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Wounds and Injuries clinical trials

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NCT ID: NCT06467838 Active, not recruiting - Surgery Clinical Trials

Airway Approaches of Anesthesiology and Reanimation Physicians in Cervical Neck Trauma Patients in Turkey

Start date: January 1, 2024
Phase:
Study type: Observational

Title: Airway Approaches of Anesthesiology and Reanimation Physicians in Cervical Neck Trauma Patients in Turkey: A Survey Study This study aims to evaluate the knowledge, awareness levels, and equipment adequacy of anesthesiology and reanimation physicians in Turkey regarding airway management in cervical neck trauma patients through a 32-question online survey. The findings will inform targeted improvements in training and resource allocation to enhance clinical outcomes in this patient population.

NCT ID: NCT06460025 Active, not recruiting - Clinical trials for Microbial Colonization

Compare Wound Sampling Methods Efficacy in Microbiology Culture

Start date: October 1, 2022
Phase:
Study type: Observational

Slough was a visible indicator of biofilm, which was the most available specimen from acute and chronic wounds. However, studies believed that slough were poorly accurate, and that the Levine swab was more recommended for sampling bacterial culture. This study aimed to compare slough with swab sample and analyze the consistency.

NCT ID: NCT06439108 Active, not recruiting - Clinical trials for Evaluation of Single Symphyseal Plating in APC III Injuries

Single vs Double Symphyseal Plating in Management of Vertically Unstable Open Book Pelvic Ring Injuries:

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

compare functional, radiological outcomes, implant failure and the incidence of recurrent diastasis of single superior symphyseal plate versus double plating in management of vertically unstable open book injuries

NCT ID: NCT06401655 Active, not recruiting - Stroke Clinical Trials

Financial Coaching for Adults Living With Acquired Brain Injury

Start date: February 21, 2024
Phase: N/A
Study type: Interventional

This pilot study will utilize a longitudinal concurrent mixed-methods research design that gathers and analyzes qualitative and quantitative data overtime about a new 10-session financial coaching program the investigators have developed. The data collected will be used to inform improvements to future related studies and programs for people living with acquired brain injury (ABI). These mixed-methods data from each method will be integrated to provide a comprehensive understanding of the intervention (i.e., the financial coaching program). Each individualized intervention per ABI-survivor participant will be completed over 3-4 months (i.e., 12-14 weeks).

NCT ID: NCT06400082 Active, not recruiting - Wound Complication Clinical Trials

Topical Insulin for Postoperative Wound Healing

Start date: April 16, 2023
Phase: N/A
Study type: Interventional

This study aimed to investigate the potential effect of applying topical insulin therapy on the management and healing of postoperative wounds in patients known with type 2 diabetes mellitus (T2DM) and in a parallel group without diabetes. Investigators also studied the effect of topical insulin therapy on the expression of e-cadherin and Ki67, as markers for cellular proliferation and wound repair. The levels of IL-6 and the H2O2-induced DNA damage product, 8-hydroxy-2'-deoxyguanosine (8-OHdG), were assessed as markers for inflammation and oxidative stress. Finally, histomorphological assessment of skin biopsies was also carried out.

NCT ID: NCT06388980 Active, not recruiting - Nurse's Role Clinical Trials

Knowledge and Needs of Nursing in Relation to the Treatment Complex Wounds

Start date: May 1, 2023
Phase:
Study type: Observational

Study with cross-sectional and descriptive mixed methodology. With questionnaires with likert-type questions (0-10) being the 10 with the highest score, and open questions in relation to knowledge in wound care; include all Corporaciló Sanitària Parc Taulí (CCSPT) nurses who voluntarily want to participate in a pseudo-anonymized surv

NCT ID: NCT06365827 Active, not recruiting - Acute Kidney Injury Clinical Trials

Perioperatively Assessed Biomarker I-FABP Level for Prediction of Acute Mesenteric Ischemia and Its Correlation With Acute Kidney Injury, Followed by Extracorporeal Circulation (aMIKI)

aMIKI
Start date: March 1, 2022
Phase:
Study type: Observational [Patient Registry]

Acute mesenteric ischemia (AMI) is a severe condition that might occur after cardiovascular surgery. Several risk factors for AMI, such as multimorbidity, the use of vasopressors, and an increase in inflammatory markers have been identified in the past. However, these risk factors also seem to influence the blood and urine levels of I-FABP. This prospective pilot study intends to evaluate the value of perioperatively assessed I-FABP levels and to correlate these values with clinical or angiographic findings in mesenteric ischemia to improve a standardised diagnosis.

