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Wounds and Injuries clinical trials

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NCT ID: NCT04954768 Not yet recruiting - Trauma Injury Clinical Trials

Epidemiological Characteristics of Elderly Trauma Patients in Zhejiang Province and Development of Geriatric Trauma Short-term Mortality Prediction Model

Start date: November 2021
Phase:
Study type: Observational

This is a retrospective study. Trauma patients aged 65 years or older will be included. The aims of this study are explore the epidemiological characteristics of elderly trauma patients in Zhejiang Province; establishment of early warning score system of elderly trauma death in Zhejiang Province; and horizontal comparison of the treatment level of elderly trauma in Zhejiang Province.

NCT ID: NCT04953572 Not yet recruiting - Cartilage Injury Clinical Trials

Treatment of Cartilage Defects With Peripheral Blood Stem Cells

Start date: August 1, 2021
Phase: Phase 1
Study type: Interventional

Knee joint cartilage cells metabolize slowly, and it is difficult to repair themselves after injury. Any knee joint trauma or the progression of osteoarthritis may lead to the progression of cartilage or osteochondral defects. Compared with bone marrow mesenchymal stem cells (MSCs), peripheral blood MSCs have better chondrogenic differentiation ability. At the same time, the mobilization of peripheral blood MSCs and the advancement of extraction technology also make it feasible to treat osteochondral damage by using peripheral blood MSCs. The purpose of this study is to evaluate the therapeutic effect of surgical transplantation of autologous peripheral blood MSCs to repair knee joint Ⅳ-degree localized cartilage injury, and to explore a new treatment for osteochondral defects based on the foundation of the research group's previous research.

NCT ID: NCT04953364 Not yet recruiting - Amputation Clinical Trials

Self-Management for Amputee Rehabilitation Using Technology.

SMART
Start date: August 15, 2022
Phase: N/A
Study type: Interventional

Lower Limb Amputations (LLAs) are a substantial burden on the Canadian health services with nearly 50,000 cases reported between 2006 and 2011. To address the challenging nature of a LLA (e.g., decreased mobility, pain, depression), patients need to go through extensive rehabilitation programs. Effective self-management programs can help those with LLA to monitor their own condition and improve their quality of life. However, a lack of self-management programs, a limited healthcare budget, and a decrease in quality of services (e.g. shorter lengths of stay for inpatients and rapid movement to outpatient services) pose further challenges for patients with LLA. Self-management programs can be provided to clients through online mobile technologies (e.g., tablet) and offer accessible, low-cost, and potentially augmentative rehabilitation after discharge, in both urban and rural areas. To address these needs, an online educational and training platform for individuals with LLA called, Self-Management for Amputee Rehabilitation using Technology (SMART) was designed and developed. SMART focuses on LLA education, prosthetic limb management, and weekly support of peers. It is monitored by a trainer through a website. SMART will be evaluated in men and women with LLA aged 50 years and over, admitted to prosthetic rehabilitation throughout BC and ON. SMART has the potential to influence a client's post-LLA needs with direct (e.g., individual's health) and indirect (e.g., healthcare utilization) benefits. The purpose of this randomized controlled trial is to evaluate the effect of SMART in community dwelling older adults with unilateral, above or below, knee amputation.

NCT ID: NCT04953026 Not yet recruiting - Clinical trials for Superior Labrum From Anterior to Posterior Injuries

SLAP Injury of the Shoulder Joint: Application Value of Deep Learning in Diagnosis

Start date: October 1, 2021
Phase:
Study type: Observational

This study intends to study the shoulder SLAP injury through deep learning technology and establish a deep learning model through the combination of axial and oblique coronal images to establish a deep learning method that can accurately identify and grade shoulder SLAP injury.

NCT ID: NCT04946747 Not yet recruiting - Concussion Clinical Trials

Detection and Prevention of Concussive Injuries With Smart Technology.

Start date: June 2021
Phase: N/A
Study type: Interventional

Concussions are consequences of inopportune interactions between an impact force and the head that causes the head (and brain) to move too rapidly. This project involves two parts. 1. The outcome of head-impact depends upon the force and the biomechanical properties of the head-and-neck. Modern microelectrical mechanical systems (MEMS) head-impact sensors only measure the physical parameters of external forces. The researchers have developed a next-generation smart MEMS sensor fortified with artificial intelligence (AI) that can help define a personalized concussive threshold. The researchers sensor machine-learns the biomechanical properties of the participant's head-and-neck and accurately determines the likelihood for concussive injuries. The researchers first goal is to field-test the sensor in soccer players. 2. Researchers hypothesize that an increase in neck stiffness should reduce concussive risks. The researchers have developed a training protocol that involves a conditioned response (CR) to increase neck stiffness during a head-impact event and thereby decrease concussion risk. The Researchers have also developed technology to monitor neck stiffness. The smart sensor is fully integrated into the training protocol and monitors the neck stiffness to validate the effectiveness of the training. The second goal is to optimize and finalize our training protocol and conduct a field-test in soccer players.

NCT ID: NCT04944355 Not yet recruiting - Clinical trials for Urinary Tract Injuries During Caesarean Section for Morbidly Adherent Placenta: Prospective and Retrospective Study

Urinary Tract Injuries During Caesarean Section for Morbidly Adherent Placenta: Prospective and Retrospective Study

Start date: June 2021
Phase:
Study type: Observational

M1- evaluates the cases of lower urinary tract injuries during caesarean section with or without hysterectomy in cases with morbid placental adherence in the period between years 2018 and 2021. This study was carried out in assiut university women health hospital M 2- Clarification of the risk factors and outcome of urinary tract injuries.

NCT ID: NCT04940494 Not yet recruiting - Anal Incontinence Clinical Trials

Anal Incontinence After Obstetrical Anal Sphincter Injury

INCONT-LOSA
Start date: June 24, 2021
Phase:
Study type: Observational

Obstetrical Anal Sphincter Injury is an identified risk factor for anal incontinence. The mechanisms and the risk factors for anal incontinence in Obstetrical Anal Sphincter Injury women are not well known. Anal incontinence in such women is not well documented and probably underestimated. Cohort studies estimated that up to 53% of Obstetrical Anal Sphincter Injury women are incontinent but that most of them does not complain their doctor.

NCT ID: NCT04921592 Not yet recruiting - Clinical trials for Spinal Cord Injuries

Upper Extremity Training for Chronic Cervical Spinal Cord Injury

Start date: June 14, 2021
Phase: N/A
Study type: Interventional

This study is to understand how the combination of activity-based recovery training and targeted spinal cord transcutaneous stimulation (scTS) can improve participants' ability to use their hand, arms, and core.

NCT ID: NCT04917198 Not yet recruiting - Trauma Chest Clinical Trials

Median Sternotomy in Penetrating Cardiac Trauma

Start date: December 21, 2021
Phase: N/A
Study type: Interventional

The investigators aim to assess role of median sternotomy in penetrating cardiac trauma regarding morbidity and mortality of the patients.

NCT ID: NCT04899466 Not yet recruiting - Dehiscence Wound Clinical Trials

Efficacy Evaluation of ActiGraft in Secondary Closure of Abdominal Surgical Wound Dehiscence

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

This is a prospective, single arm study, consisting of 20 women with abdominal surgical wound dehiscence that requires secondary closure. The participants will receive a weekly application of ActiGraft for 4 weeks, or until complete healing of the wound (the earlier of the two). An historic matched-control group of 20 patients will be compared retrospectively