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NCT ID: NCT05727774 Completed - Healthy Clinical Trials

Effect of Water Biking in Hot Versus Neutral Water for Heat Acclimatation

THERMIDOR
Start date: February 8, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the efficiency of water biking training in hot (35°C) versus neutral (25°C) temperature water to elicite heat acclimation in healthy recreative athletes.

NCT ID: NCT05727189 Recruiting - Healthy Clinical Trials

A Study of Idazoxan in Healthy Participants

Start date: February 14, 2023
Phase: Phase 1
Study type: Interventional

Four-part study of the safety, tolerability and pharmacokinetics of 3 forms of TR-01-XRR, 1 form of TR-01-XRS, and 1 form of TR-01-XR in healthy adults.

NCT ID: NCT05727072 Completed - Healthy Clinical Trials

A Study of LY3848575 in Healthy Participants

Start date: February 10, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and tolerability of LY3848575 when administered either intravenously or subcutaneously in single ascending or multiple doses in healthy non-Japanese and first generation Japanese participants. The study will also assess how fast LY3848575 gets into the blood stream and how long it takes the body to remove it. The study is open to healthy participants. The study will last up to approximately 142 days excluding the screening period of 28 days.

NCT ID: NCT05725811 Completed - Healthy Clinical Trials

Immediate Effects of Myofascial Release on the Quadriceps or Hamstrings on Active Cervical Range of Motion

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to verify the immediate effects of quadriceps or hamstring myofascial release on the active cervical flexion and extension range of motion.

NCT ID: NCT05725005 Completed - Healthy Clinical Trials

PET Study of Repeated ASN51 in Healthy Volunteers

Start date: January 26, 2023
Phase: Phase 1
Study type: Interventional

This is a phase 1, open-label, dose escalation, PET study to investigate the brain occupancy of O-GlcNAcase, and the PD response in PBMCs, after repeated doses of ASN51 in healthy subjects.

NCT ID: NCT05723913 Recruiting - Healthy Clinical Trials

Postprandial Glucose Levels, Gut Microbiota and Supplementation With Functional Foods in Adults

PPGR
Start date: June 7, 2023
Phase: N/A
Study type: Interventional

This is a clinical study with participants over 18 years of age that meet the selection criteria. This will be 42-day study divided into three phases of 14 days each: 14 days without intervention, 14 days with intervention with functional foods and 14 days without intervention again. With the objective of assess the changes in the postprandial glycemic responses through the gut microbiota and urine metabolites.

NCT ID: NCT05723874 Completed - Healthy Clinical Trials

A Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the Blood

Start date: March 6, 2023
Phase: Phase 1
Study type: Interventional

The main objective of this trial is to investigate the relative bioavailability of BI 425809 given alone (Reference) compared to a combined administration with the moderate CYP3A4 inducer bosentan (Test) following repeated oral administration.

NCT ID: NCT05723549 Completed - Healthy Clinical Trials

A Study to Evaluate the PK, Safety and Tolerability of HCP1803.

Start date: February 2, 2023
Phase: Phase 1
Study type: Interventional

A randomized, open-label, single-dose parallel study to evaluate the pharmacokinetics, safety and tolerability of HCP1803 in healthy male volunteers.

NCT ID: NCT05723510 Completed - Healthy Clinical Trials

PK and PD Interaction Between Tegoprazan and NOACs After Multiple Oral Dosing in Healthy Volunteers

Start date: March 6, 2023
Phase: Phase 1
Study type: Interventional

This study aims to evaluate the effects of combination therapy of tegoprazan and novel oral anticoagulants (NOACs) on the pharmacokinetic and pharmacodynamic properties of NOACs in healthy adults.

NCT ID: NCT05722262 Completed - Healthy Clinical Trials

Study to Demonstrate the Bioequivalence of Single Oral Administration of K-001 Relative to Single Oral Coadministration of Separate Tablets of K-877-ER and CSG452

Start date: February 24, 2023
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to demonstrate the bioequivalence of single oral administration of K-001 relative to single oral co-administration of separate tablets of K-877-ER and CSG452 in healthy adult volunteers, and to characterize the food effect on the Pharmacokinetics(PK) of K-001.