NCT ID: NCT06356480 Active, not recruiting - Diabetic Wounds Clinical Trials

1% Acetic Acid vs Normal Saline Dressing inManagement of Diabetic Foot

Start date: October 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Chronic diabetic wounds are those wounds that are persistent and do not respond to any sort of treatment. The concept of using topical antiseptics on open wounds is to prevent and treat infections. They also help to shorten the time taken to heal the wounds. The use of topical agents on wounds to prevent infection is a minimal ability to develop resistance to the microorganisms. Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen with innate resistance to many antibiotics. In places that are economically backward, these problems get compounded by the inability of patients to afford newer expensive drugs. Topically applied dilute acetic acid, which is cheap and easily available, has been found to be effective in such chronic diabetic wounds

NCT ID: NCT06333886 Active, not recruiting - Clinical trials for Spinal Cord Injuries

Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury

Start date: March 18, 2024
Phase:
Study type: Observational

Assessing the sacral nerves is an integral aspect of the evaluation after a spinal cord injury. Being located at the lower end of the spinal cord, the sacral nerves reflect how signals travel through the injured spinal cord. Sacral assessment is therefore essential to determine the level and severity of the spinal cord injury, which helps selecting the proper treatment and predicting recovery (worse when abnormal sacral function. The current assessment relies solely on a manual evaluation, which depends heavily on the physician's experience and does not provide any quantitative value of the dysfunction. The lack of a quantitative method adapted to the clinical setting is a major barrier limiting our knowledge on the impact of sacral function on recovery. We have recently developed an electrophysiological method providing quantitative sacral assessment at bedside after spinal cord injuries. Using this method, we will quantify sacral function in 250 patients with acute spinal cord injuries, and determine its association with recovery 6 months post-injury. We hypothesize that sacral function assessed early within the first 6 weeks after the injury with our method is associated with a better 6-month recovery of motor, sensory, bowel and bladder function. Our objectives are to assess the changes is sacral function during the first 6 months after the injury, and the relationship between early sacral function and 6-month recovery. Sacral function and recovery will be assessed up to 6 months post-injury by the attending physician, in order to measure the electromyographic magnitude of voluntary anal contraction, electromyographic magnitude of anal contraction elicited through sacral reflex testing, and minimal electrical stimulation for which anal sensation is present. The analysis will determine if and how sacral function evolves in time, and if there are specific quantitative criteria of sacral function that physicians can use to determine if patient will have a favorable recovery.

NCT ID: NCT06325228 Active, not recruiting - Healthy Clinical Trials

Musculoskeletal Injuries, Sports Performance, Sports Specialization, and Quality of Life in Young Athletes

Start date: February 1, 2023
Phase:
Study type: Observational

The primary aim of this observational cohort study is to assess sports specialization, sports performance, history of injuries (prevalence, types, areas, duration) and quality of life in young healthy athletes aged 8-16 from Poland. Athlete profiles will be created based on the variables (explained in detailed description) examined. Furthermore, the investigators will perform one-year injury follow-up. The main questions it aims to answer are: - Do athletes with a specific profile (lower values in athletic performance tests, low values in quality of life) evaluated at one time point, suffer injury in the future in annual observation? - Do athletes with high sports specialization will sustain injury in one-year follow-up? - Does sports specialization have a relationship with sports performance tests, and quality of life? - Does sport specialisation, training volume, geographical factor relate to injury history? - Does sports specialisation, injury history differ between sports (individual and team sports)? - Does value of the specific muscle (lower limb) isometric strength will be associated with the dynamic balance scores in young healthy athletes?