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Wounds and Injuries clinical trials

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NCT ID: NCT05424354 Active, not recruiting - Wounds and Injuries Clinical Trials

Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing

Start date: May 26, 2022
Phase: Phase 4
Study type: Interventional

This study is being performed to assess the effectiveness of Altrazeal(R) Transforming Powder Dressing (TPD) in patients with partial thickness burns compared to the current standard of care (SOC) dressing. Adult men and women 18-65 years old who are hospitalized with an acute (meaning the burn injury occurred less than 36 hours prior to enrollment in the study) partial thickness burn wound, less than 20 percent of total body surface area may be considered. Subjects will be randomized in a 1:1 ratio to either SOC or TPD. Subjects will be followed for up to 28 days after enrollment.

NCT ID: NCT05400551 Active, not recruiting - Concussion, Brain Clinical Trials

Craneofacial Injuries in Rink Hockey Athletes

Start date: September 1, 2022
Phase:
Study type: Observational

To collect the number of injuries that affect the face and head in rink hockey athletes prospectively during a regular season.

NCT ID: NCT05376449 Active, not recruiting - Clinical trials for Spinal Cord Injuries

Spinal Cord Injury - Exercise

Start date: May 9, 2022
Phase: N/A
Study type: Interventional

Long lasting inflammation in the body is related to cardiovascular and respiratory disease, which are the two most common causes of death in people living with spinal cord injury (SCI). Individuals with SCI have been reported to have higher levels of inflammation when compared to healthy individuals. Exercise is a well-known method to reduce inflammation; however, people with SCI are often inactive. The main goal of this study is to determine whether a 12-week adaptive exercise program can reduce inflammation in people with SCI. Participants will be randomized to start exercise immediately or after a 12-week delay.

NCT ID: NCT05363683 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Optimizing Movement After ACL Injury

Start date: November 11, 2021
Phase: N/A
Study type: Interventional

This study will evaluate if a visual biofeedback program leads to improved knee outcomes after anterior cruciate ligament reconstruction. Outcome measures will include biomechanical movement patterns and markers of knee osteoarthritis on magnetic resonance imaging.

NCT ID: NCT05360524 Active, not recruiting - Clinical trials for Cervical Spinal Cord Injury

Laminectomy Alone Versus Laminectomy and Fusion for Traumatic Cervical Spinal Cord Injury Without Instability

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The aim of study is to compare clinical and radiological outcomes of laminectomy alone to laminectomy and fusion in the treatment of traumatic cervical spinal cord injury without instability.

NCT ID: NCT05341427 Active, not recruiting - Burn Wound Clinical Trials

DEVELOPMENT OF A CLINICAL PREDICTION RULES TO IDENTIFY EFFICACY OF PULSED ELECTROMAGNETIC THERAPY ON BURN WOUND HEALING

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether patients' age, total burned surface area, wound stage and wound depth determine wound healing response to pulsed electromagnetic therapy in burn patients

NCT ID: NCT05328986 Active, not recruiting - COVID-19 Clinical Trials

Kidney Disease After COVID-19

Start date: January 4, 2020
Phase:
Study type: Observational [Patient Registry]

To understand the long-term epidemiology, develop effective risk-prediction and stratification tools, and understand the pathobiology of kidney disease in COVID-19 survivors.

NCT ID: NCT05320445 Active, not recruiting - Clinical trials for Musculoskeletal Injury

A Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Trauma

Start date: January 23, 2023
Phase: N/A
Study type: Interventional

Traumatic physical injuries result in significant disability and a high proportion of survivors suffer from chronic pain and mental health disorders. A key predictor of good outcomes following trauma is "coping self-efficacy" - a person's belief that they can cope with life's challenges. Interventions that enhance coping self-efficacy post-injury are most likely to optimize recovery. However, these interventions are not standard approaches in rehabilitation settings.Our inter-disciplinary team will undertake a trial to assess the efficacy of supportive-expressive group therapy in rehabilitation inpatients who have had traumatic injuries. We wish to test whether persons who undergo the group therapy have significant improvements in coping self-efficacy compared to those receiving standard care. Sixty patients with traumatic injuries admitted to St. John's Rehab will be randomized to either supportive-expressive group therapy (n=30) or to standard rehabilitation (n=30). Additionally, up to 12 staff participants will be recruited.The goal of this project is to establish a gold standard for inpatient rehabilitation in the trauma NMSK injured population by widening the access to emotional wellbeing supports, which could translate into better physical, mental and social health in the community.

NCT ID: NCT05295108 Active, not recruiting - Clinical trials for Spinal Cord Injuries and Disorders (SCI/D)

Caring Connections: A Program to Alleviate Social Isolation and Loneliness in Individuals Living With Spinal Cord Injury

Start date: June 22, 2023
Phase: N/A
Study type: Interventional

This study will use a randomized controlled design with an active attention control group to evaluate an intervention intended to reduce social isolation and loneliness in persons with SCI/D. The intervention, Caring Connections, is a peer-based intervention which is important because peers with SCI/D play an important role in improving quality of life, mental health, and social health in persons with SCI/D.

NCT ID: NCT05294237 Active, not recruiting - Athletic Injuries Clinical Trials

Injury Prevention in Danish Youth Handball

Start date: June 21, 2021
Phase: N/A
Study type: Interventional

The primary aim of this hybrid-effectiveness-implementation cluster randomised study is to investigate if a supported implementation of an injury prevention exercise program (Happy program) involving a train-the-trainer workshop and coach support during the season is superior to an unsupported implementation of the Happy program involving the availability of the program on webpages, in improving adherence (volume, frequency, duration) of the Happy program among coaches for young (11-17 years of age) Danish female and male handball players during one handball season. Secondary aims are to investigate if the supported implementation is superior to the unsupported implementation in improving behavioural outcomes among the coaches and in reducing the risk for new ankle, knee, and shoulder injuries among young (11-17 years of age) Danish female and male handball players during one handball season. Further, the investigators aim to evaluate how and why adherence and behavioural determinants towards use of the Happy program might improve (or not).