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Pain clinical trials

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NCT ID: NCT04067024 Completed - Pain Clinical Trials

Evaluation of the Effectiveness of the Supraclavicular Block Associated With a Pecs Blocks I to Ensure Analgesia When Placing a Pacemaker

Start date: January 18, 2017
Phase: N/A
Study type: Interventional

Pacemakers are currently placed at the Erasmus Hospital under local anesthesia performed by the surgeon, and the amount of local anesthetic agents sometimes reach the maximum permitted doses, with a risk of systemic toxicity. Moreover, these patients often present an associated conduction block. This represents a contraindication/constraint in the use of lidocaine 2% (local anesthesia frequently used by the surgeon to infiltrate). This study hypothesized that using a block of the supraclavicular nerve associated with a Pecs Block I. guided by ultrasound should require a smaller quantity of local anesthetic.

NCT ID: NCT04064047 Completed - Prostate Cancer Clinical Trials

Anorectal Application of 5% Lidocaine Cream Reduces Pain Prior to Periprostatic Nerve Block During Transrectal Ultrasound Guided Biopsy

Start date: December 2016
Phase: N/A
Study type: Interventional

Transrectal ultrasound guided prostate biopsy is performed with a periprostatic nerve block to the neurovascular bundle bilaterally. This does not reduce the pain due to probe insertion and manipulation prior to nerve blockage. Our study goal is to assess whether topical analgesia would reduce pain during the early stages of the procedure.

NCT ID: NCT04062864 Completed - Pain Clinical Trials

Pupillometer as a Pain Index During General Anesthesia

Start date: August 21, 2019
Phase:
Study type: Observational

This study evaluates the validity of pupil diameter as an indicator of pain during surgery under general anesthesia.

NCT ID: NCT04061265 Completed - Pain Clinical Trials

Articaine Efficacy and Safety for Children Below Age of 4-years

Start date: August 25, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

Pain control is one of the significant behavior determinants in the dental office and shaping the future attitude toward dentistry, especially in children. One of widely used local anesthetic agents is articaine hydrochloride because of its superior potency, over traditionally used 2% lidocaine. Therefore, this study intends to get the benefits of articaine efficiency and apply it in children.

NCT ID: NCT04055090 Completed - Clinical trials for Painful Diabetic Neuropathy

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Start date: February 4, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to explore the overall safety profile and durability of efficacy of Engensis (VM202) in painful diabetic peripheral neuropathy. All subjects still in follow-up for the VMDN-003 study or who have completed the Day 270 visit within the prior 90 days will be approached to enroll in the long-term safety extension study.

NCT ID: NCT04052620 Completed - Pain Clinical Trials

Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study

Start date: October 24, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of diclofenac diethylamine 2.32 percent (%) gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily for 7 days in participants with acute ankle sprain.

NCT ID: NCT04050059 Completed - Pain Clinical Trials

Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS.

Start date: November 13, 2019
Phase: N/A
Study type: Interventional

Nowadays lower segment cesarean sections are preferably carried out under regional anesthesia due to multiple advantages. Local infiltration of lidocaine or any other anesthetic is used before lumber puncture in many centers to reduce needle stick pain. EMLA (eutectic mixture of local anesthetic) cream is the combination of lidocaine and prilocaine which have been effectively used in few studies to reduce needle prick pain. We would like to see which analgesic pretreatment is superior in terms of reducing pain of spinal needle insertion and have better maternal satisfaction levels.

NCT ID: NCT04048265 Completed - Pain Clinical Trials

TMS Treatment in Parkinson's Disease With Pain.

TMSPDP
Start date: May 6, 2019
Phase: N/A
Study type: Interventional

Transcranial magnetic stimulation (TMS) is a procedure that has been shown to improve pain in chronic sufferers. It is a well-tolerated procedure that can be performed on an outpatient basis. It uses a plastic covered coil that sends a magnetic pulse through the skull into the brain and by targeting particular areas in the brain it can be used to help modulate the perception of pain. The study intends to use this technique to treat such a disabling symptom in patients who suffer from Parkinson's Disease (PD). Initially the aim is to study this technique in 48 patients who are suffering from pain and have PD. These patients would require an EEG before and after the stimulation. The stimulation would be performed over ten sessions and the patients would be assessed by a clinician using well recognized clinical tools. It is anticipated that there will be a meaningful improvement in pain. It is also anticipated that TMS is a safe technique to use in patients with PD. The study will be used to help plan a future study that compares TMS with sham technique to prove whether TMS could be an option in the treatment of such a disabling condition.

NCT ID: NCT04040036 Completed - Pain Clinical Trials

Effects of Virtual Reality on Pain, Fear and Anxiety During Blood Draw in Children Aged 5-12 Years Old

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Virtual Reality (VR) has firmly stood amongst other technological devices and can easily be adapted to clinical procedures due to its low cost. It can be easily used particularly in pediatric care units because it appeals to various age groups and can be adapted to mobile phones. Virtual Reality (VR) can be used during painful procedures in children. The aim of this study was to evaluate the effects of two different VR methods on procedure-related pain, fear and anxiety of children aged 5-12 years old during blood draw. This randomized controlled study used parallel trial design.

NCT ID: NCT04039581 Completed - Pain Clinical Trials

KT® in Patients With Cervical Spine Surgery

Start date: October 19, 2019
Phase: N/A
Study type: Interventional

Aim of the study was to investigate the effect of Kinesio taping application on upper trapezius muscle after cervical spine surgery.