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Gastrointestinal Hemorrhage clinical trials

View clinical trials related to Gastrointestinal Hemorrhage.

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NCT ID: NCT06299007 Completed - Clinical trials for Upper Gastrointestinal Bleeding

Awareness of Iron Status Evaluation in UGIB

AISE
Start date: August 1, 2023
Phase:
Study type: Observational

BACKGROUND: Data on the awareness of the need to evaluate iron status and IDA prevalence in acute UGIB are limited. OBJECTIVES: This study aimed to investigate the rate of evaluation of iron status and prevalence of iron deficiency anemia (IDA) and the associated factors in patients with anemia hospitalized for acute upper gastrointestinal bleeding (UGIB).

NCT ID: NCT06297954 Recruiting - Clinical trials for Upper Gastrointestinal Bleeding

Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding

Start date: March 16, 2023
Phase: Phase 3
Study type: Interventional

A prospective, randomized, double-blind study will be conducted, including all patients with upper gastrointestinal bleeding, defined as vomiting blood or black bowel movements, within 12 hours prior to admission. Patients will be randomized to receive intravenous metoclopramide 20 mg or placebo, a placebo is a look-alike substance that contains no active drug. Then endoscopy will be performed in the following 120 minutes, evaluating endoscopic visualization with the modified Avgerinos scale.

NCT ID: NCT06269588 Recruiting - Endoscopy Clinical Trials

Efficacy and Safety of Nexpowder™ for Non-variceal, Upper Gastrointestinal Bleeding

Start date: February 2024
Phase: N/A
Study type: Interventional

The purpose of this pilot clinical trial is to confirm the efficacy and safety of Nexpowder™ for hemostasis in pilot cohort of patients with NVUGIB in Singapore

NCT ID: NCT06269302 Completed - Clinical trials for Gastrointestinal Hemorrhage

Comparison of the Effect of Warfarin and Direct Oral Anticoagulants

Start date: January 1, 2022
Phase:
Study type: Observational

In this study, it was aimed to compare the frequency of new oral anticoagulants and warfarin usage, and to reveal the rates of recurrent upper gastrointestinal bleeding among patients who applied to our hospital with upper gastrointestinal bleeding

NCT ID: NCT06259292 Recruiting - Clinical trials for GastroIntestinal Bleeding

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

CHORUS
Start date: November 13, 2023
Phase:
Study type: Observational [Patient Registry]

The Comprehensive HHT Outcomes Registry of the United States (CHORUS) is an observational registry of patients diagnosed with Hereditary Hemorrhagic Telangiectasia (HHT). The purpose of this study is to better understand HHT, the symptoms and complications it causes, and the impact the disease has on people's lives. The investigators will collect long-term information about the participant, allowing us to understand how the disease changes over time, and what factors can influence those changes. Ultimately, this should help improve treatments for the disease. Another important goal of the study is to provide a way to contact people to participate in future clinical trials and other research. The registry will be a centralized resource for recruitment for clinical trials. People in the registry will not be obligated to join any of these additional studies, but if interested, can agree to be contacted if they may be eligible for a study. Participants will: - Be asked to provide permission to collect information from their medical records, including things like demographic information, diagnosis information, family history, test results, treatment information, symptoms, complications, lifestyle and other relevant medical information. - Be asked study-related questions by phone or at a clinic visit. - Be asked study-related questions every year after enrollment for up to 10 years or until the study ends. A member of the study team will communicate with participants by phone or at clinic visits to collect information regarding any changes to their health over the previous year/s including new test results, treatment information, symptoms, and complications from HHT.

NCT ID: NCT06254443 Recruiting - Clinical trials for Acute Lower Gastrointestinal Bleeding

Oral PEG vs. Enema in Urgent Colonoscopy for ALGIB

CANDLE
Start date: January 8, 2024
Phase: N/A
Study type: Interventional

The main goal of this study is to assess whether the diagnostic efficacy of enema is non-inferior to that of oral polyethylene glycol (PEG) in acute lower gastrointestinal bleeding (ALGIB) patients requiring urgent colonoscopy. The secondary objectives include: 1) evaluating potential differences between the enema and oral PEG groups in terms of the difficulty and safety of colonoscopy, as well as exacerbation of bleeding; 2) conducting subgroup analyses to compare the effectiveness of the two bowel preparation methods in specific populations, exploring potential candidate groups for different bowel preparation strategies, and promoting individualized diagnosis and treatment for ALGIB.

NCT ID: NCT06214234 Not yet recruiting - Esophageal Varices Clinical Trials

Upper Endoscopy in Cirrhotic Patients With Upper Gastrointestinal Bleeding

Varices
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Liver cirrhosis is a common diffuse and persistent liver disease often accompanied by portal hypertension, liver failure, upper gastrointestinal bleeding (UGIB), and other complications. The incidence rate of liver cirrhosis with UGIB is as high as 30-40%, which is related to the rupture bleeding of gastroesophageal varices (GOV), hepatogenic ulcer, portal hypertensive gastropathy, hepatic gastrointestinal failure, etc

NCT ID: NCT06192355 Recruiting - Clinical trials for Upper Gastrointestinal Bleeding

Single-use Versus Reusable Gastroscopes in Patients With Upper Gastrointestinal Bleeding.

OneScopeII
Start date: March 27, 2023
Phase: N/A
Study type: Interventional

Controlled-randomized trial evaluating single-use versus reusable gastroscopes in patients with upper gastrointestinal bleeding.

NCT ID: NCT06188585 Not yet recruiting - Clinical trials for Acute Gastrointestinal Bleeding

Randomized Trial of UI-EWD vs. Conventional Endoscopic Therapy for Bleeding Ulcers

TREET
Start date: May 2024
Phase: N/A
Study type: Interventional

A prospective, multi-center, noninferiority randomized controlled trial designed to compare the efficacy of UI-EWD (Nexpowder™) hemostatic powder versus conventional endoscopic hemostatic therapy in patients presenting with acute overt gastrointestinal bleeding which is found at endoscopy to be due to a gastric or duodenal ulcer with active bleeding (spurting or oozing) or a non-bleeding visible vessel.

NCT ID: NCT06167837 Recruiting - Upper GI Bleeding Clinical Trials

Metoclopramide for Gastric Visualization in Active Upper GI Bleeding

Start date: October 1, 2023
Phase: Phase 4
Study type: Interventional

This study aim to evaluate the efficacy of metoclopramide for gastric visualization in patients with active UGIB. This is a double-blinded, multicenter RCT. Patients with 'active' UGIB (hematemesis or presence of fresh blood in the nasogastric tube) were enrolled. The eligible patients were randomly assigned in a concealed 1:1 allocation to received either intravenous metoclopramide or placebo before endoscopy. The primary outcome was 'adequate visualization' by objective endoscopic visualized scores(EVS). Secondary outcomes included mean difference in total EVS and EVS at each location , duration of EGD, immediate hemostasis, need for a second look EGD, units of blood transfusion, length of hospital stay and 30-day rebleeding rate.