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NCT ID: NCT00253357 Completed - Heart Failure Clinical Trials

PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy

Start date: March 2004
Phase: N/A
Study type: Observational

Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes. Using a medical device like a pacemaker or a defibrillator can help the heart to pump in regular beats. However, not all patients do better with a device. Currently, there is not a way to identify which patients will benefit from the device. The purpose of this study is to determine if using medical tests, Echocardiogram, can help in predicting which patients will improve. The types of patients needed for this study are those who have been diagnosed with moderate or severe heart failure.

NCT ID: NCT00253071 Completed - Bipolar Disorder Clinical Trials

Early Integrated Intervention in Severe Affective Disorders

Start date: December 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether early integrated prophylactic combined medical and psychological outpatient treatment is associated with a better prognosis in patients with severe unipolar and bipolar affective disorders than standard treatment.

NCT ID: NCT00252954 Completed - Pain Clinical Trials

Levetiracetam in Chronic Neuropathic Pain Following Spinal Cord Injury

Start date: November 2005
Phase: Phase 4
Study type: Interventional

Purpose: To evaluate the efficacy and safety of levetiracetam on chronic neuropathic pain after spinal cord injury, and to examine its effect on spasms and evoked pain.

NCT ID: NCT00252733 Completed - Type 1 Diabetes Clinical Trials

Diabetic Retinopathy Candesartan Trials

DIRECT
Start date: June 2001
Phase: Phase 3
Study type: Interventional

The primary objective is to determine whether candesartan, compared to placebo reduces the incidence of diabetic retinopathy in normotensive, normoalbuminuric type 1 diabetic patients without retinopathy. The secondary objective is to determine whether candesartan, compared to placebo, beneficially influences the rate of change in urinary albumin excretion rate (UAER). This study is part of the DIRECT Programme also including secondary prevention studies of diabetic retinopathy in both type 1 and type 2 diabetes. The primary objective for all three pooled studies is to determine whether candesartan, compared to placebo, reduces the incidence of microalbuminuria in type 1 and type 2 diabetic patients.

NCT ID: NCT00252408 Completed - Osteoporosis Clinical Trials

Danish Osteoporosis Prevention Study

Start date: October 1990
Phase: Phase 4
Study type: Interventional

Hypothesis: Use of hormone replacement therapy (HRT) decreases the incidence of fractures in early postmenopausal women. The project was initiated in 1990, and the inclusion ended in 1993. A total of 2,016 early postmenopausal women were divided into two groups: The first group accepted randomisation to HRT or not, and the second group was allowed to choose HRT or not. The study was not blinded. Main measurements were fracture risk over 20 years, changes in bone mineral density over 20 years, and side effects, mainly breast cancer.

NCT ID: NCT00252018 Completed - Hypertension Clinical Trials

The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular Disease

Start date: January 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether a daily intake of dried broccoli sprouts will improve the endothelial function of the participants as measured by Flow mediated dilation (FMD) The dried sprouts are chosen because broccoli sprouts are known as containing large amounts af the glucosinolate glucoraphanin which in vitro and in animal models has been shown to have a positive effect on the endothelium as measured by NO release.

NCT ID: NCT00251979 Completed - Clinical trials for Gastrointestinal Hemorrhage

A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer

Start date: October 2005
Phase: Phase 3
Study type: Interventional

This study is being carried out to see if constant 3 days infusion of Nexium is effective in preventing rebleeding after an endoscopic treatment.

NCT ID: NCT00251927 Completed - Clinical trials for Gastroesophageal Reflux

Esomeprazole (NEXIUM) vs. Surgery

LOTUS
Start date: October 2001
Phase: Phase 3
Study type: Interventional

The study investigates the efficacy of long-term treatment of esomeprazole compared to anti-reflux surgery in the control of gastroesophageal reflux disease by assessing time to treatment failure.

NCT ID: NCT00251914 Completed - Dyspepsia Clinical Trials

Nexium Dyspepsia/AST

Start date: December 2002
Phase: Phase 3
Study type: Interventional

The aim is to evaluate if the resolution of upper abdominal symptoms (pain or burning) during an acid suppressive test trial of esomprazole given daily for 7 days predicts symptoms resolution at the end of a subsequent treatment period of 7 weeks.

NCT ID: NCT00251901 Completed - Chest Pain Clinical Trials

Chest Pain Pilot Study

Start date: May 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy of Nexium® with placebo in relief of acid related pain or discomfort in the chest.