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NCT ID: NCT03655873 Enrolling by invitation - Healthy Clinical Trials

The Study of a Selective 5-ht6 Receptor Antagonist, HEC30654AcOH,in Healthy Subjects

Start date: September 23, 2018
Phase: Phase 1
Study type: Interventional

This study is a safety, tolerability, and pharmacokinetics phase Ⅰstudy of a selective 5-ht6 receptor antagonist, HEC30654AcOH,in healthy subjects.This test is divided into two parts, the first part is the healthy adult subjects single ascending-dose research;The second part is the healthy adult subjects multiple ascending-dose research.

NCT ID: NCT03575312 Enrolling by invitation - Healthy Clinical Trials

Pharmacokinetics of Enrofloxacin in Plasma and Urine

EnroHuman
Start date: April 27, 2018
Phase: N/A
Study type: Interventional

Antibiotics like enrofloxacin are widely used in animal farming to treat and prevent bacterial infections. A previous study in poultry farms has shown that yardmen show significant concentrations of administered antibiotics in their urine. It is currently unclear how poultry yardmen are exposed to the administered antibiotics. The objective of this exemplarily study is to obtain information on the pharmacokinetics of the different uptake routes (oral, inhaled or dermal).

NCT ID: NCT03574285 Enrolling by invitation - Healthy Clinical Trials

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Feeding Conditions

Start date: May 31, 2018
Phase: Phase 1
Study type: Interventional

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Feeding Conditions

NCT ID: NCT03573622 Enrolling by invitation - Healthy Clinical Trials

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fasting Conditions

Start date: May 31, 2018
Phase: Phase 1
Study type: Interventional

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fasting Conditions

NCT ID: NCT03524066 Enrolling by invitation - Healthy Clinical Trials

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Start date: April 10, 2018
Phase: N/A
Study type: Interventional

The aim of the present study is to increase the general understanding of lung PK of selected compounds by sampling epithelial lining fluid ELF and lung tissue.

NCT ID: NCT03485313 Enrolling by invitation - Healthy Clinical Trials

Beta-hCG Test Reference Range Determination

Start date: April 25, 2018
Phase:
Study type: Observational

Prospective, single-centre study to determine the reference range (95th percentile) of human chorionic gonadotropin (hCG) levels in a healthy, non-pregnant, adult female population using the RAMP® Total β-hCG test.

NCT ID: NCT03482726 Enrolling by invitation - Healthy Clinical Trials

Cadence Modulation in Cyclists

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

This study will utilize a combination of cardiovascular analysis, 3D motion capture, and a software package, Metrifit, to monitor measures of well-being to comprehensively evaluate both the musculoskeletal and physiological responses following a HIIT training intervention at EOC as a means of improving performance and potentially reducing injury risk factors. This holistic approach of physiological and biomechanical factors is unprecedented. This is the first interventional study to determine the effect of high intensity training at EOC on cardiovascular performance, kinematics and well-being which may minimize risk of injury factors.

NCT ID: NCT03435055 Enrolling by invitation - Healthy Clinical Trials

Network-Level Effects of Nitrous Oxide in the Human Brain

Start date: July 21, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to understand how a commonly used drug, nitrous oxide, acts on the brain to reduce pain. Nitrous oxide is commonly used in anesthesiology but there is limited knowledge on how this drug affects functional networks in the brain.

NCT ID: NCT03384771 Enrolling by invitation - Healthy Clinical Trials

Predictors of Outcomes in MBSR Participants From Teacher Factors

Prompt-F
Start date: January 2017
Phase: N/A
Study type: Observational

Objectives. The primary objective of the current proposal is to identify teacher-related factors that can be feasibly measured and shown to predict mindfulness-based intervention (MBI) participant outcomes. The secondary objective of this R34 proposal is to lay the groundwork for a large-scale R01-funded study in which the investigators anticipate studying participants in Mindfulness-Based Stress reduction (MBSR) courses provided by 50 or more teachers in a range of university- and community-based settings.

NCT ID: NCT03361605 Enrolling by invitation - Healthy Clinical Trials

Neuroimaging of Anesthetic Modulation of Human Consciousness

Start date: April 12, 2017
Phase: Phase 4
Study type: Interventional

This study's purpose is to see if mental functions take place during different levels of anesthesia, using a commonly used drug (Propofol). fMRI (functional Magnetic Resonance Imaging, or "brain imaging") shows areas in the brain involved in thinking at different depths of anesthesia.