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Ischemic Stroke clinical trials

View clinical trials related to Ischemic Stroke.

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NCT ID: NCT06375174 Active, not recruiting - Clinical trials for Posterior Circulation Acute Ischemic Stroke Due to Large Vessel Occlusion of the Vertebral or Basilar Artery Needing Endovascular Thrombectomy

PRECISE (PERFUSION IMAGING TO IDENTIFY POSTERIOR CIRCULATION CANDIDATES FOR THROMBECTOMY)

SWISS-PRECISE
Start date: January 9, 2024
Phase:
Study type: Observational

We hypothesize that patients with a favorable Critical Area Perfusion Score (CAPS≤3) on cerebral perfusion imaging will have a favorable response to revascularization by thrombectomy and that patients with a CAPS>3 will not

NCT ID: NCT06344312 Active, not recruiting - Clinical trials for Stroke, Acute Ischemic

Effectiveness of Yangxue Qingnao Granules in Preventing Post Thrombolytic Hemorrhage Transformation in Patients With Acute Cerebral Infarction

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Evaluate the effectiveness of Yangxue Qingnao Granules in preventing post thrombolytic hemorrhage transformation in patients with acute cerebral infarction, and explore its possible mechanism

NCT ID: NCT06315153 Active, not recruiting - Ischemic Stroke Clinical Trials

Comprehensive Assessment of Atherosclerotic Ischemic Stroke Risk and Development of a Prediction Model

CAIS-pre
Start date: January 3, 2022
Phase:
Study type: Observational [Patient Registry]

This observational study was designed for the assessment of plaque vulnerability in patients with carotid atherosclerotic stenosis and the development of predictive models for the occurrence and recurrence of atherosclerotic ischemic stroke. The objectives of the study were as follows: first, to integrate the degree of carotid stenosis and plaque characteristics assessed by vascular ultrasound for a comprehensive assessment of plaque vulnerability; second, to develop an assessment tool for the risk of future ischemic stroke in patients with asymptomatic carotid stenosis by combining vascular risk factors, serologic markers, carotid ultrasound characteristics, and contrast-enhanced ultrasonographic parameters; and third, to incorporate vascular ultrasound parameters into existing predictive models of ischemic stroke recurrence risk to develop a risk assessment tool for atherosclerotic ischemic stroke. The main questions it aims to answer are: - How to screen high-risk patients and those eligible for revascularization from asymptomatic carotid stenosis patients for primary prevention of stroke. - How to improve the prediction accuracy of atherosclerotic ischemic stroke based on existing prediction models for secondary prevention of stroke.

NCT ID: NCT06265753 Active, not recruiting - Stroke Clinical Trials

Gastrocinemius Function Massage on Lower Extemity Spasticity

Spasticity
Start date: January 23, 2024
Phase: N/A
Study type: Interventional

This study aimed to investigate gastrocinemius function massage on physical parameters of stroke patients.

NCT ID: NCT06183567 Active, not recruiting - Anesthesia Clinical Trials

The Effect of Sedoanalgesia and General Anaesthesia on Early Neurological Recovery in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The hypothesis of this study is that sedoanalgesia will provide better early neurological recovery than general anaesthesia in acute ischaemic stroke patients undergoing endovascular thrombectomy and to investigate the haemodynamic data of both anaesthetic methods.

NCT ID: NCT06172387 Active, not recruiting - Clinical trials for Acute Ischemic Stroke

Intra-arterial Albumin in Acute Ischemic Stroke After Endovascular Treatment for

Start date: November 1, 2023
Phase: Phase 1
Study type: Interventional

Stroke is an acute focal injury of the central nervous system caused by cerebral vessels. One in every four people is affected by stroke at different times in life. Globally, stroke is the second leading cause of death and third leading cause of disability in adults. we hypothesized that in patients with acute large vessel occlusive ischemic stroke treated with mechanical thrombectomy, the infusion of 20% human serum albumin solution into the revascularization area can exert a stronger neuroprotective effect.

NCT ID: NCT06170086 Active, not recruiting - Stroke, Acute Clinical Trials

Early Neurological Trajectory and Clinical Outcomes in Brain Acute Ischemic Stroke

Start date: September 1, 2023
Phase:
Study type: Observational

Prospective identification of potential responsible blood vessels, provision of intervention targets, prevention of fatal and disabling cerebrovascular diseases, identification of early END patients, determination of clinical treatment pathways, improvement of efficacy, and improvement of prognosis

NCT ID: NCT06121219 Active, not recruiting - Stroke, Ischemic Clinical Trials

Effect of Visual Retraining After Stroke

urochester
Start date: May 7, 2024
Phase: N/A
Study type: Interventional

This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and brain function. The investigators will also assess the effect of intensive visual retraining on the residual visual system, processing of visual information and the use of such information in real-world situations following damage. This research is intended to improve our understanding of the consequences of permanent visual system damage in humans, of methods that can be used to reverse visual loss, and of brain mechanisms by which visual recovery is achieved.

NCT ID: NCT06071091 Active, not recruiting - Clinical trials for Acute Ischemic Stroke

Permanent Intracranial Stenting for Acute Ischemic Stroke Related to a Refractory Large Vessel Occlusion

PISTAR
Start date: November 8, 2023
Phase: N/A
Study type: Interventional

Clot extraction failure during mechanical thrombectomy is a major concern in the management of acute ischemic stroke related to large vessel occlusions. Indeed, it can occur in up to 10 to 30% of cases and, therefore, is associated with a very poor prognosis. These refractory occlusions frequently occur when an underlying intracranial atherosclerotic disease is present. Thus, one of the most promising rescue technique consists of placing a permanent intracranial stent, under dual antiplatelet therapy over the target refractory occlusion. This strategy is well studied in coronary occlusions where the atheroscotic mechanism is highly prevalent. However, as the ischemiated brain is at much higher risk of hemorrhagic complications, such strategy entails a greater risk. This raises the question of whether such risk is worth the reward of obtaining reperfusion. The investigators designed this randomized study in order to evaluate whether a strategy combining rescue pemanent intracranial stenting with the best medical treatment is superior to the best medical treatment alone in acute refractory large vessel occlusions.

NCT ID: NCT06018545 Active, not recruiting - Clinical trials for Acute Ischemic Stroke

AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation

AI-REACT
Start date: June 1, 2023
Phase:
Study type: Observational

This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838). The purpose of the study is to assess the impact of an Artificial Intelligence (AI) tool called qER 2.0 EU on the performance of readers, including general radiologists, emergency medicine clinicians, and radiographers, in interpreting non-contrast CT head scans. The study aims to evaluate the changes in accuracy, review time, and diagnostic confidence when using the AI tool. It also seeks to provide evidence on the diagnostic performance of the AI tool and its potential to improve efficiency and patient care in the context of the National Health Service (NHS). The study will use a dataset of 150 CT head scans, including both control cases and abnormal cases with specific abnormalities. The results of this study will inform larger follow-up studies in real-life Emergency Department (ED) settings.