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NCT ID: NCT03524066 Enrolling by invitation - Healthy Clinical Trials

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Start date: April 10, 2018
Phase: N/A
Study type: Interventional

The aim of the present study is to increase the general understanding of lung PK of selected compounds by sampling epithelial lining fluid ELF and lung tissue.

NCT ID: NCT03482726 Enrolling by invitation - Healthy Clinical Trials

Cadence Modulation in Cyclists

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

This study will utilize a combination of cardiovascular analysis, 3D motion capture, and a software package, Metrifit, to monitor measures of well-being to comprehensively evaluate both the musculoskeletal and physiological responses following a HIIT training intervention at EOC as a means of improving performance and potentially reducing injury risk factors. This holistic approach of physiological and biomechanical factors is unprecedented. This is the first interventional study to determine the effect of high intensity training at EOC on cardiovascular performance, kinematics and well-being which may minimize risk of injury factors.

NCT ID: NCT03447847 Enrolling by invitation - Healthy Clinical Trials

Effect of Composition and Timing of Ingestion of Fluids on the Urinary Excretion of Lithogenic Substances

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Interventional crossover study on healthy volunteers aimed at evaluating the effect of the composition and timing of ingestion of different types of water on the urinary excretion of lithogenic substances; the study will also analyze the effect of potassium citrate on urine pH and lithogenic substances

NCT ID: NCT03435055 Enrolling by invitation - Healthy Clinical Trials

Network-Level Effects of Nitrous Oxide in the Human Brain

Start date: July 21, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to understand how a commonly used drug, nitrous oxide, acts on the brain to reduce pain. Nitrous oxide is commonly used in anesthesiology but there is limited knowledge on how this drug affects functional networks in the brain.

NCT ID: NCT03409445 Enrolling by invitation - Healthy Clinical Trials

Validation of a Food Frequency Questionnaire for the Assessment of Omega-3 Fatty Acid Intake

Start date: January 15, 2018
Phase:
Study type: Observational

As essential nutrients omega 3 fatty acids contribute to normal growth and development. Inadequate intake is linked to the development of chronic diseases such as coronary heart disease, high blood pressure, cancer, arthritis, psychological illnesses and allergies. Therefore, it is important to be able to reliably detect the intake of these fatty acids. Due to eating habits varying in different countries the questionnaire documenting dietary habits needs to be adapted to the situation in question. Based on a US version the investigators developed a questionnaire suitable for Switzerland and now wish to validate it by measuring the fatty acid composition of red blood cells, which will provide information on the intake of the various fatty acids.

NCT ID: NCT03384771 Enrolling by invitation - Healthy Clinical Trials

Predictors of Outcomes in MBSR Participants From Teacher Factors

Prompt-F
Start date: January 2017
Phase: N/A
Study type: Observational

Objectives. The primary objective of the current proposal is to identify teacher-related factors that can be feasibly measured and shown to predict mindfulness-based intervention (MBI) participant outcomes. The secondary objective of this R34 proposal is to lay the groundwork for a large-scale R01-funded study in which the investigators anticipate studying participants in Mindfulness-Based Stress reduction (MBSR) courses provided by 50 or more teachers in a range of university- and community-based settings.

NCT ID: NCT03361605 Enrolling by invitation - Healthy Clinical Trials

Neuroimaging of Anesthetic Modulation of Human Consciousness

Start date: April 12, 2017
Phase: Phase 4
Study type: Interventional

This study's purpose is to see if mental functions take place during different levels of anesthesia, using a commonly used drug (Propofol). fMRI (functional Magnetic Resonance Imaging, or "brain imaging") shows areas in the brain involved in thinking at different depths of anesthesia.

NCT ID: NCT03351452 Enrolling by invitation - Healthy Clinical Trials

tES Effects on Associative Memory Performance

Start date: April 9, 2018
Phase: N/A
Study type: Interventional

Previous studies showed that transcranial electric stimulation (tES) applied over the prefrontal cortex improves cognitive performance in healthy elderly adults as well as in patients suffering from mild cognitive impairment or early Alzheimer's disease. Therefore, tES methods might be a useful intervention tool for patients suffering from memory impairment in early terms of the disease. The present study aims at establishing a connection between the stimulation-induced changes on associative memory performance and its underlying neurophysiological parameters. tES effects and their underlying mechanisms will be compared between healthy elderly controls and clinical study populations receiving either real or sham tES over the left ventrolateral prefrontal cortex during an associative memory task.

NCT ID: NCT03333135 Enrolling by invitation - Healthy Clinical Trials

Ultramarathons and Impact of Phased Electromagnetic Field Therapy (PEMF)

Start date: December 12, 2016
Phase: N/A
Study type: Interventional

This research is being done to better understand the pulmonary consequences of completing an ultra marathon at altitude and a sea level city.

NCT ID: NCT03319446 Enrolling by invitation - Healthy Clinical Trials

Collection of Anonymized Samples

Start date: October 9, 2017
Phase: N/A
Study type: Observational

This is a generic sample collection study for collecting blood, stool, rectal swabs, nasal washes, nasopharyngeal aspirates, nasopharyngeal swabs, throat swabs, nasal swabs, and urine from human sources. Subjects will be recruited from BioFire Diagnostics employees and from the general community. Subjects may be asked about recent or ongoing illness at the time of specimen collection and these symptoms will be recorded and attached to the sample. No other identifying information will be collected and the samples will be kept anonymous.The samples may be used internally or by external sites, such as the clinical study sites, for evaluating and determining performance characteristics of in vitro diagnostic devices.