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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT05086939 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Multicenter Clinical Trial Comparing Treatment With Allogeneic Mesenchymal Cells Versus Autologous Mesenchymal Cells and Versus Active Control With Hyaluronic Acid in Patients With Knee Osteoarthritis (ARTROCELL)

ARTROCELL
Start date: May 26, 2021
Phase: Phase 3
Study type: Interventional

Phase III, multicenter, randomized, open-label, multicenter clinical trial comparing treatment with allogeneic mesenchymal cells versus autologous mesenchymal cells and versus active control with hyaluronic acid in patients with knee osteoarthritis.

NCT ID: NCT05084014 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Effects of Deep Stripping Versus Kneading on Pain, Range of Motion and Function in Knee Osteoarthritis

Start date: February 11, 2021
Phase: N/A
Study type: Interventional

This is a randomized controlled trial, 44 participants selected based on inclusion criteria from physical therapy department of Surriya Azeem Surgical Hospital, Pattoki. Participants randomly recruited into two groups, 22 in deep stripping group receiving deep stripping with conventional physical therapy and 22 in kneading group receiving kneading with conventional physical therapy. Pain, range of motion and functional mobility are the primary outcomes measured by numeric pain rating scale, universal goniometer and lower extremity functional scale. Data collected at the baseline, at the 6th session, and the 12th session.

NCT ID: NCT05080075 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Platelet Rich Plasma in Knee Osteoarthritis

Start date: November 2021
Phase: Early Phase 1
Study type: Interventional

In this study, the investigators will be performing intra-articular platelet rich plasma (PRP) injections for patients experiencing pain related to osteoarthritis of the knee. The investigators will be following clinical outcomes, and how they relate to concentrations of the PRP samples as well as following opioid and emergency room utilization pre and post-injection.

NCT ID: NCT05079035 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA

Start date: October 2021
Phase: Phase 2
Study type: Interventional

It is hypothesized that a single Intra-articular Injection of TTAX03, 100mg in 2mL of saline, will have more benefit with respect to the proportion of responders 12 weeks post-injection than an equal volume of saline, based on the OMERACT-OARSI responder criteria.

NCT ID: NCT05076539 Recruiting - Knee Osteoarthritis Clinical Trials

A Quantitative Assessment of Early Mobility in Total Knee Replacement Patients Using Smart Activity Tracker

Geospatial
Start date: June 11, 2018
Phase: N/A
Study type: Interventional

This study aims to evaluate the patients' mobility and quality of life prior to their total knee replacement surgery and their progress pre-operatively and 6 months post-operatively using the smart activity tracker. We hypothesize that mobility limitation presents a strong correlation with reduced quality of life.

NCT ID: NCT05062499 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The Effects of Home Use of Transcutaneous Electrical Nerve Stimulation on People With Knee OA and or Chronic Knee Pain

Start date: September 2021
Phase: N/A
Study type: Interventional

The purpose of the research is to see if the use of transcutaneous electrical nerve stimulation (TENS) at home would reduce knee pain and swelling in people with knee OA and/or chronic knee pain.

NCT ID: NCT05058235 Completed - Knee Osteoarthritis Clinical Trials

Comparison of Active Release Technique and Bent Leg Raise In Osteoarthritis.

Start date: November 14, 2020
Phase: N/A
Study type: Interventional

The objective of the study was to compare the effects of active release technique and bent leg raise on hamstring flexibility, functional outcomes, and pain in patients with knee osteoarthritis.

NCT ID: NCT05057559 Recruiting - Knee Osteoarthritis Clinical Trials

Observational Clinical Investigation of Arthrosamid in Knee Osteoarthritis

LUNA
Start date: April 21, 2021
Phase:
Study type: Observational

This is a prospective, long-term, observational, all-comers, open-label, multi-centre clinical investigation enrolling subjects with knee osteoarthritis who is eligible for treatment with Arthrosamid® according to the Instruction for Use.

NCT ID: NCT05054686 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

The Effect of Exercise Combination on Pain, Function and Proprioception in Knee Osteoarthritis

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study will include 3 different groups of intervention. First group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30 minutes walking will be given in seperate days as home program, Second group of knee osteoarthritis patients will be applied both stretching and 30 minutes bicycle exercises in the same session, strengthening exercises and 30 minutes walking will be given in seperate days as home program.Third group of knee osteoarthritis patients will be applied all stretching, strengthening and 30 minutes bicycle exercises in the same session, only 30 minutes walking will be given as home program. The primary outcome measures include the pain, function and the secondary outcome measures include the joint proprioception. The aim of this study is to investigate the effects on outcome measures increasing number of exercises in one session and to determine which exercise types are more suitable to prescribe as a home program.

NCT ID: NCT05050448 Recruiting - Knee Osteoarthritis Clinical Trials

Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain

Start date: August 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the usability of the ultrasound devices and common pain relief gel. The ability of the three treatment approaches to reduce pain, stiffness, and functionality as measured by NRS scale and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) will be evaluated.