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NCT ID: NCT03844152 Not yet recruiting - Healthy Clinical Trials

RIGHTWHEY - Responders In Gut HealTh Markers Using Fermented WHEY

RIGHTWHEY
Start date: February 28, 2019
Phase: N/A
Study type: Interventional

This 8-week intervention will investigate the effect of daily consumption of a fermented whey concentrate on the short-chain fatty acid profile of faeces in healthy individuals. This study will help us understand if consumption of fermented foods rich in lactic acid have a beneficial effect on gut health.

NCT ID: NCT03843151 Not yet recruiting - Healthy Clinical Trials

A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1358894 in the Blood

Start date: March 5, 2019
Phase: Phase 1
Study type: Interventional

The main objective of this trial is to investigate the relative bioavailability of BI 1358894 in plasma when given as oral single dose together with multiple oral doses of itraconazole (Test, T) as compared to when given alone as oral single dose (Reference, R).

NCT ID: NCT03842761 Not yet recruiting - Healthy Clinical Trials

A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems

Start date: February 27, 2019
Phase: Phase 1
Study type: Interventional

The primary objective of this trial is the evaluation of safety and tolerability in patients with mild to moderate hepatic impairment [Child-Turcotte-Pugh (CTP) classification A and B] over different dose regimes of BI 685509 compared to placebo. A secondary objective is to investigate pharmacokinetics of different doses of BI 685509 in patients with mild to moderate hepatic impairment (CTP A and CTP B). In addition, another secondary objective is to compare safety, tolerability, and pharmacokinetics in patients with mild to moderate hepatic impairment (CTP A and CTP B) of single BI 685509 dose to individually matched healthy volunteers

NCT ID: NCT03842345 Not yet recruiting - Healthy Clinical Trials

DELPhI Evaluation of Psychiatric Conditions

Start date: February 2019
Phase:
Study type: Observational

DELPhI acquisition and analysis software, a QuantalX Neuroscience development, which is designed to measure, analyze, and display brain electrical activity of human electroencephalogram (EEG), to transcranial magnetic stimulation (TMS), will be used to evaluate different psychiatric conditions.

NCT ID: NCT03841630 Not yet recruiting - Healthy Clinical Trials

A Safety Study of LY3437943 Given as a Single Injection in Healthy Participants

Start date: March 13, 2019
Phase: Phase 1
Study type: Interventional

This study is being conducted to determine the side effects related to LY3437943 given as a single injection under the skin to healthy participants. Blood tests will be performed to check how much LY3437943 gets into the bloodstream and how long the body takes to get rid of it. Each enrolled participant will receive a single dose of LY3437943 or placebo. The study will last up to approximately 71 days for each participant, including screening.

NCT ID: NCT03837964 Not yet recruiting - Healthy Clinical Trials

A Study to Test How Food Influences the Amount of BI 1291583 in the Blood of Healthy Men

Start date: February 28, 2019
Phase: Phase 1
Study type: Interventional

To assess the effect of food on the pharmacokinetics of an oral tablet formulation of BI 1291583, by investigating the relative bioavailability following single dose administration under fed and fasted conditions.

NCT ID: NCT03832452 Not yet recruiting - Healthy Clinical Trials

A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart Function

Start date: February 15, 2019
Phase: Phase 1
Study type: Interventional

Two-part Phase 1 study to assess the effect of single therapeutic and supra-therapeutic doses of lucerastat on the QT/QTc interval duration in healthy subjects (Part A: Pilot study; Part B: TQT study)

NCT ID: NCT03831893 Not yet recruiting - Healthy Clinical Trials

Metabolic Effects of Nopal in Healthy Humans

Start date: February 15, 2019
Phase: N/A
Study type: Interventional

The overall goal is to increase the knowledge that can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people. More specifically the purpose of this study is to evaluate effects on metabolic test markers of Nopal (Opuntia) in healthy humans.

NCT ID: NCT03828084 Not yet recruiting - Healthy Clinical Trials

Randomized, Single-dose, Crossover Study of 4 Decitabine and Tetrahydrouridine (EPI01) Formulations in Healthy Subjects

EPI01
Start date: April 3, 2019
Phase: Phase 1
Study type: Interventional

To study the pharmacokinetic profiles of decitabine and tetrahydrouridine (THU) from 3 modified release formulations in healthy subjects.

NCT ID: NCT03827668 Not yet recruiting - Healthy Clinical Trials

A DRUG-DRUG INTERACTION STUDY BETWEEN PF-06650833 AND PF-06651600 FOLLOWING MULTIPLE DOSES IN HEALTHY PARTICIPANTS

Start date: February 7, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the potential pharmacokinetic (PK) drug-drug interaction (DDI) between PF-06650833 and PF-06651600 in healthy adult participants.