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NCT ID: NCT00847626 Completed - Hypertension Clinical Trials

Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil combined with chlorthalidone, once daily (QD), in participants with moderate to severe hypertension.

NCT ID: NCT00845728 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Exacerbation Study

INVIGORATE
Start date: March 2009
Phase: Phase 3
Study type: Interventional

This study compares indacaterol with tiotropium in terms of bronchodilation over 52 weeks

NCT ID: NCT00839800 Completed - Asthma Clinical Trials

Study to Investigate the Efficacy of Symbicort® SMART.

SAKURA
Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the efficacy of Symbicort SMART (Symbicort Turbuhaler 160/4.5μg, one inhalation twice daily plus as needed) with Symbicort Turbuhaler 160/4.5μg, one inhalation twice daily plus terbutaline Turbuhaler 0.4 mg as needed, as asthma therapy

NCT ID: NCT00839527 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

Start date: February 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of albiglutide in subjects with type 2 diabetes

NCT ID: NCT00839163 Completed - Clinical trials for Deep Vein Thrombosis

Oral Direct Factor Xa Inhibitor BAY59-7939 in Patients With Acute Symptomatic Proximal Deep Vein Thrombosis(ODIXa-DVT)

Start date: March 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of BAY59-7939 with the safety and efficacy of the licensed drug enoxaparin and a licensed oral vitamin K-antagonist and to find the optimal dose of BAY59-7939 for the anticipated phase III trials and for the future clinical use.

NCT ID: NCT00838903 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

Start date: February 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if albiglutide is safe and effective in the treatment of type 2 diabetes.

NCT ID: NCT00831753 Completed - Hepatitis B Clinical Trials

Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Infanrix®Hexa in Healthy Peruvian Infants

Start date: May 2008
Phase: Phase 3
Study type: Interventional

The study aims to confirm that, in Peruvian infants, the investigational DTaP-IPV Hep B-PRP~T vaccine has immunological and safety profiles that are comparable to those of the control vaccine that is already marketed (Infanrix®Hexa) Primary Objective: To demonstrate that the hexavalent DTaP-IPV-Hep B-PRP~T combined vaccine induces an immune response that is at least as good as the response following Infanrix®Hexa in terms of seroprotection rates to HB, one month after a three-dose primary series (2, 4 and 6 months) Secondary Objectives: - To describe in each group the immunogenicity to vaccine components (for DTaP-IPV-Hep B-PRP~T and Infanrix®Hexa) one month after the third dose of the primary series. - To assess the overall safety in each group one month after each dose of the primary series and through the entire study.

NCT ID: NCT00831441 Terminated - Clinical trials for Acute Coronary Syndrome

Phase III Acute Coronary Syndrome

APPRAISE-2
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if apixaban is superior to placebo for preventing cardiovascular death, non-fatal myocardial infarction, or ischemic stroke in subjects with a recent acute coronary syndrome

NCT ID: NCT00826267 Completed - Breast Neoplasms Clinical Trials

6 Weeks Treatment of Locally Advanced Breast Cancer With BIBW 2992 (Afatinib) or Lapatinib or Trastuzumab

Start date: January 2009
Phase: Phase 2
Study type: Interventional

An open-label, randomized three-arm Phase II trial to explore the efficacy of BIBW 2992 as a single agent versus lapatinib versus trastuzumab in patients with HER2-positive treatment-naïve Stage IIIa locally advanced breast cancer. Additional information will be obtained on the safety profile and pharmacokinetics of BIBW 2992.

NCT ID: NCT00820846 Completed - HIV Infections Clinical Trials

Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults

Start date: January 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety of and immune response to a two-vaccine regimen in healthy, HIV-uninfected adults who have never received an HIV preventive vaccine before.