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NCT ID: NCT04029649 Not yet recruiting - Ulcerative Colitis Clinical Trials

Beta-1,3/1,6-D-Glucan Ganoderma Lucidum on Ulcerative Colitis

Start date: August 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to determine the efficacy and safety of Beta-1,3/1,6-D-Glucan from mycelium extract of Ganoderma lucidum on ulcerative colitis

NCT ID: NCT04034368 Not yet recruiting - HBV Clinical Trials

A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Suboptimal Response (SOR) and Intolerant to Entecavir

Start date: August 2019
Phase: Phase 4
Study type: Interventional

This is a multicenter, single arm, open label, historical control pilot Study to the antiviral efficacy and safety of Suboptimal Responders to Entecavir Switching to TAF Treatment at week 48 (investigate the rates of complete virological response on switching to TAF in patients with Suboptimal response or ETV intolerance to standard ETV= 0.5 mg monotherapy).

NCT ID: NCT04034537 Not yet recruiting - Clinical trials for Coronary Artery Disease

Repository of Phase Signals for Algorithm Development and Testing in CAD in CHINA

CADChina
Start date: August 2019
Phase: N/A
Study type: Interventional

The primary objective of this study is to build a repository of resting cardiac phase space signals from eligible subjects using the Phase Signal Recorder (PSR) prior to coronary angiography for the purposes of machine-learning and testing algorithms developed by Analytics 4 Life. Male and Female subjects will be uniquely and consecutively enrolled into one group to support populating a repository of phase signals.

NCT ID: NCT04035538 Not yet recruiting - Hypertension Clinical Trials

A Clinical Study to Compare the Safety and Pharmacokinetics of CKD-320 and D012

Start date: August 2019
Phase: Phase 1
Study type: Interventional

A clinical study to compare the safety and pharmacokinetics of CKD-320 and D012

NCT ID: NCT04036656 Not yet recruiting - Venous Thrombosis Clinical Trials

Phase I Study of Direct Coagulation Factor Xa Inhibitor SYHA136 Tablets in Chinese Healthy Volunteers

Start date: August 2019
Phase: Phase 1
Study type: Interventional

The trial used single-center, randomized, double-blind, placebo-controlled, single-dose ascending study. The trial planned to enroll fifty-six healthy volunteers. The subjects were allocated to eight dose groups, including 0.5 mg (3+1), 1 mg (3+1), 2.5 mg (6+2), 5 mg (6+2), 10 mg (6+2), 20 mg (6+2), 35 mg(6+2) and 50 mg (6+2). Each dose group was allocated test drugs and placebos according to the proportion of subjects in the brackets mentioned above.

NCT ID: NCT04036825 Not yet recruiting - Malnutrition Clinical Trials

Liquid Nutritional Supplement on Malnutrition Hospitalized Patient

Start date: August 2019
Phase: N/A
Study type: Interventional

The aim of this study is to know the effectivity of liquid nutritional supplementation in malnutrition hospitalized patients

NCT ID: NCT04037488 Not yet recruiting - Prostate Cancer Clinical Trials

Changes in Body Composition With Patients Under Androgen Deprivation Therapy

Start date: August 2019
Phase:
Study type: Observational

This study aimed to evaluate the correlation of change in body composition and oncological outcomes of prostate cancer patients under androgen deprivation therapy(ADT).

NCT ID: NCT04037982 Not yet recruiting - Death Clinical Trials

RCT Study on Safety of LPD and OPD in the Treatment of Periampullary Tumors

Start date: August 2019
Phase: N/A
Study type: Interventional

Pancreaticoduodenectomy (PD) is considered one of the most complex and dangerous procedures in general surgery. This procedure is the preferred surgical procedure for treating tumors around the ampulla. Traditional open pancreaticoduodenectomy (OPD) has brought great surgical trauma to patients while treating diseases. In 1994, Gagner et al first reported laparoscopic pancreaticoduodenectomy (LPD). With the development of laparoscopic techniques, the updating of devices, and the continuous accumulation of laparoscopic gastrointestinal surgery experience, the results of retrospective studies published show that there is no significant difference in safety between LPD and OPD. However, the results of the recently published RCT study show that the mortality associated with LPD complications is five times greater than that of OPD. At present, the security of LPD has been controversial. Therefore we conducted a prospective randomized controlled trial with a primary outcome of perioperative complications, providing evidence-based results for the safe and effective clinical development of LPD.

NCT ID: NCT04045392 Not yet recruiting - Breast Cancer Clinical Trials

Effects of Mediterranean Diet Based Intervention in Breast Cancer Patients

Start date: August 2019
Phase: N/A
Study type: Interventional

The purpose of this randomized clinical trial is to examine the effects of Mediterranean diet based intervention on inflammation and metabolic risk factors in overweight or obese postmenopausal women with breast cancer receiving adjuvant hormone therapy.

NCT ID: NCT04049929 Not yet recruiting - Clinical trials for Advanced Solid Tumor

A Phase I Study of YY-20394 in Patients With Advanced Solid Tumors

Start date: August 2019
Phase: Phase 1
Study type: Interventional

Protocol YY-20394-003 is a phase I single arm, open label study. The primary objective is to assess the safety of YY-20394 in subjects with advanced solid tumor. The secondary objective is to determine the preliminary efficacy and pharmacokinetics (PK).