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Wounds and Injuries clinical trials

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NCT ID: NCT06464250 Completed - Diabetic Foot Ulcer Clinical Trials

The Effect of Bundle Approach on Foot Care Behaviors and Diabetic Wound Healing in Patients

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This study was planned to standardize foot care behaviors with a patient-participated care package approach, to ensure healing of existing wounds, and to evaluate the effect on foot care behaviors to prevent the development of new diabetic foot ulcers. The sample of the study consisted of a total of 97 patients, 49 patients in the care package group and 48 patients in the control group. Hypotheses of the Study H1. The foot care behaviors of patients who receive a patient-participatory care package approach to diabetic foot ulcer prevention will be higher than those of patients who do not receive a care package. H2. Patient-involved care package approach prevents the development of new diabetic foot ulcers. H3. Patient-involved care package approach provides healing of existing diabetic ulcers.

NCT ID: NCT06462755 Completed - Clinical trials for Postoperative Acute Kidney Injury

Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

Start date: January 1, 2009
Phase:
Study type: Observational

To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population. The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation. Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.

NCT ID: NCT06444672 Completed - Clinical trials for Spinal Cord Injury L1- L5

Effects of a Home-Based Rehabilitation on Anthropometric Measures, Sensory-Motor Functions and Independence After Spinal Cord Injury

HBRSCI
Start date: September 25, 2021
Phase: N/A
Study type: Interventional

Background: The scarcity of resources for spinal cord injury (SCI) rehabilitation constitutes a significant obstacle, particularly in war-torn regions experiencing a rise in such injuries. Implementing a home-based rehabilitative program (HBRP) tailored to patients' environmental, social, and financial contexts is crucial in mitigating this challenge. The authors investigated the effects of a 24-month HBRP on anthropometric measurements, muscular strength, sensory and motor function, and independence in participants transitioning from bed to walking following SCI. Methods: Serial case study in a quasi-experimental design, the conducting was at the participants' homes. The participants were four patients with SCI (experimental group) and another two patients with SCI (control group). The interventions were a 24-month HBRP comprising strength, flexibility, and balance training, the outcome measures involved anthropometric measurements, muscle strength using a digital handheld dynamometer, muscle thickness, and cross-sectional area measured using magnetic resonance imaging, measured five walking tests, and the American Spinal Injury Association scale (ASIA) score for assess the sensory and motor score, and the Spinal Cord Independence Measure (SCIM).

NCT ID: NCT06442332 Completed - Injuries Clinical Trials

Long-term Consequences of Cyclist Injuries

RECYCLIST WP4
Start date: June 26, 2023
Phase:
Study type: Observational

There is a lack of knowledge about the extent of bicycle injuries in Norway. Among other things, a significant underreporting of bicycle injuries has been found in the official road traffic accident statistics based on police-registered accidents. Furthermore, there is a lack of knowledge about the long-term consequences of serious bicycle injuries. The main purpose of this project is to generate new knowledge about the consequences of bicycle injuries for later disability, employment status and use of prescribed drugs. In addition, the investigators want to study whether such long-term consequences vary according to demographic and socioeconomic characteristics, as well as to assess the degree of overlap between bicycle injuries registered in the official road traffic accident statistics and bicycle injuries registered in the health service, including an assessment of the severity of the injury. The investigators will use a retrospective analysis where a population-based dataset from the National Population Register is linked with information on injured cyclists from Statistics Norway's database on police-reported road traffic accidents, the Norwegian Patient Register, the National Trauma Registry and the Norwegian Cause of Death Registry. In order to study the long-term consequences of bicycle injuries, the investigators will also compile information on social security benefits and employment from Statistics Norway's historical events database (FD-Trygd) and the use of prescribed drugs from the Norwegian Prescribed Drug Registry. The investigators will also collect information on income and educational attainment from registers in Statistics Norway. The project will contribute to increased knowledge about the societal and individual burden of bicycle injuries, knowledge that is crucial for prioritizing and implementing necessary preventive measures.

