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NCT ID: NCT03575312 Enrolling by invitation - Healthy Clinical Trials

Pharmacokinetics of Enrofloxacin in Plasma and Urine

EnroHuman
Start date: April 27, 2018
Phase: N/A
Study type: Interventional

Antibiotics like enrofloxacin are widely used in animal farming to treat and prevent bacterial infections. A previous study in poultry farms has shown that yardmen show significant concentrations of administered antibiotics in their urine. It is currently unclear how poultry yardmen are exposed to the administered antibiotics. The objective of this exemplarily study is to obtain information on the pharmacokinetics of the different uptake routes (oral, inhaled or dermal).

NCT ID: NCT03574285 Enrolling by invitation - Healthy Clinical Trials

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Feeding Conditions

Start date: May 31, 2018
Phase: Phase 1
Study type: Interventional

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Feeding Conditions

NCT ID: NCT03573622 Enrolling by invitation - Healthy Clinical Trials

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fasting Conditions

Start date: May 31, 2018
Phase: Phase 1
Study type: Interventional

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fasting Conditions

NCT ID: NCT03524066 Enrolling by invitation - Healthy Clinical Trials

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Start date: April 10, 2018
Phase: N/A
Study type: Interventional

The aim of the present study is to increase the general understanding of lung PK of selected compounds by sampling epithelial lining fluid ELF and lung tissue.

NCT ID: NCT03482726 Enrolling by invitation - Healthy Clinical Trials

Cadence Modulation in Cyclists

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

This study will utilize a combination of cardiovascular analysis, 3D motion capture, and a software package, Metrifit, to monitor measures of well-being to comprehensively evaluate both the musculoskeletal and physiological responses following a HIIT training intervention at EOC as a means of improving performance and potentially reducing injury risk factors. This holistic approach of physiological and biomechanical factors is unprecedented. This is the first interventional study to determine the effect of high intensity training at EOC on cardiovascular performance, kinematics and well-being which may minimize risk of injury factors.

NCT ID: NCT03447847 Enrolling by invitation - Healthy Clinical Trials

Effect of Composition and Timing of Ingestion of Fluids on the Urinary Excretion of Lithogenic Substances

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Interventional crossover study on healthy volunteers aimed at evaluating the effect of the composition and timing of ingestion of different types of water on the urinary excretion of lithogenic substances; the study will also analyze the effect of potassium citrate on urine pH and lithogenic substances

NCT ID: NCT03435055 Enrolling by invitation - Healthy Clinical Trials

Network-Level Effects of Nitrous Oxide in the Human Brain

Start date: July 21, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to understand how a commonly used drug, nitrous oxide, acts on the brain to reduce pain. Nitrous oxide is commonly used in anesthesiology but there is limited knowledge on how this drug affects functional networks in the brain.

NCT ID: NCT03409445 Enrolling by invitation - Healthy Clinical Trials

Validation of a Food Frequency Questionnaire for the Assessment of Omega-3 Fatty Acid Intake

Start date: January 15, 2018
Phase:
Study type: Observational

As essential nutrients omega 3 fatty acids contribute to normal growth and development. Inadequate intake is linked to the development of chronic diseases such as coronary heart disease, high blood pressure, cancer, arthritis, psychological illnesses and allergies. Therefore, it is important to be able to reliably detect the intake of these fatty acids. Due to eating habits varying in different countries the questionnaire documenting dietary habits needs to be adapted to the situation in question. Based on a US version the investigators developed a questionnaire suitable for Switzerland and now wish to validate it by measuring the fatty acid composition of red blood cells, which will provide information on the intake of the various fatty acids.

NCT ID: NCT03384771 Enrolling by invitation - Healthy Clinical Trials

Predictors of Outcomes in MBSR Participants From Teacher Factors

Prompt-F
Start date: January 2017
Phase: N/A
Study type: Observational

Objectives. The primary objective of the current proposal is to identify teacher-related factors that can be feasibly measured and shown to predict mindfulness-based intervention (MBI) participant outcomes. The secondary objective of this R34 proposal is to lay the groundwork for a large-scale R01-funded study in which the investigators anticipate studying participants in Mindfulness-Based Stress reduction (MBSR) courses provided by 50 or more teachers in a range of university- and community-based settings.

NCT ID: NCT03361605 Enrolling by invitation - Healthy Clinical Trials

Neuroimaging of Anesthetic Modulation of Human Consciousness

Start date: April 12, 2017
Phase: Phase 4
Study type: Interventional

This study's purpose is to see if mental functions take place during different levels of anesthesia, using a commonly used drug (Propofol). fMRI (functional Magnetic Resonance Imaging, or "brain imaging") shows areas in the brain involved in thinking at different depths of anesthesia.