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Wounds and Injuries clinical trials

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NCT ID: NCT06379919 Recruiting - Wound Irrigation Clinical Trials

Wound Irrigation Comparative Effectiveness Study

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline Irrigation (Group 1) or Irrisept Irrigation (Group 2). Secondary objectives are evaluation of patient reported outcome measures and range of motion in relation to C acnes presence among subjects in the two groups.

NCT ID: NCT06379711 Not yet recruiting - Clinical trials for Cardiovascular Diseases

Cardiopulmonary Changes Following Spinal Cord Stimulation in Individuals With Spinal Cord Injury

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to examine the mechanisms of transcutaneous spinal cord stimulation (tSCS) for improving cardiovascular and pulmonary function in individuals with chronic motor-complete spinal cord injury (SCI) by measuring vascular related endothelial biomarkers, plasma catecholamines, and respiratory parameters.

NCT ID: NCT06379672 Not yet recruiting - Long COVID Clinical Trials

Resonance Breathing Training for Long Covid-related Myocardial Injury

Start date: May 25, 2024
Phase: N/A
Study type: Interventional

An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury

NCT ID: NCT06379516 Completed - Clinical trials for Validation of the Process of Wound Creation and Evaluation

Process Validation in Dermatology: Assessing Wound Creation Methods and Treatment Efficacy

Start date: January 17, 2024
Phase: N/A
Study type: Interventional

The primary objective of this study is to validate controlled methods of wound, including 1%w/v SLS, 3%w/v SLS, and 24-24 times tape stripping, on the forearms of subjects. The study aims to standardize the procedures for creating wounds and systematically evaluate the effects of these methods on various skin parameters.

NCT ID: NCT06375980 Completed - Lung Injury Clinical Trials

Intraoperative Mechanical Power and Ventilation-Associated Lung Injury: Assessing Complications

Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

This study investigates the relationship between intraoperative mechanical power and postoperative pulmonary complications in patients undergoing major abdominal surgery. We record mechanical ventilation parameters and surgical characteristics, assessing the incidence of pulmonary complications within 24 hours postoperatively

NCT ID: NCT06375421 Enrolling by invitation - Clinical trials for Traumatic Brain Injury

Pilot and Feasibility of MEMI for Chronic Traumatic Brain Injury

Start date: April 3, 2024
Phase: N/A
Study type: Interventional

This is a pilot and feasibility study for a mobile phone-delivered intervention for memory, called MEMI (memory ecological momentary intervention), that was designed to support adults with chronic traumatic brain injury with their memory. The goal of the study is to examine the feasibility and acceptability of MEMI and to assess preliminary efficacy as to whether technology-delivered spaced memory retrieval opportunities improve memory in people with and without a history of chronic traumatic brain injury.

NCT ID: NCT06374225 Not yet recruiting - Critical Illness Clinical Trials

Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention

SAVE-O2 AI
Start date: April 2024
Phase: N/A
Study type: Interventional

This study is a multicenter randomized controlled trial to determine the effectiveness of a closed loop/autonomous oxygen titration system (O2matic PRO100) to maintain normoxemia (goal range SpO2 90-96%, target 93%) during the first 72 hours of acute injury or illness, compared to standard provider-driven methods (manual titration with SpO2 target of 90-96%).

NCT ID: NCT06373900 Completed - Wound Heal Clinical Trials

Wound Closure After Total Knee Arthroplasty: Comparison of Polypropylene and Polyglactin 910 Suture.

Start date: February 13, 2022
Phase: N/A
Study type: Interventional

Comparison of wound complication and scar formation in patient undergone bilateral total knee replacement comparison between polypropylene and polyglactin 910 suture. patient randomised according to SNOS protocol into group A and B for their right and left knee closure with each suture. patient followed on 3rd, 7th, 15th and 30th post operative day for wound healing, wound dehiscence and scar formation.

NCT ID: NCT06372444 Not yet recruiting - Sepsis Clinical Trials

Mechanisms of Acute Kidney Injury in Severe Infections

PET-AKI
Start date: May 1, 2024
Phase:
Study type: Observational

Renal perfusion and neutrophil-mediated inflammation will be assessed in the kidney in sepsis patients with acute kidney injury using positron emission tomography. For marked water will be used for renal perfusion and a newly developed PET tracer molecule (11C-GW457427) with specific binding to neutrophil elastase which provides a measure of the amount of infiltrating neutrophils in the renal parenchyma for inflammation. The study is performed in a PET-CT camera where anatomical imaging takes place at the same time as the PET examinations.

NCT ID: NCT06371430 Recruiting - Wounds and Injuries Clinical Trials

Bone Bioactive Liquid Efficiency in Improving Dental Implant Osteointegration Oral Soft Tissue Hellingand Oral Surgery

BBLIS
Start date: April 14, 2021
Phase: N/A
Study type: Interventional

The investigators implanted 264 Galaxy TS implants (with or without BBL) in 33 patients across both jaws. Implant stability and osseointegration were assessed using Initial Stability Quotient (ISQ) measurements, computed tomography (CBCT) scans and pain evaluations at various intervals post-surgery. Further, implant surfaces were examined using scanning electron microscopy (SEM) and atomic force microscopy (AFM). In vitro studies evaluated the efficacy of BBL on dental pulp pluripotent stem cells (DPPSCs) osteogenesis, and inflammatory factor modulation in human macrophages.