NCT ID: NCT06423469 Completed - Clinical trials for Traumatic Brain Injury

Noninvasive Intracranial Pressure Waveforms Assessment in Traumatic Brain Injury

Start date: February 1, 2020
Phase:
Study type: Observational [Patient Registry]

In clinical practice, hospital admission of patients with altered level of consciousness ranging from drowsiness to decreasing response states or coma is extremely common. This clinical condition demands effective investigation and early treatment. Imaging and laboratory tests have played increasingly relevant roles in supporting clinical research. One of the main causes of coma is intracranial hypertension (IH), with traumatic brain injuries (TBI) and cerebral hemorrhages being the major contributors to its development. IH increases the risk of secondary damage in these populations, and consequently, morbidity and mortality. Clinical studies show that adequate intracranial pressure (ICP) control in TBI patients reduces mortality and increases functionality. Unfortunately, the most accurate way to measure and evaluate the ICP is through a catheter located inside the skull, and its perforation is required for this purpose. Several studies have attempted to identify noninvasive solutions for ICP monitoring; however, to date, none of the techniques gathered sufficient evidence to replace invasive monitors. Recently, an extensometer device has been developed, which only maintains contact with the skull's skin and therefore eliminates the need for its perforation, being able to obtain recordings of cranial dilatation at each heartbeat and consequently reflecting brain compliance. In vivo studies have identified excellent qualitative correlation with catheter ICP recordings. However, this device was evaluated only in a limited number of clinical cohorts and the correlations between the information provided by this device with patients outcomes is still poor. Therefore, this project aims primarily to evaluate the use of this noninvasive brain compliance monitoring system in a cohort of TBI patients.

NCT ID: NCT06420856 Completed - Lisfranc Injury Clinical Trials

Changes of Various Structures After Lisfranc Injury Compared to Healthy Individuals.

Start date: January 2, 2024
Phase:
Study type: Observational

The effect of muscular strength deficits on postural control after Lisfranc injury has been explained in relation to stance duration and strength. However, the relationship between protective sole sensation and changes in ankle proprioception, balance, ankle mobility and Achilles tendon structural properties has been shown in previous studies. The aim of our study was to determine the possible changes in protective sole sensation, ankle proprioception, balance and functional capacity after Lisfranc injury and to analyse the relationship between these variables.

NCT ID: NCT06406504 Completed - Pressure Injury Clinical Trials

Improving Pressure Injury Classification and Assessment Skills: In Situ Simulation and Moulage

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effectiveness of in-situ simulation and moulage to improve nursing students' pressure injury classification and assessment skills. A randomized controlled model with a pretest-posttest control group was used in this study. The population of the study consists of a faculty of nursing at a state university. The sample consisted of 84 nursing students. The control group received simulation-based training using a pressure injury simulator on a standardised patient in the simulation laboratory, the in-laboratory simulation group received simulation-based training using moulage on a standardised patient in the simulation laboratory, and the in-situ simulation group received simulation-based training using moulage on a standardised patient in the clinic of a university hospital. The research data were collected by Descriptive Characteristics Form, Pressure Injury Knowledge Test, Pressure Injury Assessment Form, Performance Checklist, Students' Satisfaction and Self-Confidence Scale and Student Feedback Form.

NCT ID: NCT06402669 Completed - Trauma Injury Clinical Trials

Extremity Trauma At a Level 1 Trauma Center

Start date: January 1, 2022
Phase:
Study type: Observational

Blunt vascular trauma to the lower extremity has been associated with injuries to the anteroposterior tibial arteries or popliteal artery in the form of transection, occlusion, or intimal injury. With many blunt injuries resulting in orthopedic fractures, the incidence of limb loss increases substantial. Distal vascular injuries combined with complex orthopedic fractures are more likely to result in limb loss. A recent retrospective study showed two main predicative factors resulting in limb loss was a result of multi-segmental bone fractures and prolong ischemic time greater then 10 hours.

NCT ID: NCT06399913 Completed - Computed Tomography Clinical Trials

Cerebral Computed Tomography on Patients With Minor Head Injuries

Start date: January 1, 2023
Phase:
Study type: Observational

This observational study aims to calculate the prevalence of conditions or diseases requiring immediate medical attention in CTC scans with an indication of bleeding post trauma performed in the ED at Odense University Hospital. Secondary, we aim to evaluate the Scandinavian Neurotrauma Committee clinical guideline 2013 for minor head injury.

NCT ID: NCT06379516 Completed - Clinical trials for Validation of the Process of Wound Creation and Evaluation

Process Validation in Dermatology: Assessing Wound Creation Methods and Treatment Efficacy

Start date: January 17, 2024
Phase: N/A
Study type: Interventional

The primary objective of this study is to validate controlled methods of wound, including 1%w/v SLS, 3%w/v SLS, and 24-24 times tape stripping, on the forearms of subjects. The study aims to standardize the procedures for creating wounds and systematically evaluate the effects of these methods on various skin parameters.