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Gait Disorders, Neurologic clinical trials

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NCT ID: NCT04831879 Recruiting - Parkinson Disease Clinical Trials

Automated Mechanical Peripheral Stimulation to Treat Freezing of Gait in Patients With Parkinson's Disease and STN-DBS

AMBITION
Start date: March 25, 2021
Phase: N/A
Study type: Interventional

The objective is to investigate whether AMPS (Automated Mechanical Peripheral Stimulation) is effective in reduction of FOG measured via the FOG-AC (Freezing Of Gait Assessment Course) in people with Parkinson Disease and STN-DBS (Subthalamic Nucleus Deep Brain Stimulation) in a randomized, double-blind, sham-controlled, cross-over trial

NCT ID: NCT04783493 Recruiting - Clinical trials for Gait Disorders, Neurologic

Transcutaneous Magnetic Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease

TMS
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Dopaminergic drugs partially alleviate gait problems in Parkinson's disease, but the effects are not sustained in the long-term. Particularly, the freezing of gait, balance problems and other gait issues directly impacts patients' quality of life. Experimental epidural spinal cord stimulation studies have suggested positive effects on locomotion among PD patients, but the effects of non invasive stimulation have never been explored.

NCT ID: NCT04770363 Completed - Stroke, Acute Clinical Trials

Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.

NCT ID: NCT04758364 Completed - Clinical trials for Diabetes Mellitus, Type 2

Factors That Effect the Gait Speed in Diabetic Individuals Without Neuropathy

Start date: February 20, 2021
Phase:
Study type: Observational [Patient Registry]

This study planned to investigate the role of potential explanatory factors effecting the speed of gait such as muscle mass, aerobic capacity, physical activity status, cognitive function, blood pressure, and metabolic measures considering age, sex, and education years in diabetic individuals without neuropathy.

NCT ID: NCT04721860 Recruiting - Stroke Clinical Trials

Optimizing Training in Severe Post-Stroke Walking Impairment

BLT2b
Start date: October 15, 2020
Phase: N/A
Study type: Interventional

Difficulty walking is common after a stroke. Although physical rehabilitation helps a little with the improvement of walking ability, recovery is usually incomplete. The purpose of this study is to explore how two different treadmill training approaches influence walking speed, symmetry, and balance in people with chronic severe stroke-related walking impairment. The two approaches involve either forward or backwards treadmill training. This study will look at changes in walking performance and balance, before and after training. This study may lead to more efficient methods for improving walking performance and balance after stroke.

NCT ID: NCT04717323 Completed - Cerebral Palsy Clinical Trials

Precision Gait Retraining for Children With Cerebral Palsy

Start date: November 11, 2020
Phase: N/A
Study type: Interventional

This project will develop the first sensor-based mobile Pelvic Assist Device (mPAD) that can deliver precise, adaptable, pelvic control to restore natural coordination of upper- and lower-limb movements during gait in children with Cerebral Palsy

NCT ID: NCT04707755 Completed - Quality of Life Clinical Trials

Motor Imagery Technique on Lower Limb Function Among Stroke Patients.

Start date: August 30, 2020
Phase: N/A
Study type: Interventional

To determine the effects of motor imagery technique on lower limb function among stroke patient. To determine the effects of motor imagery technique on lower limb spasticity among stroke patients. To determine the effects of motor imagery technique on gait among stroke patients. To determine the effects of motor imagery technique on quality of life among stroke patients

NCT ID: NCT04706572 Recruiting - Parkinson Disease Clinical Trials

Golden Walk as Measure of Gait Rehabilitation in Parkinson's Disease

Start date: June 15, 2020
Phase: N/A
Study type: Interventional

Gait is specifically impaired in Parkinson's disease (PD). External auditory cue based on a binary rhythm tested in PD patients disappear when the stimulus is removed. Golden Ratio (GR)is intrinsic in the human gait, but in PD patients this GR has been found impaired. Aim of the study is the administration of an auditory external cue based on a personalized Golden Ratio-rhythm which could potentially assist people with PD to cope with the difficulties that they experience while walking, thus increasing their mobility and autonomy.

NCT ID: NCT04702815 Completed - Stroke Clinical Trials

Visual Dependence and Multisensory Balance Rehabilitation After Stroke

Start date: February 1, 2020
Phase:
Study type: Observational

This cross-sectional study aims to investigate the prevalence of post-stroke visual dependence, and the effects of visual dependence on balance and gait. It also determines whether visual dependence could differentiate stroke patients with a history of falls from without.

NCT ID: NCT04695496 Recruiting - Clinical trials for Gait Disorders, Neurologic

Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in People With Parkinson's Disease

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Parkinson's disease (PD) is the second most common neurodegenerative disease. The cardinal symptoms of PD are tremor, rigidity, bradykinesia and postural instability. Gait disturbance is also one of the key features of PD. At present, the mainstream treatment of PD is the dopaminergic supplement. However, the response to the medical treatment varies between symptoms. Rigidity and bradykinesia respond to the medical treatment the best, and tremor respond partially. Gait disorders do not usually respond to the dopaminergic medication. Freezing of gait (FOG) is one of the most notorious and devastating presentation of gait disorders in PD. Currently, there is no available treatment for FOG, even the invasive deep brain stimulation does not work on it. Repetitive transcortical magnetic stimulation (rTMS) is a novel non-invasive intervention. Through the magnetic stimulation, brain neurons could be activated by the electrical current. The application of rTMS had been approved by US FDA for the treatment of depression. The possible effect of rTMS may result from the stimulation-related neuronal plasticity. Regarding PD, rTMS also had been found to had some effect on different motor symptoms, mainly on the bradykinesia and rigidity but not gait. The present study would like to test the accumulative effect of rTMS on gait disorders of PD, especially the phenomenon of FOG. All the study subjects will receive rTMS under intermittent theta burst stimulation (iTBS) mode at supplementary motor area (SMA). Gait analysis and other motor performance will be assessed before and after the intervention.