therapy, internal cardiovertor with a defibrillator (ICD) recipients, and a previous history of myocardial infarction and coronary artery revascularization. These patients, without indication to receive a cardiac resynchronization therapy (CRT), may have a worsening of heart failure, and symptoms of coronary artery disease. In this study we have evaluated in consecutive 30 selected patients the amelioration in failing heart NYHA class, hospitalization rate, echocardiographic left ventricle functionality, and associated to reduction of angina after a treatment with stem cells intra thoracic infusion.

NCT ID: NCT02869178 Recruiting - Heart Failure Clinical Trials

Strain X Cardiopulmonary Test

Start date: August 2016
Phase: N/A
Study type: Observational

Introduction : Patients with heart failure (HF ) with systolic dysfunction of moderate to severe exhibit significant reduction in the ability to exercise compared to those with mild dysfunction , and have worse prognosis. However, some clinical markers of severity and diagnosis widely used in this population such as ejection fraction (EF) , are not always able to translate the actual degree of cardiac damage as well as their relationship with the cardiorespiratory fitness of these individuals and prognosis . Objective: To evaluate the ability of the global longitudinal strain ( GLS ) in predicting exercise tolerance in heart failure patients with moderate and significant systolic dysfunction.

NCT ID: NCT02862600 Recruiting - Clinical trials for Cardiomyopathy, Hypertrophic

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Start date: August 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of perhexiline on exercise performance (efficacy) and safety in patients with hypertrophic cardiomyopathy and moderate-to-severe heart failure following dosing for 16 weeks.

NCT ID: NCT02862197 Recruiting - Clinical trials for End Stage Renal Disease

Invasive Monitoring of Pulmonary Artery Pressure (PAP) Among Dialysis Treated Patients

Start date: November 2016
Phase: N/A
Study type: Observational

The purpose of this study is examine whether invasive pulmonary artery pressure (PAP) monitoring could be beneficial for the patients in dialysis treatment. Ten implantable pressure sensors (CardioMEMS ®) will be implanted and the PAPs of the individual participants are recorded during and in between the routine dialysis treatment sessions. This is an exploratory pilot study, where major interest lies in the values and changes in PAP in relation to other hemodynamic parameters among patients in dialysis treatment. Implanted device is only monitoring the patient without any effect on the actual treatment.

NCT ID: NCT02856620 Recruiting - Heart Failure Clinical Trials

The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis

SCRABLES
Start date: July 2016
Phase:
Study type: Observational

The role of cardiac mechanics, circulating biomarkers and frailty in predicting outcomes in patients with aortic stenosis after aortic valve replacement (SCRABLES -The 2-Parts Study) Part I: Observational study to characterize phenotypes, structural alterations and biomarkers profiles in a broad spectrum of patients with aortic stenosis and heart failure with preserved ejection fraction (HFpEF). Part II: Prospective cohort study to characterize patients' phenotypes, cardiac structural alterations, circulating biomarkers and frailty in order to optimize risk stratification and patient selection for aortic valve intervention.

NCT ID: NCT02831881 Recruiting - Heart Failure Clinical Trials

Protected PCI Study

Start date: November 2015
Phase: N/A
Study type: Observational

A Prospective, multi-center, single-arm post-approval study of the IMPELLA® 2.5 System in Non Emergent High Risk PCI patients.

NCT ID: NCT02829450 Recruiting - Clinical trials for Chronic Kidney Disease

Peritoneal Ultrafiltration to Treat Congestive Heart Failure

Start date: October 2015
Phase: Phase 0
Study type: Observational

The purpose of this study is to determine whether the treatment of peritoneal ultrafiltration can improve survival and quality of life of refractory congestive heart failure with special accent on preserving residual renal function and peritoneal membrane characteristics/