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Anesthesia clinical trials

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NCT ID: NCT06330038 Not yet recruiting - Clinical trials for Non-small Cell Lung Cancer

Anesthesia and Non-small Cell Lung Cancer Recurrence

GASTIVA
Start date: May 1, 2024
Phase: Phase 4
Study type: Interventional

There has been ongoing debate about the relationship between cancer recurrence and anesthetic management. Therefore, we will test the hypothesis that the recurrence free survival (RFS) after curative resection of NSCLC is higher in patient who received total intravenous anesthesia (TIVA) than volatile anesthetics in this multi-center randomized trials.

NCT ID: NCT06326983 Not yet recruiting - Pain Clinical Trials

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondary measures include rescue opioids administered in post-anesthesia care unit (PACU), re-operation secondary to bleeding, emergence delirium, post-operative nausea and vomiting, intraoperative hemodynamics, intraoperative vasopressor administration, and length of procedure.

NCT ID: NCT06323616 Recruiting - Anesthesia Clinical Trials

The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics

Start date: March 25, 2024
Phase: N/A
Study type: Interventional

Some changes in the patient's cognitive state are observed during the recovery period from general anesthesia. This period of behavioral dysregulation has been called emergence agitation (EA) and emergence delirium (ED). ED and EA occur in the early postoperative period (often within the first 30 minutes). The incidence of ED ranges from 10% to 80% in children and is described as a distressing clinical condition by 42% of pediatric anesthesiologists. Self-harm by the child increases the risk of delayed discharge and may increase the cost of medical care. Sevoflurane is a widely used agent for the induction and maintenance of anesthesia, but its use is associated with the occurrence of ED in the pediatric population. Clinical findings are characterized by hallucinations, struggling, restlessness, crying, and disorientation. In the literature, the Pediatric Anesthesia Rescue Delirium (PAED) Scale Score is used in the diagnosis of ED and EA. This score consists of 5 criteria (maximum score 20) scored using 0-4 point scales. These criteria; The child needs to make eye contact with the caregiver, the child's movements are purposeful, the child is aware of the environment, the child is restless/angry, the child cannot be consoled. While the sensitivity of ≥10 points for the diagnosis of ED is 64% and the specificity is 86%, the sensitivity of >12 points for the diagnosis of ED is 100% and the specificity is 94.5%. Monitoring intraoperative depth of anesthesia in the adult population has been recommended by the American Society of Anesthesiologists (ASA) due to its potential benefits such as faster recovery time and lower drug dosage, as well as prevention of adverse effects such as the incidence of hypotension. The use of anesthesia depth monitors used so far for children is controversial because brain development in children has not yet been completed and the calculation algorithms of these indices are based on adult EEG characteristics. There are very few studies in the literature on the relationship between anesthesia depth monitoring and EA/ED in children, and further studies are needed.

NCT ID: NCT06320743 Recruiting - Anesthesia Clinical Trials

Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

To investigate the effects of non-invasive cerebral and peripheral NIRS monitoring and low and high flow sevoflurane anaesthesia on cerebral and peripheral NIRS in paediatric patients. To determine the effects of two different flows on these monitoring techniques and thus to facilitate intraoperative patient monitoring and to predict complications (hypoxia) that may occur.

NCT ID: NCT06320691 Completed - Anesthesia Clinical Trials

General vs Spinal Anesthesia for Total Joint Arthroplasty-Anterior Approach: A Single-Institution Observational Study

Start date: January 10, 2014
Phase:
Study type: Observational

The study compares the effects of various anesthetic techniques on anterior approach total hip arthroplasty results retrospectively

NCT ID: NCT06317025 Not yet recruiting - Anesthesia Clinical Trials

Design and Development of Multi-modal Intelligent Anesthesia Monitoring System

Start date: May 2024
Phase:
Study type: Observational

This project integrates the characteristics of electroencephalo-graph(EEG), cerebral oxygen, blood pressure, heart rate, etc., based on nonlinear theory and neural oscillation, large sample data and machine learning theory, to develop a multi-modal monitoring system suitable for domestic patients, taking into account changes in sedation, analgesia, cerebral hemodynamics and other factors, regardless of patient age and type of general anesthesia drugs.

NCT ID: NCT06314984 Completed - Anesthesia Clinical Trials

Jet Injectors Versus Conventional Anesthetic Technique in Children

Start date: July 21, 2021
Phase: N/A
Study type: Interventional

This clinical study was conducted to compare the needleless Comfort-in jet injector device and the conventional needle technique in terms of 1. Pain level during the administration of local anesthesia in children. 2. Their effectiveness during pulpotomy procedures in primary molars. Whether comfort-in jet injector device will achieve sufficient anesthesia for the procedures undertaken during pulpotomy or not when compared to the conventional technique and the pain levels of both techniques during the anesthesia step.

NCT ID: NCT06313294 Not yet recruiting - Anesthesia Clinical Trials

Postoperative Follow-up Via Text Messages Automated Versus Telephone in Patients With Continuous Regional Anesthesia

txt-RA
Start date: March 4, 2024
Phase: N/A
Study type: Interventional

Monitoring performed by a trained operator has proven to be useful and valued by patients after the use of continuous regional anesthesia. A health professional calls each patient to gather information about their recovery. However, this direct communication strategy requires time and resources, especially if many patients are involved. A modern and convenient approach involves the use of immediate communication technology for follow-up after a procedure. They may contain specific questions that patients can easily answer from their mobile devices. Automated text messages could be associated with greater convenience and ease for patients with response rates at least like the traditional method. Phone calls, on the other hand, may be less scalable and require more human resources. The objective of the project is to evaluate the feasibility of monitoring through automated electronic messaging by evaluating its usability using a validated scale in Spanish. response rate on the first day and adherence rate compared to that of the traditional method. Secondarily, adherence and differences in satisfaction will be compared.

NCT ID: NCT06312345 Recruiting - Anesthesia Clinical Trials

Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial

Start date: March 11, 2024
Phase: N/A
Study type: Interventional

Ciprofol, a novel intravenous general anesthetic with a chemical structure akin to propofol, boasts significantly enhanced potency. It offers a rapid onset, reduced incidence of injection pain, and minor impact on the cardiovascular system. However, clinical research regarding ciprofol's use for anesthesia induction in cardiac surgery remains limited.

NCT ID: NCT06310265 Recruiting - Anesthesia Clinical Trials

Our Anesthesia Experiment Applied to Child Earthquake Victims in the February 6, 2023 Earthquake

Start date: March 12, 2024
Phase:
Study type: Observational

The study aimed to investigate anesthesia management of pediatric patients in the Ankara Bilkent City Hospital during the earthquake disaster of February 6.