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NCT ID: NCT03736148 Completed - Healthy Clinical Trials

Effects of Manual vs Instrument-assisted Manipulation on Electromyographic Activity and Sympathetic Nervous System

Start date: January 20, 2015
Phase: N/A
Study type: Interventional

This study evaluates the effects of manual and instrument-assisted cervical manipulation on electromyographic activity and sympathetic nervous system. Subjects were divided in four groups, one group was submitted to a manual cervical manipulation, other group was submitted to an instrument-assisted cervical manipulation, other group was submitted to a sham manipulation and another group served as control.

NCT ID: NCT03728751 Completed - Healthy Clinical Trials

Optimal Time for In-situ Dry Needling to Affect the Autonomic Nervous System

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Assessing for optimal time dry needles need to remain inside the body to have positive effect on the nervous system

NCT ID: NCT03714295 Completed - Healthy Clinical Trials

Impact of Interdental Brushing on the Evolution of Supra-gingival Bacterial Flora (BACTERIB)

Start date: April 1, 2015
Study type: Observational [Patient Registry]

In France, two-thirds of adults over 35 years of age have at least a periodontal disease. The etiology is the accumulation of dental plaque, especially in interdental spaces. The cleaning of interdental spaces is particularly complex. This accumulation of dental plaque is at the origin of a modification of the bacterial flora in favor of periodontopathogenic bacteria. These pathogens can induce within the periodontal tissues an immune and inflammatory reaction that cause tissue degradation. The majority of studies focus on people over 30 years of age with gingivitis or periodontitis. However, young adults, in whom the initial or even reversible stages of periodontal disease are the most frequent, should be the preferred target of preventive measures for this pathology. The main objective of this study is to quantify, in healthy patients, the evolution of the supragingival bacterial flora, in the interdental spaces, following the daily passage of brushes with the adapted diameter and single passage. The secondary objective is to evaluate the qualitative change in the bacterial flora (proportions of periodontal bacteria / commensal bacteria) following the interdental cleaning.

NCT ID: NCT03713164 Completed - Healthy Clinical Trials

The Effects of Ellagic Acid From Pomegranate Juice vs. Pure Ellagic Acid on Healthy Male Subjects

Start date: February 22, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this research study is to compare the extent of polyphenol absorption in the body in normal healthy male volunteers when consuming either pomegranate juice or pure ellagic acid, an ellagitannin naturally present in pomegranates. Polyphenols are naturally occurring chemicals found in plant based food that serve to reduce inflammation and damage to cells. You will be asked to avoid foods rich in polyphenols including dark chocolate and cocoa products, dried herbs, berries, coffee, tea, flaxseeds, nuts (chestnut, hazelnut), olive and artichoke. Timed urine collections will be used to measure the metabolism of polyphenols through the presence and concentration of urolithin and ellagic acid metabolites. Additionally, it has been demonstrated in animal studies that fruits and vegetables, which are high in antioxidants and fiber, lead to improvement of gut health, inflammation and glucose tolerance. However, no information is available about the effect of ellagitanins on the gut microbiome (bacteria in the intestines).

NCT ID: NCT03710577 Completed - Healthy Clinical Trials

Endocannabinoid and Psychological Responses to Yoga in Healthy Adults

Start date: December 12, 2017
Phase: N/A
Study type: Interventional

This study evaluates the acute effect of yoga on plasma levels of endocannabinoids and mood (i.e., mood disturbance, anxiety, pain) compared to one session of quiet rest. Participants completed one session of yoga and one session of quiet rest on two separate days.

NCT ID: NCT03707002 Completed - Healthy Clinical Trials

Effect of scFOS on Increase in Stool Frequency in Constipated People

Start date: October 2015
Phase: N/A
Study type: Interventional

The study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.

NCT ID: NCT03706781 Completed - Healthy Clinical Trials

A Novel Mouthwash Formulation CTP/BNZ With Mucus Adhesive Polymer

Start date: November 14, 2017
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the local tolerability and the systemic availability of benzydamine, if any, after single and multiple dose treatment with the test formulation containing cetylpyridinium chloride 0.05% + benzydamine hydrochloride 0.15% + mucoadhesive polymer and with the reference formulation Tantum Verde Bocca containing cetylpyridinium chloride 0.05% + benzydamine hydrochloride 0.15% to healthy subjects , under fasting conditions, in two consecutive study periods.

NCT ID: NCT03706300 Completed - Healthy Clinical Trials

Bioequivalence Study of Guaifenesin and Pseudoephedrine Hydrochloride Extended Release Tablets 1200/120 mg Under Fasting Conditions

Start date: December 2014
Phase: Phase 1
Study type: Interventional

This is an open label, balanced, randomized, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study in healthy, adult, human subjects under fasting conditions.

NCT ID: NCT03705572 Completed - Healthy Clinical Trials

Intervention Study Investigating the Effect of a Phospholipid Drink on Cognitive Performance in 6-8 Year Old School Children

Start date: May 2014
Phase: N/A
Study type: Interventional

Six week RCT intervention on the effects of phospholipid containing milk drink vs. placebo milk drink on cognitive performance in 6-8 year old school children.

NCT ID: NCT03704337 Completed - Healthy Clinical Trials

Effects Of Ingesting An Energy Bar On Performance And Recovery

Start date: December 13, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects of ingesting a low glycemic whey protein energy bar prior, during and following resistance exercise and conditioning on performance and recovery.