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NCT ID: NCT03196804 Recruiting - Healthy Clinical Trials

A Multiple Dosing and Dose-escalation Phase I Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetic Characteristics of LC28-0126 in Healthy Male Subjects

Start date: June 7, 2017
Phase: Phase 1
Study type: Interventional

To assess the safety, tolerability and pharmacokinetic characteristics of LC-28-0126 multiple iv injection in healthy male subjects.

NCT ID: NCT03182920 Recruiting - Healthy Clinical Trials

A Study of Lasmiditan in Healthy Participants

Start date: June 16, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to look at the amount of study drug that gets into the blood stream and how long it takes the body to get rid of it by comparing the results of healthy elderly participants to those of healthy young participants. The tolerability of the study drug will be evaluated. Information about any side effects that may occur will also be collected. This study will last up to approximately 19 days, not including screening. This study requires either one (Group 2) or two (Group 1) stays at the clinic each of at least four days/three nights. Participants will return for a follow-up seven days after last dose of study drug. Screening is required within 28 days prior to Day 1. This study is for research purposes only and is not intended to treat any medical condition.

NCT ID: NCT03180762 Recruiting - Healthy Clinical Trials

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64140284 in Healthy Participants

Start date: May 30, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the safety and tolerability of JNJ-64140284 versus placebo after single oral dose administration (ascending dose levels) under fasted condition, to characterize the pharmacokinetics (PK) of JNJ-64140284 in plasma, cerebrospinal fluid (CSF) and urine after single oral dose administration and to investigate the effect of food (high fat/high calorie) on the PK of JNJ-64140284 following single oral dose administration.

NCT ID: NCT03175614 Recruiting - Healthy Clinical Trials

Impact of the Usefulness of ICTs on the Increase of Physical Activity and Weight Loss in Obese and Sedentary People.

EVIDENT3
Start date: June 1, 2017
Phase: N/A
Study type: Interventional

This is a randomized clinical trial aimed at obese and sedentary subjects aged 20 to 65 years selected in urban primary care centers of 5 centers (Spain). Its objective is to evaluate the effects of the addition of an ICT tool developed for the Smartphone application and a Smartband in support of behavioral and educational recommendations to reduce weight.

NCT ID: NCT03174613 Recruiting - Healthy Clinical Trials

A Study To Evaluate The Safety, Pharmacokinetics/Pharmacodynamics (PK/PD) and Food Effect Of LC51-0255

Start date: May 31, 2017
Phase: Phase 1
Study type: Interventional

1. To evaluate the safety and tolerability of LC51-0255 in healthy male subjects 2. To evaluate the pharmacokinetic/pharmacodynamics characteristics (PK/PD) of LC51-0255 in healthy male subjects 3. To evaluate bioavailability of LC51-0255

NCT ID: NCT03172910 Recruiting - Healthy Clinical Trials

Study of Ciraparantag Administered to Volunteers Anticoagulated With Rivaroxaban, Measure Clotting Times Using WBCT

Start date: May 8, 2017
Phase: Phase 2
Study type: Interventional

This study is a randomized, single-blind, placebo-controlled study to assess the efficacy and safety of ciraparantag administered to healthy volunteers anticoagulated with rivaroxaban measuring clotting times using Whole Blood Clotting Time (WBCT).

NCT ID: NCT03170531 Recruiting - Healthy Clinical Trials

A Custom-Designed MR Coil for Spine Radiotherapy Treatment Planning

Start date: May 23, 2017
Phase: N/A
Study type: Observational

The purpose of this study is to assess the image quality improvement provided by a custom MR spine coil in comparison with the FDA approved coil when used for radiotherapy treatment planning.

NCT ID: NCT03169088 Recruiting - Healthy Clinical Trials

"Cook to Health Study 2"

C2H2
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Unhealthy lifestyles are major factors contributing to chronic conditions that impose a huge financial burden in EU healthcare systems. Unfortunately, the communication of Public Health failed to influence consumer to change their habits. In this study, the aim is to evaluate the impact of a regular monitoring during 1 year on wellbeing and dietary habits in healthy volunteers. This study follows the pilot study "cook to health" and is intended to confirm the results obtained by the tools used in C2H, in a larger population (25-50 years)

NCT ID: NCT03165162 Recruiting - Healthy Clinical Trials

Assessing Consumer's Characterization of the Term Natural in a Food Context

NTR
Start date: May 22, 2017
Phase: N/A
Study type: Interventional

The purpose of this project is to gain a better understanding of the underlying consumer motivations associated with choosing foods labeled as "natural"; and further, how the use of this term impacts the amount of food consumed.

NCT ID: NCT03163043 Recruiting - Healthy Clinical Trials

Protein Requirements for Active Children

IAAO-C
Start date: October 22, 2016
Phase: N/A
Study type: Interventional

Nutritional requirements for dietary amino acids in children have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity in healthy, active children. The purpose of this study is to measure the protein requirement in children (boys and girls) using the IAAO technique in the presence of a variable intensity exercise stimulus. It is hypothesized that the present study will deem current amino acid requirements to be underestimates of appropriate amino acid requirements for this population.